{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:29:03Z","timestamp":1792621743073,"version":"4.5.0"},"reference-count":71,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T00:00:00Z","timestamp":1700784000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T00:00:00Z","timestamp":1700784000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T00:00:00Z","timestamp":1700784000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS114413"],"award-info":[{"award-number":["R01NS114413"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS124784"],"award-info":[{"award-number":["R01NS124784"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001790","name":"Ara Parseghian Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001790","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P20GM103620"],"award-info":[{"award-number":["P20GM103620"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1655494"],"award-info":[{"award-number":["1655494"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2024,1,5]]},"DOI":"10.1021\/acs.jproteome.3c00375","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T15:27:33Z","timestamp":1700839653000},"page":"84-94","source":"Crossref","is-referenced-by-count":4,"title":["Comparative Hippocampal Proteome and Phosphoproteome in a Niemann\u2013Pick, Type C1 Mouse Model Reveal Insights into Disease Mechanisms"],"prefix":"10.1021","volume":"23","author":[{"given":"Thu T. A.","family":"Nguyen","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1520-7974","authenticated-orcid":true,"given":"Varshasnata","family":"Mohanty","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1459-2038","authenticated-orcid":true,"given":"Ying","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3636-7264","authenticated-orcid":true,"given":"Kevin R.","family":"Francis","sequence":"additional","affiliation":[{"name":"Cellular Therapies and Stem Cell Biology Group, Sanford Research, Sioux Falls, South Dakota 57104, United States"},{"name":"Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, South Dakota 57105, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3541-3361","authenticated-orcid":true,"given":"Stephanie M.","family":"Cologna","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States"},{"name":"Laboratory of Integrated Neuroscience, University of Illinois Chicago, Chicago, Illinois 60607, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,11,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/0925-4439(94)90001-9"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.31.4.317"},{"issue":"1","key":"ref3\/cit3","first-page":"118","volume":"58","author":"Vanier M. T.","year":"1996","journal-title":"Am. J. Hum. Genet."},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5323.228"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1126\/science.290.5500.2298"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0308456101"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.03.049"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.42.12.2286"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/BF00685003"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1039\/d2mo00004k"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047845"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201800432"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-019-0440-9"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200500412"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1039\/d2mo00004k"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00440"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.4103\/0972-2327.104323"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-023-01020-1"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901240303"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2009.215"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2011.04.003"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2013.04.006"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/118.1.119"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-021-05337-5"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12970"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-019-01989-7"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-019-02223-5"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1586\/epr.12.15"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.RA120.002105"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpro.2022.100477"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac194"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.35395"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/dds193"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11425-0"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1007\/s10048-012-0337-6"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2011.07.002"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2011-100542"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/s10038-020-0803-1"},{"issue":"3","key":"ref39\/cit39","first-page":"461","volume":"55","author":"Boespflug-Tanguy O.","year":"1994","journal-title":"Am. J. Hum Genet."},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1159\/000111361"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200110138"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.12.037"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2019.00363"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20462"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.811686"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.40316"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1108774108"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1039\/c000094a"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.6b00098"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3390\/cells11030581"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-013-9610-6"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/glia.21001"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18071442"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22126600"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20985"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddg025"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.10.042"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e11-04-0332r"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0807450105"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1126\/science.1128134"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2007.01.002"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aaf6716"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0420-19.2020"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.614420"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.60360"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2018.00445"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M700170-MCP200"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2012.05.003"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2012.08.016"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.12.055"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2021.11.008"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.3c00375","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.3c00375","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T09:14:24Z","timestamp":1704446064000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.3c00375"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,24]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1,5]]}},"alternative-id":["10.1021\/acs.jproteome.3c00375"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.3c00375","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,24]]}}}