{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T02:47:31Z","timestamp":1782269251291,"version":"3.54.5"},"reference-count":94,"publisher":"American Chemical Society (ACS)","issue":"10","funder":[{"DOI":"10.13039\/501100001403","name":"Indian Institute of Technology Kanpur","doi-asserted-by":"publisher","award":["IITK\/BSBE\/20100293"],"award-info":[{"award-number":["IITK\/BSBE\/20100293"]}],"id":[{"id":"10.13039\/501100001403","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2017,10,6]]},"DOI":"10.1021\/acs.jproteome.7b00491","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T09:31:17Z","timestamp":1504603877000},"page":"3863-3872","source":"Crossref","is-referenced-by-count":15,"title":["NMR Spectroscopy-based Metabolomics of <i>Drosophila<\/i> Model of Huntington\u2019s Disease Suggests Altered Cell Energetics"],"prefix":"10.1021","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6720-8784","authenticated-orcid":true,"given":"Virender","family":"Singh","sequence":"first","affiliation":[{"name":"Biological\rScience and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"Centre\rof Biomedical Research, SGPGIMS Campus, Lucknow 226014, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thamarailingam","family":"Athilingam","sequence":"additional","affiliation":[{"name":"Biological\rScience and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradip","family":"Sinha","sequence":"additional","affiliation":[{"name":"Biological\rScience and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3235-6127","authenticated-orcid":true,"given":"Neeraj","family":"Sinha","sequence":"additional","affiliation":[{"name":"Centre\rof Biomedical Research, SGPGIMS Campus, Lucknow 226014, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7268-6836","authenticated-orcid":true,"given":"Ashwani Kumar","family":"Thakur","sequence":"additional","affiliation":[{"name":"Biological\rScience and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2017,9,26]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2008.06310.x"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2013.05.003"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2014.24"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70245-3"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1326-1-19"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(87)90639-2"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(93)90168-K"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870110209"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.5.1357"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2000.0742108.x"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2005.03411.x"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2004.10.030"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/pr050244o"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl027"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2006.04323.x"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/pr900734g"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2011.08.001"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2015.12.001"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.6b00049"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2016.06.007"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/s11306-016-1084-8"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2016.06.002"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/srep20681"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0146480"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1089\/08977150152693683"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddg271"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1124\/pr.110.003293"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/npg.els.0005578"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgg.2011.09.003"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2016.05.010"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0500055102"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1326-8-35"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088681"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/11.10.1207"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/nature05128"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.09.025"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81200-3"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80573-5"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1126\/science.1062382"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2004.03.001"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/nature04779"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1126\/science.1067389"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0604661103"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.4161\/fly.26279"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2015.07.026"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0400243101"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1516217112"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.2174\/2213235X03666150108233830"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12215"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5459.1837"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/35099568"},{"key":"ref52\/cit52","first-page":"1711","volume":"105","author":"Dwivedi V.","year":"2013","journal-title":"Curr. Sci."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1242\/dev.120.8.2121","volume":"120","author":"Hay B. A.","year":"1994","journal-title":"Development"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1101\/pdb.prot066506"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2014.192"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.3791\/50245"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.mex.2014.07.002"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2011.366"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/ac5005103"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1039\/C5MB00386E"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.5b00919"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv380"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.5b00422"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/18.suppl_1.S105"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-7-142"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181ec173d"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.5936\/csbj.201301003"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81385-9"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.4238\/2012.August.6.4"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1308535110"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1326-7-20"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1016\/j.fob.2014.05.006"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601758"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e3181922348"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-015-0272-x"},{"key":"ref76\/cit76","first-page":"27","volume":"30","author":"Demarin V.","year":"2004","journal-title":"Drugs Exp. Clin. Res."},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv002"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2014.01.005"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1124\/pr.110.003905"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.12.004"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1126\/science.1098014"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1711.2003.t01-1-01177.x"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2007.11.011"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-016-0048-3"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2009.07.012"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0906039107"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1093\/bjaceaccp\/mkl018"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410410206"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199011000-00027"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/102054"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.05.035"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2011.05.024"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1021\/pr2000336"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-15-293"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.7b00491","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T14:01:28Z","timestamp":1682172088000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.7b00491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,26]]},"references-count":94,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10,6]]}},"alternative-id":["10.1021\/acs.jproteome.7b00491"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.7b00491","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,26]]}}}