{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:16:54Z","timestamp":1790831814781,"version":"4.1.0"},"reference-count":55,"publisher":"American Chemical Society (ACS)","issue":"26","license":[{"start":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T00:00:00Z","timestamp":1687392000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI163142"],"award-info":[{"award-number":["R01AI163142"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Phys. Chem. B"],"published-print":{"date-parts":[[2023,7,6]]},"DOI":"10.1021\/acs.jpcb.3c02356","type":"journal-article","created":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T05:52:52Z","timestamp":1687499572000},"page":"5837-5849","source":"Crossref","is-referenced-by-count":32,"title":["Excluded Volume and Weak Interactions in Crowded Solutions Modulate Conformations and RNA Binding of an Intrinsically Disordered Tail"],"prefix":"10.1021","volume":"127","author":[{"given":"Madison A.","family":"Stringer","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States"},{"name":"Center for Biomolecular Condensates, Washington University in St Louis, 1 Brookings Drive, Saint Louis, Missouri 63130, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine","family":"Cubuk","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States"},{"name":"Center for Biomolecular Condensates, Washington University in St Louis, 1 Brookings Drive, Saint Louis, Missouri 63130, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Jerem\u00edas","family":"Incicco","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debjit","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States"},{"name":"Center for Biomolecular Condensates, Washington University in St Louis, 1 Brookings Drive, Saint Louis, Missouri 63130, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2276-0310","authenticated-orcid":true,"given":"Kathleen B.","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa D.","family":"Stuchell-Brereton","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States"},{"name":"Center for Biomolecular Condensates, Washington University in St Louis, 1 Brookings Drive, Saint Louis, Missouri 63130, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8394-7993","authenticated-orcid":true,"given":"Andrea","family":"Soranno","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States"},{"name":"Center for Biomolecular Condensates, Washington University in St Louis, 1 Brookings Drive, Saint Louis, Missouri 63130, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,6,22]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2017.17"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(91)90499-v"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1002\/jmr.695"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3257"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00753"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b13025"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1417415112"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/bies.201300080"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biophys.37.032807.125817"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/s0968-0004(01)01938-7"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/s0959-440x(99)00045-7"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/ja305300m"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2010.01.008"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1322611111"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/syst.202100051"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21165908"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1103\/physrevlett.114.068303"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202016804"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3475"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/jz401817x"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2016.05.033"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1921617117"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/ja5073146"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2017.10.030"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1051\/jphys:0198500460110185300"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1063\/1.465909"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-60093-7","volume-title":"Excluded Volume Effects in Polymer Solutions","author":"Sch\u00e4fer L.","year":"1999"},{"key":"ref28\/cit28","series-title":"Lecture Notes in Physics","doi-asserted-by":"crossref","DOI":"10.1007\/978-94-007-1223-2","volume-title":"Colloids and the Depletion Interaction","author":"Lekkerkerker H. N. W.","year":"2011"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.3c01619"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2018.03.007"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-022-00811-w"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21953-3"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1101\/2023.02.10.527914"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1316039111"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1063\/5.0045492"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2215371120"},{"key":"ref37\/cit37","volume-title":"Scaling Concepts in Polymer Physics","author":"de Gennes P.-G.","year":"1979"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-062215-010915"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/ma60071a040"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0601395103"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1039\/b813961j"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1207719109"},{"key":"ref43\/cit43","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198520597.001.0001","volume-title":"Polymer Physics","author":"Rubinstein M.","year":"2003"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/bip.360260408"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/s0301-4622(02)00009-1"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/ja407009w"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1313006111"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0900622106"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.5b00246"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1002\/bip.22662"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/pro.4573"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.202200406"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1021\/bi901273r"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1007\/s10930-009-9201-4"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.7554\/elife.57309"}],"container-title":["The Journal of Physical Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jpcb.3c02356","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jpcb.3c02356","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T14:50:52Z","timestamp":1702651852000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jpcb.3c02356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,22]]},"references-count":55,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2023,7,6]]}},"alternative-id":["10.1021\/acs.jpcb.3c02356"],"URL":"https:\/\/doi.org\/10.1021\/acs.jpcb.3c02356","relation":{},"ISSN":["1520-6106","1520-5207"],"issn-type":[{"value":"1520-6106","type":"print"},{"value":"1520-5207","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,22]]}}}