{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T21:30:59Z","timestamp":1780781459648,"version":"3.54.1"},"reference-count":51,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["21JCZDJC00430"],"award-info":[{"award-number":["21JCZDJC00430"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Xin?Sun Famous Traditional Chinese Medicine Doctor Studio in Tianjin"},{"name":"Tianjin Young Medical Emerging Talent Program","award":["TJSQNYXXRD2070"],"award-info":[{"award-number":["TJSQNYXXRD2070"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2026,1,2]]},"DOI":"10.1021\/acs.jproteome.5c00656","type":"journal-article","created":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:59:42Z","timestamp":1765295982000},"page":"341-356","source":"Crossref","is-referenced-by-count":1,"title":["Serum Omics Analysis Reveals Tissue Damage and Metabolic Reprogramming in Cavitary Pulmonary Tuberculosis"],"prefix":"10.1021","volume":"25","author":[{"given":"Jianhai","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Tuberculosis, Haihe Clinical School","place":["Tianjin, China"]},{"name":"Tianjin Medical University","place":["Tianjin, China"]},{"name":"Tianjin Key Laboratory of Lung Regenerative Medicine","place":["Tianjin, China"]},{"name":"Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Haihe Hospital","place":["Tianjin, China"]},{"name":"Tianjin University","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunnan","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Tuberculosis, Haihe Clinical School","place":["Tianjin, China"]},{"name":"Tianjin Medical University","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibai","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Haihe Hospital","place":["Tianjin, China"]},{"name":"Tianjin University","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunfeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Tuberculosis, Haihe Clinical School","place":["Tianjin, China"]},{"name":"Tianjin Medical University","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuming","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Haihe Hospital","place":["Tianjin, China"]},{"name":"Tianjin University","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhoumao","family":"Cairang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory","place":["Tongren, China"]},{"name":"Huangnan Tibetan Autonomous Prefecture People\u2019s Hospital","place":["Tongren, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory","place":["Tongren, China"]},{"name":"Huangnan Tibetan Autonomous Prefecture People\u2019s Hospital","place":["Tongren, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gazang","family":"Zhuoma","sequence":"additional","affiliation":[{"name":"Department of Infection","place":["Tongren, China"]},{"name":"Huangnan Tibetan Autonomous Prefecture People\u2019s Hospital","place":["Tongren, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Infection","place":["Tongren, China"]},{"name":"Huangnan Tibetan Autonomous Prefecture People\u2019s Hospital","place":["Tongren, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingcuo","family":"Ren","sequence":"additional","affiliation":[{"name":"High Altitude Characteristic Medical Research Institute, Huangnan Tibetan Autonomous Prefecture People\u2019s Hospital","place":["Tongren, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Sun","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital","place":["Tianjin, China"]},{"name":"Nankai University","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1201-0535","authenticated-orcid":true,"given":"Huaiyong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Tuberculosis, Haihe Clinical School","place":["Tianjin, China"]},{"name":"Tianjin Medical University","place":["Tianjin, China"]},{"name":"Department of Respiratory Medicine, Haihe Hospital","place":["Tianjin, China"]},{"name":"Tianjin University","place":["Tianjin, China"]},{"name":"Tianjin Key Laboratory of Lung Regenerative Medicine","place":["Tianjin, China"]},{"name":"Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,12,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/s2213-2600(24)00028-6"},{"key":"ref2\/cit2","unstructured":"WHO Global Tuberculosis Report\n                      2024. https:\/\/www.who.int\/teams\/global-tuberculosis-programme\/tb-reports\/global-tuberculosis-report-2024."},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2024.107325"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00962"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00036-20"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2023.06.043"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2022.101672"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11111081"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-022-08997-9"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.02284"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30148-1"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2022.05.013"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1965.92.5.687"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c02563"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-021-01401-5"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00060-07"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2004.04.007"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.ado5951"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1012565"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201807-1361OC"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1186\/s12865-023-00563-2"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jctube.2022.100308"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127087"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2024.119717"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.019435"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13030432"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3390\/tomography8040137"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268817000279"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241914806"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.3390\/metabo12100933"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v12.i23.5283"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.026"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.18632\/aging.203936"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-53738-9"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-020-0551-8"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciae538"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-023-03636-x"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-022-01172-0"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1080\/1040841x.2024.2370979"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093397"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.7861\/clinmedicine.12-1-40"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3200"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01780-07"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-247396"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.625617"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12113.x"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2022.119502"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2020.121891"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2017.04.007"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2024.102545"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA09250A"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.5c00656","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.5c00656","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T13:03:43Z","timestamp":1768568623000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.5c00656"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,9]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,2]]}},"alternative-id":["10.1021\/acs.jproteome.5c00656"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.5c00656","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,9]]}}}