{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T15:00:02Z","timestamp":1789225202781,"version":"build-2803163510"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T00:00:00Z","timestamp":1579046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T00:00:00Z","timestamp":1579046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T00:00:00Z","timestamp":1579046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100003512","name":"State Administration of Foreign Experts Affairs","doi-asserted-by":"publisher","award":["B07023"],"award-info":[{"award-number":["B07023"]}],"id":[{"id":"10.13039\/501100003512","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["B07023"],"award-info":[{"award-number":["B07023"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003395","name":"Shanghai Municipal Education Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003395","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21572054"],"award-info":[{"award-number":["21572054"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21572055"],"award-info":[{"award-number":["21572055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21738002"],"award-info":[{"award-number":["21738002"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Org. Chem."],"published-print":{"date-parts":[[2020,2,21]]},"DOI":"10.1021\/acs.joc.9b02919","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T11:46:59Z","timestamp":1579088819000},"page":"2725-2732","source":"Crossref","is-referenced-by-count":10,"title":["Copper Promoted Aerobic Oxidative C(sp<sup>3<\/sup>)\u2013C(sp<sup>3<\/sup>) Bond Cleavage of <i>N<\/i>-(2-(Pyridin-2-yl)-ethyl)anilines"],"prefix":"10.1021","volume":"85","author":[{"given":"Yang","family":"Yu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyu","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Shi","sequence":"additional","affiliation":[{"name":"Corporate R&D Division, Firmenich Aromatics (China) Co., Ltd., Shanghai 201108, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6043-0860","authenticated-orcid":true,"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China"},{"name":"Department of Pharmacology and Toxicology and BIO5 Institute, University of Arizona, 1703 E. Mabel Street, P.O. Box 210207, Tucson, Arizona 85721-0207, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8978-0247","authenticated-orcid":true,"given":"Hao","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2020,1,15]]},"reference":[{"key":"ref1\/cit1a","doi-asserted-by":"publisher","DOI":"10.1021\/cr010012i"},{"key":"ref1\/cit1b","doi-asserted-by":"publisher","DOI":"10.1021\/cr050988l"},{"key":"ref1\/cit1c","doi-asserted-by":"publisher","DOI":"10.1039\/b901245c"},{"key":"ref2\/cit2a","doi-asserted-by":"publisher","DOI":"10.1021\/cr400628s"},{"key":"ref2\/cit2b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.7b00108"},{"key":"ref2\/cit2c","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00386F"},{"key":"ref3\/cit3a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200604472"},{"key":"ref3\/cit3b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201100631"},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1021\/ol302939z"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1021\/ol301220s"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/ja9076815"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1501591"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201006779"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1039\/C4RA04419C"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b00652"},{"key":"ref10\/cit10a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201202880"},{"key":"ref10\/cit10b","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2013.07.056"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1126\/science.aat6365"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201903019"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1259520"},{"key":"ref14\/cit14a","doi-asserted-by":"publisher","DOI":"10.1039\/c1cs15082k"},{"key":"ref14\/cit14b","doi-asserted-by":"publisher","DOI":"10.1021\/cr300527g"},{"key":"ref14\/cit14c","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201605104"},{"key":"ref14\/cit14d","doi-asserted-by":"publisher","DOI":"10.1021\/ol1030298"},{"key":"ref14\/cit14e","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b01114"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201100225"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b01230"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b03799"},{"key":"ref18\/cit18a","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b01435"},{"key":"ref18\/cit18b","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.6b02206"},{"key":"ref18\/cit18c","doi-asserted-by":"publisher","DOI":"10.1039\/C8QO00826D"},{"key":"ref18\/cit18d","doi-asserted-by":"publisher","DOI":"10.1039\/c2ob25682g"},{"key":"ref18\/cit18e","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2014.12.146"},{"key":"ref19\/cit19a","doi-asserted-by":"publisher","DOI":"10.1021\/jm00288a024"},{"key":"ref19\/cit19b","doi-asserted-by":"publisher","DOI":"10.1021\/jm00135a003"},{"key":"ref19\/cit19c","doi-asserted-by":"publisher","DOI":"10.1021\/ja0260465"},{"key":"ref19\/cit19d","doi-asserted-by":"publisher","DOI":"10.1021\/jo047924f"},{"key":"ref19\/cit19e","doi-asserted-by":"publisher","DOI":"10.1039\/C4OB00066H"},{"key":"ref19\/cit19f","unstructured":"fCotari, J.; Wang, Z. Compositions and Methods of Making Expanded Hematopoietic Stem Cells Using Derivatives of Fluorene. WO Patent 084452A1, 2019."},{"key":"ref20\/cit20a","doi-asserted-by":"publisher","DOI":"10.1002\/prac.19893310418"},{"key":"ref20\/cit20b","doi-asserted-by":"publisher","DOI":"10.1021\/ol300781s"},{"key":"ref20\/cit20c","doi-asserted-by":"publisher","DOI":"10.1021\/ol303437m"},{"key":"ref21\/cit21a","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.8b01555"},{"key":"ref21\/cit21b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b03542"},{"key":"ref21\/cit21c","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1260211"},{"key":"ref21\/cit21d","doi-asserted-by":"publisher","DOI":"10.1021\/jo060847z"},{"key":"ref21\/cit21e","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201600226"},{"key":"ref21\/cit21f","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201800783"},{"key":"ref21\/cit21g","doi-asserted-by":"publisher","DOI":"10.1021\/ja01617a054"},{"key":"ref21\/cit21h","doi-asserted-by":"publisher","DOI":"10.1039\/C8CC05285A"},{"key":"ref22\/cit22","unstructured":"Hood, J.; KC, S. K. Indazole-3-caboxamides and Their Use as Wnt\/B-catenin Signaling Pathway Inhibitors. WO Patent 040215A1, 2013."},{"key":"ref23\/cit23","unstructured":"Muller, G. W.; Chen, R. S. C.; Rucheiman, A. L. 5-Subtituted Isoindoline Compounds. WO Patent 027542A2, 2018."}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.9b02919","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T01:21:50Z","timestamp":1682126510000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.9b02919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,15]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,2,21]]}},"alternative-id":["10.1021\/acs.joc.9b02919"],"URL":"https:\/\/doi.org\/10.1021\/acs.joc.9b02919","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,15]]}}}