{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:00:48Z","timestamp":1792670448579,"version":"4.5.0"},"reference-count":25,"publisher":"American Chemical Society (ACS)","issue":"3","funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K01 DK098285"],"award-info":[{"award-number":["K01 DK098285"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2018,3,2]]},"DOI":"10.1021\/acs.jproteome.7b00840","type":"journal-article","created":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T01:32:02Z","timestamp":1517880722000},"page":"1227-1234","source":"Crossref","is-referenced-by-count":16,"title":["Filter-Based Protein Digestion (FPD): A Detergent-Free and Scaffold-Based Strategy for TMT Workflows"],"prefix":"10.1021","volume":"17","author":[{"given":"Ekaterina","family":"Stepanova","sequence":"first","affiliation":[{"name":"Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven P.","family":"Gygi","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4291-413X","authenticated-orcid":true,"given":"Joao A.","family":"Paulo","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2018,2,13]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-6747-6_2"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/pr4010019"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/pr501266c"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/pr400032m"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.O115.049650"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0175967"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2017.06.019"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/ac702422x"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/ac0262560"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M400129-MCP200"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2011.09.009"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/pr2006318"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2016.07.005"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-016-1434-9"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0000000000000800"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201600319"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.5b00398"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201400155"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(82)90515-0"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.15386\/cjmed-367"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2015.05.020"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(01)00390-1"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1101\/gad.12.13.1962"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/C5MB00679A"},{"issue":"8","key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.4049\/jimmunol.143.8.2740","volume":"143","author":"Gomez-Marquez J.","year":"1989","journal-title":"J. Immunol"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.7b00840","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T17:48:23Z","timestamp":1681667303000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.7b00840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,13]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3,2]]}},"alternative-id":["10.1021\/acs.jproteome.7b00840"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.7b00840","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,13]]}}}