{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:36:35Z","timestamp":1791927395457,"version":"4.3.4"},"reference-count":22,"publisher":"American Chemical Society (ACS)","issue":"37","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["18JCQNJC06700"],"award-info":[{"award-number":["18JCQNJC06700"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22401214"],"award-info":[{"award-number":["22401214"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>An efficient synthesis of the 2,3-dihydropyrrolo[3,4-b]indol-1(4H)-ones has been developed via BF3OEt2-promoted formal [3 + 2] annulation of 2-vinylindoles with isocyanates. The reaction features mild conditions and a broad substrate scope, showing excellent functional group tolerance toward various substituents on both the 2-vinylindole and the isocyanate partners. This protocol provides a facile and practical approach, holding significant potential for the synthesis of bioactive heterocyclic compounds and related pharmaceutical intermediates.<\/jats:p>","DOI":"10.1021\/acs.joc.6c01557","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:01:46Z","timestamp":1788476506000},"page":"12751-12756","source":"Crossref","is-referenced-by-count":1,"title":["Construction of\n2,3-Dihydropyrrolo[3,4-\n                    <i>b<\/i>\n                    ]Indol-1(4H)-Ones\nby Formal [3+2] Annulation of 2-Vinylindoles\nwith Isocyanates"],"prefix":"10.1021","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6240-0363","authenticated-orcid":true,"given":"Siyang","family":"Xing","sequence":"first","affiliation":[{"name":"Tianjin Normal University , , ,","place":["Tianjin, People\u2019s Republic of China, 300387"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengjian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tianjin Normal University , , ,","place":["Tianjin, People\u2019s Republic of China, 300387"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tianjin Normal University , , ,","place":["Tianjin, People\u2019s Republic of China, 300387"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiling","family":"Liu","sequence":"additional","affiliation":[{"name":"Tianjin Normal University , , ,","place":["Tianjin, People\u2019s Republic of China, 300387"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Wu","sequence":"additional","affiliation":[{"name":"Tianjin Normal University , , ,","place":["Tianjin, People\u2019s Republic of China, 300387"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yani","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin Normal University , , ,","place":["Tianjin, People\u2019s Republic of China, 300387"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6846-566X","authenticated-orcid":true,"given":"Bolin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Tianjin Normal University , , ,","place":["Tianjin, People\u2019s Republic of China, 300387"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"2026091808090091100_cit1a","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.3987\/COM-06-10772","article-title":"Two new indoloquinazoline alkaloids\nfrom the unripe fruits of Evodia rutaecarpa","volume":"68","author":"Teng","year":"2006","journal-title":"Heterocycles"},{"key":"2026091808090091100_cit1b","doi-asserted-by":"publisher","first-page":"4715","DOI":"10.1016\/j.bmcl.2010.04.024","article-title":"In vivo and in vitro SAR of tetracyclic\nMAPKAP-K2 (MK2) inhibitors. 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