{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T08:35:26Z","timestamp":1792571726984,"version":"4.5.0"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Org. Chem."],"published-print":{"date-parts":[[2018,7,6]]},"DOI":"10.1021\/acs.joc.8b00045","type":"journal-article","created":{"date-parts":[[2018,3,21]],"date-time":"2018-03-21T05:05:31Z","timestamp":1521608731000},"page":"7135-7149","source":"Crossref","is-referenced-by-count":40,"title":["Synthesis and Evaluation of Antibacterial Activity of Bottromycins"],"prefix":"10.1021","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1000-3518","authenticated-orcid":true,"given":"Takeshi","family":"Yamada","sequence":"first","affiliation":[{"name":"Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"},{"name":"Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miu","family":"Yagita","sequence":"additional","affiliation":[{"name":"Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goh","family":"Sennari","sequence":"additional","affiliation":[{"name":"Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Shimamura","sequence":"additional","affiliation":[{"name":"Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidehito","family":"Matsui","sequence":"additional","affiliation":[{"name":"Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Horimatsu","sequence":"additional","affiliation":[{"name":"Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Hanaki","sequence":"additional","affiliation":[{"name":"Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyasu","family":"Hirose","sequence":"additional","affiliation":[{"name":"Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"},{"name":"Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"O\u0305mura","sequence":"additional","affiliation":[{"name":"Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3452-6070","authenticated-orcid":true,"given":"Toshiaki","family":"Sunazuka","sequence":"additional","affiliation":[{"name":"Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"},{"name":"Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2018,3,21]]},"reference":[{"key":"ref1\/cit1a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201602164"},{"key":"ref1\/cit1b","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2011.03.117"},{"key":"ref1\/cit1c","doi-asserted-by":"publisher","DOI":"10.1021\/ar6000044"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200804138"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/ja01573a072"},{"key":"ref4\/cit4a","first-page":"47","volume":"18","author":"Nakamura S.","year":"1965","journal-title":"J. Antibiot."},{"key":"ref4\/cit4b","first-page":"1","volume":"20","author":"Nakamura S.","year":"1967","journal-title":"J. Antibiot."},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.36.1076"},{"key":"ref5\/cit5b","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.45.792"},{"key":"ref5\/cit5c","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.55.924"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/ol3022758"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.60.169"},{"key":"ref9\/cit9a","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b09898"},{"key":"ref9\/cit9b","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b09899"},{"key":"ref9\/cit9c","doi-asserted-by":"publisher","DOI":"10.1021\/cb5003587"},{"key":"ref10\/cit10a","first-page":"407","volume":"7","author":"Miller B. M.","year":"1967","journal-title":"Antimicrob. Agents and Chemother."},{"key":"ref10\/cit10b","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.21.75"},{"key":"ref11\/cit11","first-page":"137","volume":"40","author":"Sowa S.","year":"1991","journal-title":"Hiroshima J. Med. Sci."},{"key":"ref12\/cit12a","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1016\/S0021-9258(17)33586-X","volume":"251","author":"Otaka T.","year":"1976","journal-title":"J. Biol. Chem."},{"key":"ref12\/cit12b","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(83)80118-5"},{"key":"ref12\/cit12c","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.23.311"},{"key":"ref13\/cit13a","first-page":"149","volume":"19","author":"Tanaka N.","year":"1966","journal-title":"J. Antibiot."},{"key":"ref13\/cit13b","first-page":"162","volume":"20","author":"Nakamura S.","year":"1967","journal-title":"J. Antibiot."},{"key":"ref13\/cit13c","doi-asserted-by":"publisher","DOI":"10.1021\/jm00310a603"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.08.037"},{"key":"ref15\/cit15a","doi-asserted-by":"publisher","DOI":"10.1246\/bcsj.49.1081"},{"key":"ref15\/cit15b","doi-asserted-by":"publisher","DOI":"10.1246\/bcsj.50.1827"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.8.189"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1039\/b800464a"},{"key":"ref19\/cit19","unstructured":"Kobayashi, Y. Ph.D. dissertation, Kitasato University, Minato-ku, Tokyo, Japan, 2013."},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(02)01405-9"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1139\/v85-511"},{"key":"ref22\/cit22a","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(01)93366-0"},{"key":"ref22\/cit22b","doi-asserted-by":"publisher","DOI":"10.1016\/S0957-4166(00)80091-9"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/jo025957u"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/jo00283a044"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(00)01137-6"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.15227\/orgsyn.081.0262"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200900615"},{"key":"ref33\/cit33","volume-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals. Approved standard M31-A","author":"National Committee for Clinical Laboratory Standards","year":"1999"}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.8b00045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T05:21:20Z","timestamp":1681622480000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.8b00045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,21]]},"references-count":40,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2018,7,6]]}},"alternative-id":["10.1021\/acs.joc.8b00045"],"URL":"https:\/\/doi.org\/10.1021\/acs.joc.8b00045","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,21]]}}}