{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T03:18:26Z","timestamp":1789442306698,"version":"build-2803163510"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T00:00:00Z","timestamp":1679529600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T00:00:00Z","timestamp":1679529600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T00:00:00Z","timestamp":1679529600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["201706275039"],"award-info":[{"award-number":["201706275039"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81402882"],"award-info":[{"award-number":["81402882"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol. Pharmaceutics"],"published-print":{"date-parts":[[2023,4,3]]},"DOI":"10.1021\/acs.molpharmaceut.2c00842","type":"journal-article","created":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T16:37:31Z","timestamp":1679589451000},"page":"1951-1963","source":"Crossref","is-referenced-by-count":38,"title":["Dual-Ligand-Functionalized Liposomes Based on Glycyrrhetinic Acid and cRGD for Hepatocellular Carcinoma Targeting and Therapy"],"prefix":"10.1021","volume":"20","author":[{"given":"Mingxing","family":"Qiu","sequence":"first","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiong","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"},{"name":"Wuhan Grand Hoyo Pharmaceutical Co., Ltd., Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaojiao","family":"Bai","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxu","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuiqing","family":"Tian","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoran","family":"Zheng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew R.","family":"Clark","sequence":"additional","affiliation":[{"name":"Indiana Center for Regenerative Medicine & Engineering, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinwei","family":"Cheng","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Liao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6876-730X","authenticated-orcid":true,"given":"Song","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5981-5867","authenticated-orcid":true,"given":"Robert J.","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0797-1312","authenticated-orcid":true,"given":"Xiaoju","family":"Zhou","sequence":"additional","affiliation":[{"name":"Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,3,23]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13864"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.4155\/tde-2015-0008"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.2741\/4734"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/srep23269"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3109\/10717544.2014.945018"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S33965"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2019.1636422"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2009.07.030"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2008.07.021"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.01.055"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2017.12.048"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.09.105"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2017.04.006"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24183332"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/srep44210"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.9b01580"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2018.11.082"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2010.06.029"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2018.2467"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2018.2638"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.02.042"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3109\/10717544.2014.977460"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2013.08.193"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S240359"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2020.06.017"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.01.006"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.10.012"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2018.11.023"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2021.1928794"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.2c02683"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2021.12611"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2010.08.054"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S188971"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2020.06.017"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2004.04.030"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2016.04.001"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2010.05.001"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00046"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.03.012"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.4202"}],"container-title":["Molecular Pharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.molpharmaceut.2c00842","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.molpharmaceut.2c00842","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T08:39:22Z","timestamp":1680511162000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.molpharmaceut.2c00842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,23]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4,3]]}},"alternative-id":["10.1021\/acs.molpharmaceut.2c00842"],"URL":"https:\/\/doi.org\/10.1021\/acs.molpharmaceut.2c00842","relation":{},"ISSN":["1543-8384","1543-8392"],"issn-type":[{"value":"1543-8384","type":"print"},{"value":"1543-8392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,23]]}}}