{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T12:23:14Z","timestamp":1772454194005,"version":"3.50.1"},"reference-count":33,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100004479","name":"Natural Science Foundation of Jiangxi Province","doi-asserted-by":"publisher","award":["20232BAB206100"],"award-info":[{"award-number":["20232BAB206100"]}],"id":[{"id":"10.13039\/501100004479","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2026,1,2]]},"DOI":"10.1021\/acs.jproteome.5c00657","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T15:45:12Z","timestamp":1765899912000},"page":"329-340","source":"Crossref","is-referenced-by-count":1,"title":["Multilayered Regulatory Dynamics of p53 Mutations and Platinum Resistance in Ovarian Cancer"],"prefix":"10.1021","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0217-4290","authenticated-orcid":true,"given":"Liling","family":"Hu","sequence":"first","affiliation":[{"name":"MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology","place":["Guangzhou, China"]},{"name":"Jinan University","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanchen","family":"Zou","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology","place":["Guangzhou, China"]},{"name":"Jinan University","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LvYing","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, The First Affiliated Hospital, Jiangxi Medical College","place":["Nanchang, China"]},{"name":"Nanchang University","place":["Nanchang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, The First Affiliated Hospital, Jiangxi Medical College","place":["Nanchang, China"]},{"name":"Nanchang University","place":["Nanchang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danya","family":"Liu","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology","place":["Guangzhou, China"]},{"name":"Jinan University","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangli","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology","place":["Wuzhou, China"]},{"name":"Wuzhou Red Cross Hospital","place":["Wuzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuying","family":"Li","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology","place":["Guangzhou, China"]},{"name":"Jinan University","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris Zhiyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology","place":["Guangzhou, China"]},{"name":"Jinan University","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiu-Hong","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, The First Affiliated Hospital, Jiangxi Medical College","place":["Nanchang, China"]},{"name":"Nanchang University","place":["Nanchang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2025,12,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.61"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32004"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30566-7"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2020.11.017"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-021-02055-2"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdm195"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2015.143"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/nature10166"},{"issue":"3","key":"ref10\/cit10","first-page":"556","volume":"56","author":"Perego P.","year":"1996","journal-title":"Cancer Res."},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2019.100671"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0072609"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.68.7798"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-47080-3"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-022-00571-8"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01347-1"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-024-06965-3"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3380"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-020-0258-4"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3185"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-49986-4"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2025.09.014"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1322"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09234-6"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1093\/jmcb\/mjaa040"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2172"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2021.06.013"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkae030"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15449-9"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-018-1451-z"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-060410-105307"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.7150\/thno.29673"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2013.10.011"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.5c00657","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.5c00657","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T13:03:57Z","timestamp":1768568637000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.5c00657"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,16]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,2]]}},"alternative-id":["10.1021\/acs.jproteome.5c00657"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.5c00657","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,16]]}}}