{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:00:53Z","timestamp":1792101653943,"version":"4.4.0"},"reference-count":71,"publisher":"American Chemical Society (ACS)","issue":"7","funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["NMRC-OF-IRG-0003-2016"],"award-info":[{"award-number":["NMRC-OF-IRG-0003-2016"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001459","name":"Ministry of Education - Singapore","doi-asserted-by":"publisher","award":["MOE2014-T2-2-043"],"award-info":[{"award-number":["MOE2014-T2-2-043"]}],"id":[{"id":"10.13039\/501100001459","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001459","name":"Ministry of Education - Singapore","doi-asserted-by":"publisher","award":["MOE2016-T2-2-018"],"award-info":[{"award-number":["MOE2016-T2-2-018"]}],"id":[{"id":"10.13039\/501100001459","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2018,7,6]]},"DOI":"10.1021\/acs.jproteome.8b00244","type":"journal-article","created":{"date-parts":[[2018,6,14]],"date-time":"2018-06-14T12:34:06Z","timestamp":1528979646000},"page":"2499-2510","source":"Crossref","is-referenced-by-count":39,"title":["Proteomic Analysis of Aqueous Humor from Primary Open Angle Glaucoma Patients on Drug Treatment Revealed Altered Complement Activation Cascade"],"prefix":"10.1021","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8559-4885","authenticated-orcid":true,"given":"Sunil S.","family":"Adav","sequence":"first","affiliation":[{"name":"School of Biological Sciences, Nanyang Technological University, Singapore 639798"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Wei","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Nanyang Technological University, Singapore 639798"},{"name":"Renmin Hospital of Wuhan University, Wuhan, Hubei 430072, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yap","family":"Terence","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Nanyang Technological University, Singapore 639798"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan C. H.","family":"Ang","sequence":"additional","affiliation":[{"name":"National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore 308433"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard W. L.","family":"Yip","sequence":"additional","affiliation":[{"name":"National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore 308433"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5652-1687","authenticated-orcid":true,"given":"Siu Kwan","family":"Sze","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Nanyang Technological University, Singapore 639798"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2018,6,14]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.05.013"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.06.004"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.85.10.1252"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2009.04.004"},{"issue":"1","key":"ref5\/cit5","first-page":"83","volume":"38","author":"Quigley H. A.","year":"1997","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2005.04.004"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1001\/archopthalmol.2011.1423"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2010.07.009"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2012.09.013"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1172\/JCI61135"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2017.05.004"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5289"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2012.08.010"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200404000-00003"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.10.036"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2009.06.005"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2010.10.002"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-016-0200-z"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/pr500754j"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-016-0272-9"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2005.00381.x"},{"key":"ref22\/cit22","first-page":"370","volume":"14","author":"Duan X.","year":"2008","journal-title":"Mol. Vis."},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5531"},{"key":"ref24\/cit24","first-page":"2839","volume":"16","author":"Duan X.","year":"2010","journal-title":"Mol. Vis."},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/pr1005372"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/pr4000762"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth1113"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq054"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1089\/omi.2015.0029"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-12858-7"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1126\/science.1141736"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3182934af6"},{"key":"ref33\/cit33","first-page":"293","volume":"13","author":"Khalyfa A.","year":"2007","journal-title":"Mol. Vis."},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-12941"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-018-0885-3"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1172\/JCI44646"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-016-0091-6"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(96)30749-5"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3181d12dd8"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1076\/ceyr.27.4.253.16603"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2013.12.006"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2011.10.017"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-20675"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)70059-5"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-200110001-00009"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057557"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2010.00149"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/nm1419"},{"key":"ref49\/cit49","first-page":"138","volume":"93","author":"Gewurz H.","year":"1993","journal-title":"Behring. Inst. Mitt."},{"issue":"6","key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.4049\/jimmunol.138.6.1871","volume":"138","author":"Peitsch M. C.","year":"1987","journal-title":"J. Immunol."},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2801-06.2006"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2014.02.004"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2015.08.015"},{"issue":"2","key":"ref54\/cit54","first-page":"431","volume":"41","author":"Johnson E. C.","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)01128-X"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2005.01.012"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(97)01139-9"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1016\/S0074-7742(07)82003-4"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2005.12.001"},{"key":"ref60\/cit60","first-page":"1437","volume":"14","author":"Grus F. H.","year":"2008","journal-title":"Mol. Vis."},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5531"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.6345"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201500423"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2015.08.006"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201200012"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1177\/1178641816686078"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0172481"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158611"},{"key":"ref69\/cit69","first-page":"451","volume":"21","author":"Soria J.","year":"2015","journal-title":"Mol. Vis."},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2013.1509"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2012.11.010"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.8b00244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T09:56:27Z","timestamp":1681638987000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.8b00244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,14]]},"references-count":71,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7,6]]}},"alternative-id":["10.1021\/acs.jproteome.8b00244"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.8b00244","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,14]]}}}