{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:40:37Z","timestamp":1791402037181,"version":"4.3.3"},"reference-count":61,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82100778"],"award-info":[{"award-number":["82100778"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273657"],"award-info":[{"award-number":["82273657"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangxi Clinical Research Center for Cardio-cerebrovascular Diseases","award":["AD17129014"],"award-info":[{"award-number":["AD17129014"]}]},{"name":"Guangxi Key Laboratory of Precision Medicine in Cardio-cerebrovascular Diseases Control and Prevention","award":["22-035-18"],"award-info":[{"award-number":["22-035-18"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2026,3,6]]},"DOI":"10.1021\/acs.jproteome.5c00555","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T21:04:38Z","timestamp":1770152678000},"page":"1319-1328","source":"Crossref","is-referenced-by-count":2,"title":["Plasma Proteomic Signatures of Accelerometer-Measured Sedentary Behavior Are Associated with Future Disease Risk"],"prefix":"10.1021","volume":"25","author":[{"given":"Sijia","family":"Dai","sequence":"first","affiliation":[{"name":"Department of Toxicology, School of Public Health, Guangxi Medical University, Shuangyong Road 22, Nanning, Guangxi 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Toxicology, School of Public Health, Guangxi Medical University, Shuangyong Road 22, Nanning, Guangxi 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoni","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Toxicology, School of Public Health, Guangxi Medical University, Shuangyong Road 22, Nanning, Guangxi 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangfeng","family":"Long","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Children\u2019s Hospital of Nanjing Medical University, Guangzhou Road 72, Nanjing 210008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haobing","family":"Huang","sequence":"additional","affiliation":[{"name":"Cardiovascular Surgery","place":["Nanjing, China"]},{"name":"the First Affiliated Hospital with Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2605-2100","authenticated-orcid":true,"given":"Cheng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Toxicology, School of Public Health, Guangxi Medical University, Shuangyong Road 22, Nanning, Guangxi 530021, China"},{"name":"Guangxi Key Laboratory of Precision Medicine in Cardio-Cerebrovascular Diseases Control and Prevention, No. 6 Shuangyong Road, Nanning, Guangxi 530021, China"},{"name":"Guangxi Clinical Research Center for Cardio-Cerebrovascular Diseases, No. 6 Shuangyong Road, Nanning, Guangxi 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1186\/s12966-017-0525-8"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-publhealth-040119-094201"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2020-103640"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq451"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2020.2045"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jshs.2025.101088"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012554.pub2"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.4082\/kjfm.20.0165"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/S1672-0229(07)60018-7"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaf1058"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.adf5681"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-024-03142-z"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41562-024-02078-1"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s43016-024-01059-x"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-025-03268-7"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0203-z"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001779"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.05.046"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-7568(23)00056-9"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07743-4"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2021-105132"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.15231"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-43575-7"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06592-6"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.02.031"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15553-w"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.2337\/dc21-1512"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i582"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06563-x"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jshs.2024.100973"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.136642"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvr.2023.200271"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.110207"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1136\/thorax-2024-22239"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-025-03229-2"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13021"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.625950"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1126\/science.abp8964"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094496"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00022.2022"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2015.05.006"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.27173"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00427.2015"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01430-7"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1124\/pharmrev.120.000096"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01379-7"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-022-00590-z"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-024-00889-z"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06802-1"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/hvae149"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.018020"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-56935-2"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-020-0268-2"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-61720-2"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a029694"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-020-09855-3"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.24f15261"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2020-103270"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1007\/s12170-008-0054-8"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-025-02238-x"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.043030"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.5c00555","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.5c00555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T07:32:43Z","timestamp":1773214363000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.5c00555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,3]]},"references-count":61,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3,6]]}},"alternative-id":["10.1021\/acs.jproteome.5c00555"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.5c00555","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,3]]}}}