{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T10:20:13Z","timestamp":1783074013634,"version":"3.54.6"},"reference-count":38,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100005045","name":"Ministry of Finance","doi-asserted-by":"publisher","award":["2025ZY01043"],"award-info":[{"award-number":["2025ZY01043"]}],"id":[{"id":"10.13039\/501100005045","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22277125"],"award-info":[{"award-number":["22277125"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82521004"],"award-info":[{"award-number":["82521004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U25A20594"],"award-info":[{"award-number":["U25A20594"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","award":["2023ZD0507800"],"award-info":[{"award-number":["2023ZD0507800"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDB1060000"],"award-info":[{"award-number":["XDB1060000"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2026,7,3]]},"DOI":"10.1021\/acs.jproteome.6c00285","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T17:38:16Z","timestamp":1780421896000},"page":"3730-3744","source":"Crossref","is-referenced-by-count":0,"title":["Comprehensive Proteomic Profiling Reveals Molecular Mechanisms Mediating Chemoradiotherapy Efficacy in Lung Cancer"],"prefix":"10.1021","volume":"25","author":[{"given":"Weiwei","family":"Ouyang","sequence":"first","affiliation":[{"name":"The Affiliated Hospital of Guizhou Medical University and the Affiliated Cancer Hospital of Guizhou Medical University, No.1 the west beijing road, Guiyang 550004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yixuan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica","place":["Nanjing, China"]},{"name":"Nanjing University of Chinese Medicine","place":["Nanjing, China"]},{"name":"State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica","place":["Shanghai, China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianghua","family":"Yang","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Guizhou Medical University and the Affiliated Cancer Hospital of Guizhou Medical University, No.1 the west beijing road, Guiyang 550004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongdong","family":"Cao","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Guizhou Medical University and the Affiliated Cancer Hospital of Guizhou Medical University, No.1 the west beijing road, Guiyang 550004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianjing","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Glyco-drug Research of Zhejiang Province, School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study","place":["Hangzhou, China"]},{"name":"University of Chinese Academy of Sciences","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxi","family":"Luo","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Guizhou Medical University and the Affiliated Cancer Hospital of Guizhou Medical University, No.1 the west beijing road, Guiyang 550004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Tian","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Guizhou Medical University and the Affiliated Cancer Hospital of Guizhou Medical University, No.1 the west beijing road, Guiyang 550004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6998-8131","authenticated-orcid":true,"given":"He","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica","place":["Nanjing, China"]},{"name":"Nanjing University of Chinese Medicine","place":["Nanjing, China"]},{"name":"State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica","place":["Shanghai, China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, China"]},{"name":"Key Laboratory of Glyco-drug Research of Zhejiang Province, School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study","place":["Hangzhou, China"]},{"name":"University of Chinese Academy of Sciences","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4923-7776","authenticated-orcid":true,"given":"Xinbo","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica","place":["Shanghai, China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"ref1\/cit1","unstructured":"World Health Organization. Lung Cancer Fact Sheet. World Health Organization, 2024. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/lung-cancer (accessed February 5, 2026)."},{"key":"ref2\/cit2","unstructured":"International Agency for Research\non Cancer (IARC). World Cancer\nReport: Cancer Research for Cancer Prevention. IARC, 2020. https:\/\/www.iarc.who.int\/featured-news\/new-world-cancer-report\/(accessed February 5, 2026)."},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-023-00798-3"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/prca.200800094"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-015-0419-y"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.21037\/ccts-20-171"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1593\/tlo.13535"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2140-0"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095-3941.2021.0690"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13153919"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-022-09717-8"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/iub.2043"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9124096"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-018-0008-0"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2025.5824"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr-22-633"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-025-02426-3"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpro.2023.100587"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1080\/14789450.2019.1559062"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15205005"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16081516"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-025-01710-5"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-07141-9"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-024-01831-4"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24033042"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.crmeth.2022.100288"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-019-0730-9"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-025-07262-7"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr.2017.09.07"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16244145"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-022-00879-y"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abk3338"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2025.144740"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.605097"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2024.01.012"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1186\/s40364-025-00859-y"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-025-03944-2"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.6c00285","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.6c00285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T09:49:49Z","timestamp":1783072189000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.6c00285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":38,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7,3]]}},"alternative-id":["10.1021\/acs.jproteome.6c00285"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.6c00285","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]}}}