{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T15:07:02Z","timestamp":1778771222530,"version":"3.51.4"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002865","name":"Chongqing Science and Technology Commission","doi-asserted-by":"publisher","award":["cstc2018jcyjAX0223"],"award-info":[{"award-number":["cstc2018jcyjAX0223"]}],"id":[{"id":"10.13039\/501100002865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81972439"],"award-info":[{"award-number":["81972439"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol. Pharmaceutics"],"published-print":{"date-parts":[[2022,7,4]]},"DOI":"10.1021\/acs.molpharmaceut.2c00174","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T02:40:30Z","timestamp":1651200030000},"page":"2418-2428","source":"Crossref","is-referenced-by-count":4,"title":["Multifunctional Nanoparticles Co-Loaded with Perfluoropropane, Indocyanine Green, and Methotrexate for Enhanced Multimodal Imaging of Collagen-Induced Arthritis"],"prefix":"10.1021","volume":"19","author":[{"given":"Xinyu","family":"He","sequence":"first","affiliation":[{"name":"Department of Pharmacy, First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China"},{"name":"Chongqing Key Laboratory of Ultrasound Molecular Imaging, Chongqing 400016, China"},{"name":"State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing 400016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanhuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2336-0864","authenticated-orcid":true,"given":"Shufang","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5739-5603","authenticated-orcid":true,"given":"Shenyin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2022,4,28]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra1004965"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kes113"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-0413-5"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/nature01661"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-209201"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204577"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2018.07.004"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2016.175"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210715"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.06.054"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1080\/03009742.2020.1794028"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/art.38175"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207345"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2015.02.052"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq012"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.12.037"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1007\/s40204-020-00139-y"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.2147\/ijn.s120902"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2015.06.024"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1117\/1.jbo.17.11.116025"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.2147\/ijn.s243548"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.2147\/ijn.s187929"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/mp100301t"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.2147\/ijn.s208404"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.7150\/thno.9754"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b12689"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201301655"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201800049"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1084\/jem.146.3.857"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.07.057"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1039\/c8nr00044a"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.01.054"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119520"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b03439"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.7150\/thno.44865"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2018.1507062"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/s0939-6411(03)00193-0"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/art.27542"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1148\/122.1.71"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.02.006"}],"container-title":["Molecular Pharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.molpharmaceut.2c00174","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.molpharmaceut.2c00174","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T08:23:27Z","timestamp":1682411007000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.molpharmaceut.2c00174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,28]]},"references-count":40,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7,4]]}},"alternative-id":["10.1021\/acs.molpharmaceut.2c00174"],"URL":"https:\/\/doi.org\/10.1021\/acs.molpharmaceut.2c00174","relation":{},"ISSN":["1543-8384","1543-8392"],"issn-type":[{"value":"1543-8384","type":"print"},{"value":"1543-8392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,28]]}}}