{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T09:14:43Z","timestamp":1758273283598,"version":"3.37.3"},"reference-count":76,"publisher":"American Chemical Society (ACS)","issue":"19","license":[{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL107046"],"award-info":[{"award-number":["R01HL107046"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Phys. Chem. B"],"published-print":{"date-parts":[[2024,5,16]]},"DOI":"10.1021\/acs.jpcb.4c01601","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T12:03:15Z","timestamp":1714996995000},"page":"4716-4727","source":"Crossref","is-referenced-by-count":2,"title":["Myosin-Catalyzed ATP Hydrolysis in the Presence of Disease-Causing Mutations: Mavacamten as a Way to Repair Mechanism"],"prefix":"10.1021","volume":"128","author":[{"given":"Ananya","family":"Chakraborti","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jil C.","family":"Tardiff","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Arizona, Tucson, Arizona 85724, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0308-1059","authenticated-orcid":true,"given":"Steven D.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2024,5,6]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1\/cit1","DOI":"10.1161\/CIRCRESAHA.113.300282"},{"doi-asserted-by":"publisher","key":"ref2\/cit2","DOI":"10.1038\/s41569-020-0428-2"},{"doi-asserted-by":"publisher","key":"ref3\/cit3","DOI":"10.1016\/j.jacc.2016.08.079"},{"doi-asserted-by":"publisher","key":"ref4\/cit4","DOI":"10.1016\/j.jacc.2015.01.019"},{"doi-asserted-by":"publisher","key":"ref5\/cit5","DOI":"10.1016\/j.ijcha.2020.100503"},{"doi-asserted-by":"publisher","key":"ref6\/cit6","DOI":"10.1161\/CIRCRESAHA.117.311059"},{"doi-asserted-by":"publisher","key":"ref7\/cit7","DOI":"10.1001\/jama.287.10.1308"},{"doi-asserted-by":"publisher","key":"ref8\/cit8","DOI":"10.3390\/jcm10081547"},{"doi-asserted-by":"publisher","key":"ref9\/cit9","DOI":"10.3390\/jcm12186093"},{"doi-asserted-by":"publisher","key":"ref10\/cit10","DOI":"10.1085\/jgp.202012662"},{"doi-asserted-by":"publisher","key":"ref11\/cit11","DOI":"10.1242\/jcs.094300"},{"doi-asserted-by":"publisher","key":"ref12\/cit12","DOI":"10.1088\/0953-8984\/25\/46\/463101"},{"doi-asserted-by":"publisher","key":"ref13\/cit13","DOI":"10.1101\/cshperspect.a021931"},{"doi-asserted-by":"publisher","key":"ref14\/cit14","DOI":"10.1007\/s00018-012-1131-1"},{"doi-asserted-by":"publisher","key":"ref15\/cit15","DOI":"10.1021\/bi00801a004"},{"doi-asserted-by":"publisher","key":"ref16\/cit16","DOI":"10.1146\/annurev.biophys.050708.133751"},{"doi-asserted-by":"publisher","key":"ref17\/cit17","DOI":"10.1002\/cm.21695"},{"doi-asserted-by":"publisher","key":"ref18\/cit18","DOI":"10.1007\/s12265-009-9129-2"},{"doi-asserted-by":"publisher","key":"ref19\/cit19","DOI":"10.1038\/s41467-019-10555-9"},{"doi-asserted-by":"publisher","key":"ref20\/cit20","DOI":"10.1007\/s12551-020-00721-5"},{"doi-asserted-by":"publisher","key":"ref21\/cit21","DOI":"10.1172\/JCI148557"},{"doi-asserted-by":"publisher","key":"ref22\/cit22","DOI":"10.1016\/j.jbc.2021.101297"},{"doi-asserted-by":"publisher","key":"ref23\/cit23","DOI":"10.1016\/S0140-6736(20)31792-X"},{"doi-asserted-by":"publisher","key":"ref24\/cit24","DOI":"10.1007\/s40265-022-01739-7"},{"doi-asserted-by":"publisher","key":"ref25\/cit25","DOI":"10.2147\/DDDT.S368590"},{"doi-asserted-by":"publisher","key":"ref26\/cit26","DOI":"10.2144\/fsoa-2023-0059"},{"doi-asserted-by":"publisher","key":"ref27\/cit27","DOI":"10.1126\/science.aad3456"},{"doi-asserted-by":"publisher","key":"ref28\/cit28","DOI":"10.1074\/jbc.M117.776815"},{"doi-asserted-by":"publisher","key":"ref29\/cit29","DOI":"10.1085\/jgp.202012789"},{"doi-asserted-by":"publisher","key":"ref30\/cit30","DOI":"10.1074\/jbc.RA120.016506"},{"doi-asserted-by":"publisher","key":"ref31\/cit31","DOI":"10.1016\/j.jmb.2021.167295"},{"doi-asserted-by":"publisher","key":"ref32\/cit32","DOI":"10.1111\/bph.15271"},{"doi-asserted-by":"publisher","key":"ref33\/cit33","DOI":"10.1161\/JAHA.118.009627"},{"doi-asserted-by":"publisher","key":"ref34\/cit34","DOI":"10.1126\/sciadv.abo7622"},{"doi-asserted-by":"publisher","key":"ref35\/cit35","DOI":"10.1073\/pnas.2314914121"},{"doi-asserted-by":"publisher","key":"ref36\/cit36","DOI":"10.1073\/pnas.1809540115"},{"doi-asserted-by":"publisher","key":"ref37\/cit37","DOI":"10.1073\/pnas.1720342115"},{"doi-asserted-by":"publisher","key":"ref38\/cit38","DOI":"10.23919\/CinC53138.2021.9662736"},{"doi-asserted-by":"publisher","key":"ref39\/cit39","DOI":"10.1016\/j.yjmcc.2020.06.003"},{"doi-asserted-by":"publisher","key":"ref40\/cit40","DOI":"10.1085\/jgp.202012640"},{"doi-asserted-by":"publisher","key":"ref41\/cit41","DOI":"10.1152\/ajpheart.00023.2020"},{"doi-asserted-by":"publisher","key":"ref42\/cit42","DOI":"10.1016\/S0006-3495(01)75921-8"},{"doi-asserted-by":"publisher","key":"ref43\/cit43","DOI":"10.1073\/pnas.1401862111"},{"doi-asserted-by":"publisher","key":"ref44\/cit44","DOI":"10.1016\/j.sbi.2015.04.006"},{"doi-asserted-by":"publisher","key":"ref45\/cit45","DOI":"10.1016\/j.ymeth.2021.02.017"},{"doi-asserted-by":"publisher","key":"ref46\/cit46","DOI":"10.1016\/j.sjbs.2020.10.023"},{"doi-asserted-by":"publisher","key":"ref47\/cit47","DOI":"10.1101\/2023.11.15.567213"},{"doi-asserted-by":"publisher","key":"ref48\/cit48","DOI":"10.1140\/epjst\/e2015-02419-6"},{"doi-asserted-by":"publisher","key":"ref49\/cit49","DOI":"10.1021\/acs.jpcb.0c05762"},{"doi-asserted-by":"publisher","key":"ref50\/cit50","DOI":"10.1021\/acs.jpcb.1c03144"},{"doi-asserted-by":"publisher","key":"ref51\/cit51","DOI":"10.1021\/acs.jpcb.2c06679"},{"doi-asserted-by":"publisher","key":"ref52\/cit52","DOI":"10.1021\/acs.jpcb.2c03251"},{"doi-asserted-by":"publisher","key":"ref53\/cit53","DOI":"10.1021\/acs.jpcb.2c07243"},{"doi-asserted-by":"publisher","key":"ref54\/cit54","DOI":"10.1073\/pnas.1309493110"},{"doi-asserted-by":"publisher","key":"ref55\/cit55","DOI":"10.1074\/jbc.M113.511204"},{"doi-asserted-by":"publisher","key":"ref56\/cit56","DOI":"10.1074\/jbc.RA119.010563"},{"doi-asserted-by":"publisher","key":"ref57\/cit57","DOI":"10.1073\/pnas.2025030118"},{"doi-asserted-by":"publisher","key":"ref58\/cit58","DOI":"10.1074\/jbc.M115.681874"},{"doi-asserted-by":"publisher","key":"ref59\/cit59","DOI":"10.7554\/eLife.63691"},{"doi-asserted-by":"publisher","key":"ref60\/cit60","DOI":"10.1038\/s41467-017-00176-5"},{"doi-asserted-by":"publisher","key":"ref61\/cit61","DOI":"10.1021\/bi5015166"},{"doi-asserted-by":"publisher","key":"ref62\/cit62","DOI":"10.1007\/s10822-013-9644-8"},{"volume-title":"LigPrep","year":"2023","author":"Schr\u00f6dinger","key":"ref63\/cit63"},{"doi-asserted-by":"publisher","key":"ref64\/cit64","DOI":"10.1021\/jm0306430"},{"doi-asserted-by":"publisher","key":"ref65\/cit65","DOI":"10.1021\/jm030644s"},{"doi-asserted-by":"publisher","key":"ref66\/cit66","DOI":"10.1002\/prot.10613"},{"doi-asserted-by":"publisher","key":"ref67\/cit67","DOI":"10.1016\/S0022-2836(02)00470-9"},{"doi-asserted-by":"publisher","key":"ref68\/cit68","DOI":"10.1016\/0263-7855(96)00018-5"},{"doi-asserted-by":"publisher","key":"ref69\/cit69","DOI":"10.1002\/jcc.20289"},{"doi-asserted-by":"publisher","key":"ref70\/cit70","DOI":"10.1002\/jcc.21287"},{"doi-asserted-by":"publisher","key":"ref71\/cit71","DOI":"10.1021\/ci3003649"},{"doi-asserted-by":"publisher","key":"ref72\/cit72","DOI":"10.1002\/jcc.540100208"},{"doi-asserted-by":"publisher","key":"ref73\/cit73","DOI":"10.1039\/A702304I"},{"doi-asserted-by":"publisher","key":"ref74\/cit74","DOI":"10.1524\/zpch.2008.5395"},{"doi-asserted-by":"publisher","key":"ref75\/cit75","DOI":"10.1021\/jp9809890"},{"doi-asserted-by":"publisher","key":"ref76\/cit76","DOI":"10.1021\/acs.jctc.2c00734"}],"container-title":["The Journal of Physical Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jpcb.4c01601","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jpcb.4c01601","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T08:20:09Z","timestamp":1715847609000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jpcb.4c01601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,6]]},"references-count":76,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2024,5,16]]}},"alternative-id":["10.1021\/acs.jpcb.4c01601"],"URL":"https:\/\/doi.org\/10.1021\/acs.jpcb.4c01601","relation":{},"ISSN":["1520-6106","1520-5207"],"issn-type":[{"type":"print","value":"1520-6106"},{"type":"electronic","value":"1520-5207"}],"subject":[],"published":{"date-parts":[[2024,5,6]]}}}