{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:38:22Z","timestamp":1791815902896,"version":"4.3.4"},"reference-count":26,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Immunovia AB"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2025,1,3]]},"DOI":"10.1021\/acs.jproteome.4c00752","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T16:31:52Z","timestamp":1734625912000},"page":"315-322","source":"Crossref","is-referenced-by-count":19,"title":["Biomarker Discovery for Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC) Using Multiplex Proteomics Technology"],"prefix":"10.1021","volume":"24","author":[{"given":"Alcibiade","family":"Athanasiou","sequence":"first","affiliation":[{"name":"Proteomedix AG, Wagistrasse 23, CH-8952 Schlieren, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Kureshi","sequence":"additional","affiliation":[{"name":"Immunovia Inc., 26 Forest Street, Suite 110, Marlborough, Massachusetts 01752, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Wittig","sequence":"additional","affiliation":[{"name":"Proteomedix AG, Wagistrasse 23, CH-8952 Schlieren, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Sterner","sequence":"additional","affiliation":[{"name":"Immunovia AB, Medicon Village, Scheelev\u00e4gen 8, SE-223 63 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramy","family":"Huber","sequence":"additional","affiliation":[{"name":"Proteomedix AG, Wagistrasse 23, CH-8952 Schlieren, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma A.","family":"Palma","sequence":"additional","affiliation":[{"name":"Immunovia Inc., 26 Forest Street, Suite 110, Marlborough, Massachusetts 01752, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"King","sequence":"additional","affiliation":[{"name":"Immunovia Inc., 26 Forest Street, Suite 110, Marlborough, Massachusetts 01752, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4955-1295","authenticated-orcid":true,"given":"Ralph","family":"Schiess","sequence":"additional","affiliation":[{"name":"Proteomedix AG, Wagistrasse 23, CH-8952 Schlieren, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-0155"},{"key":"ref2\/cit2","unstructured":"National Cancer Institute. Surveillance, Epidemiology, and End Results Program. Cancer Stat\nFacts: Pancreatic Cancer. https:\/\/seer.cancer.gov\/statfacts\/html\/pancreas.html#content (accessed August 26, 2024)."},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00141-0"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1404198"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-255X(00)80105-5"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-4864-3"},{"key":"ref7\/cit7","unstructured":"National Comprehensive Cancer Network. NCCN Guidelines Version 1.2023: Genetic\/Familial\nHigh-Risk Assessment: Breast, Ovarian, and Pancreatic. https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/genetics_bop.pdf (accessed August 26, 2024)."},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.12865\/chsj.43.02.05"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2017.04.009"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.14309\/ctg.0000000000000468"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2015.64.0730"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.05.035"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2015.09.017"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i32.11230"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2006.08.2644"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0000000000000368"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23907"},{"issue":"3","key":"ref18\/cit18","first-page":"512","volume":"58","author":"Narimatsu H.","year":"1998","journal-title":"Cancer Res."},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.66.5265"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2012-0744"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.77.6658"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0095192"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0243487"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19980430)17:8<891::AID-SIM780>3.0.CO;2-B"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"issue":"4","key":"ref26\/cit26","first-page":"350","volume":"85","author":"Steinberg W.","year":"1990","journal-title":"Am. J. Gastroenterol."}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.4c00752","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.4c00752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T10:32:05Z","timestamp":1740479525000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.4c00752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,19]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,3]]}},"alternative-id":["10.1021\/acs.jproteome.4c00752"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.4c00752","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,19]]}}}