{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T15:13:57Z","timestamp":1779894837651,"version":"3.53.1"},"reference-count":64,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007721","name":"Cure SMA","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007721","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2019,8,2]]},"DOI":"10.1021\/acs.jproteome.9b00159","type":"journal-article","created":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T09:03:56Z","timestamp":1562058236000},"page":"3042-3051","source":"Crossref","is-referenced-by-count":8,"title":["Pathologic Alterations in the Proteome of Synaptosomes from a Mouse Model of Spinal Muscular Atrophy"],"prefix":"10.1021","volume":"18","author":[{"given":"Mehdi","family":"Eshraghi","sequence":"first","affiliation":[{"name":"Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada"},{"name":"University of Ottawa Centre for Neuromuscular Disease, Ottawa, Ontario K1H 8M5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Gombar","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario N9B 3P4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"De Repentigny","sequence":"additional","affiliation":[{"name":"Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2485-3505","authenticated-orcid":true,"given":"Panayiotis O.","family":"Vacratsis","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario N9B 3P4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Kothary","sequence":"additional","affiliation":[{"name":"Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada"},{"name":"University of Ottawa Centre for Neuromuscular Disease, Ottawa, Ontario K1H 8M5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,7,2]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.15.6.409"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90460-3"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)90847-8"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1995.00540290108025"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24864"},{"issue":"24","key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"4407","DOI":"10.1242\/jcs.114.24.4407","volume":"114","author":"Sleeman J. E.","year":"2001","journal-title":"J. Cell Sci."},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.8.1205"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/9.3.333"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm379"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm367"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2010.53.11.965"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e31821cbd8b"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4434-08.2009"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0026164"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/path.4080"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015457"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.12.032"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.09.011"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1172\/JCI71318"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq021"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddw278"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.171"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2017.01.019"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.211"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn923"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18-20-08300.1998"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.09.055"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201700460"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M500230-MCP200"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.4161\/cam.24803"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/iub.159"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-018-2849-1"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1086\/375039"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.08.027"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.737171"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.07.033"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1661"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA117.000490"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/pr9006987"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.211482"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.spen.2013.10.010"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddn133"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1111\/febs.14494"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2017-105012"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1042\/0264-6021:3580225"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1042\/bj3200345"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2012.05.003"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(99)00251-3"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.advenzreg.2010.09.008"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00640-8"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2462"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/cr200021m"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M402260200"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1110\/ps.8.12.2655"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2736(03)00024-5"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2014.00025"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/srep23787"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-11-04372.2002"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2011.07.007"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.01.035"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.45.26931"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1988.tb01124.x"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq385"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr065"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jproteome.9b00159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T08:40:55Z","timestamp":1682498455000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.9b00159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,2]]},"references-count":64,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8,2]]}},"alternative-id":["10.1021\/acs.jproteome.9b00159"],"URL":"https:\/\/doi.org\/10.1021\/acs.jproteome.9b00159","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,2]]}}}