{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:09:05Z","timestamp":1788307745221,"version":"build-2803163510"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"9","license":[{"start":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T00:00:00Z","timestamp":1660867200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T00:00:00Z","timestamp":1660867200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T00:00:00Z","timestamp":1660867200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100008510","name":"University of Maryland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008510","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Skaggs Institute for Chemical Biology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol. Pharmaceutics"],"published-print":{"date-parts":[[2022,9,5]]},"DOI":"10.1021\/acs.molpharmaceut.2c00489","type":"journal-article","created":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T11:59:05Z","timestamp":1660910345000},"page":"3358-3366","source":"Crossref","is-referenced-by-count":12,"title":["Polyphosphazene: A New Adjuvant Platform for Cocaine Vaccine Development"],"prefix":"10.1021","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3325-4539","authenticated-orcid":true,"given":"Mingliang","family":"Lin","sequence":"first","affiliation":[{"name":"Departments of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Marin","sequence":"additional","affiliation":[{"name":"Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland 20850, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6876-1576","authenticated-orcid":true,"given":"Beverly","family":"Ellis","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5288-6294","authenticated-orcid":true,"given":"Lisa M.","family":"Eubanks","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6186-6156","authenticated-orcid":true,"given":"Alexander K.","family":"Andrianov","sequence":"additional","affiliation":[{"name":"Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland 20850, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6759-4227","authenticated-orcid":true,"given":"Kim D.","family":"Janda","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,8,19]]},"reference":[{"key":"ref1\/cit1","unstructured":"World Drug Report 2021. Sales No. E.21.XI.8; United Nations Publication, 2021."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aax1532"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12115"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0239780"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2014.04.003"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/jm400228w"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-021-01210-1"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2019.04.055"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0000000000000868"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.7b00933"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.07.085"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2016.03.028"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.0c00837"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.08.028"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2012.0536"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.06.121"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.6b01251"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.03.031"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.0c00189"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.12.001"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.625482"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2021.102359"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiw059"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-018-2929-4"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2012.03.026"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.0c00487"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2021.1875763"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b03334"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1111\/j.0818-9641.2004.01272.x"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2017.1365995"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1111\/1348-0421.12658"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2017.1349584"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/bm049745d"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/bm050790a"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(83)92046-3"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-015-9223-z"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2008.11.001"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/s41541-018-0094-0"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-4328(99)00036-0"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.10.011"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1086\/317537"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.4161\/hv.26109"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2005.07.006"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-014-1419-y"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00250-09"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1186\/1476-8518-8-4"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(00)00309-1"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2019.01.058"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s41541-021-00329-0"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41541-020-0161-1"}],"container-title":["Molecular Pharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.molpharmaceut.2c00489","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.molpharmaceut.2c00489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T14:46:42Z","timestamp":1682520402000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.molpharmaceut.2c00489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,19]]},"references-count":50,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9,5]]}},"alternative-id":["10.1021\/acs.molpharmaceut.2c00489"],"URL":"https:\/\/doi.org\/10.1021\/acs.molpharmaceut.2c00489","relation":{},"ISSN":["1543-8384","1543-8392"],"issn-type":[{"value":"1543-8384","type":"print"},{"value":"1543-8392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,19]]}}}