{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:40:55Z","timestamp":1792201255454,"version":"4.4.0"},"reference-count":51,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA237569"],"award-info":[{"award-number":["R01CA237569"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R37CA234006"],"award-info":[{"award-number":["R37CA234006"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009612","name":"Oregon State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009612","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol. Pharmaceutics"],"published-print":{"date-parts":[[2022,12,5]]},"DOI":"10.1021\/acs.molpharmaceut.2c00738","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T21:44:41Z","timestamp":1669067081000},"page":"4696-4704","source":"Crossref","is-referenced-by-count":27,"title":["Poly(aspartic acid)-Based Polymeric Nanoparticle for Local and Systemic mRNA Delivery"],"prefix":"10.1021","volume":"19","author":[{"given":"Youngrong","family":"Park","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham S.","family":"Moses","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananiya A.","family":"Demessie","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prem","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyelim","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetiana","family":"Korzun","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olena R.","family":"Taratula","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam W. G.","family":"Alani","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6227-9110","authenticated-orcid":true,"given":"Oleh","family":"Taratula","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Portland, Oregon 97239, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,11,21]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-022-01294-2"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-021-00283-5"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2017.243"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.113930"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-01007-w"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpclett.1c03898"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.8b00134"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.0c00618"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c04996"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2017.56"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.202000099"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c00997"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2020.06.014"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/am506730t"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.12.031"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.7150\/thno.27847"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.07.019"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2009.11.072"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/srep15810"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.10.042"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2012.20"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1089\/nat.2018.0721"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3330"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.1c00601"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-020-0669-6"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.03.046"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)82209-1"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemmater.6b01280"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-014-0131-x"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/mp400397t"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201608450"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2013.09.032"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.200600008"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3302945"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056220"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.06.001"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/ja804561g"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.120780"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.mlblux.2021.100066"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2006.04.014"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-009-9116-1"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b04246"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2010.85"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b02917"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.7b01356"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2017.04.006"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201801151"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c08268"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2109256118"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02441-2"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2021.12.008"}],"container-title":["Molecular Pharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.molpharmaceut.2c00738","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.molpharmaceut.2c00738","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T06:00:57Z","timestamp":1682488857000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.molpharmaceut.2c00738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,21]]},"references-count":51,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12,5]]}},"alternative-id":["10.1021\/acs.molpharmaceut.2c00738"],"URL":"https:\/\/doi.org\/10.1021\/acs.molpharmaceut.2c00738","relation":{},"ISSN":["1543-8384","1543-8392"],"issn-type":[{"value":"1543-8384","type":"print"},{"value":"1543-8392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,21]]}}}