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The synthesis of diverse (hetero)adamantane-based molecules with interchangeable functional groups for broad applications is an area ripe for innovation. The discovery of an expedient and convergent method for the synthesis of (heteroadamantane) scaffolds is described. The convenient synthetic route proceeding via a triple alkylation reaction represents a breakthrough in accessing the adamantane molecular class. Application of this transformation to the synthesis of (hetero)adamantane-based tripods containing tetrel bridgeheads (C- and Ge-) was explored.<\/jats:p>","DOI":"10.1021\/acs.joc.6c01679","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:04:11Z","timestamp":1790611451000},"page":"13466-13474","source":"Crossref","is-referenced-by-count":0,"title":["(Hetero)Adamantane\nSynthesis: A Triple Alkylation\nReaction"],"prefix":"10.1021","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8034-7180","authenticated-orcid":true,"given":"Terry","family":"McCallum","sequence":"first","affiliation":[{"name":"CBN Nano Technologies, Inc. (CBNNT) , , , ,","place":["Ottawa, Ontario, Canada, K1Y 4W5"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Rohe","sequence":"additional","affiliation":[{"name":"CBN Nano Technologies, Inc. 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