{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T03:53:56Z","timestamp":1788839636594,"version":"build-2803163510"},"reference-count":65,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/S013768\/1"],"award-info":[{"award-number":["EP\/S013768\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/S513829\/1"],"award-info":[{"award-number":["EP\/S513829\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000777","name":"University of Leeds","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000777","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Org. Process Res. Dev."],"published-print":{"date-parts":[[2024,5,17]]},"DOI":"10.1021\/acs.oprd.4c00012","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T18:43:37Z","timestamp":1715021017000},"page":"1979-1989","source":"Crossref","is-referenced-by-count":11,"title":["A Coalescing Filter for Liquid\u2013Liquid Separation and Multistage Extraction in Continuous-Flow Chemistry"],"prefix":"10.1021","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6148-4035","authenticated-orcid":true,"given":"James","family":"Daglish","sequence":"first","affiliation":[{"name":"School of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4898-2712","authenticated-orcid":true,"given":"A. John","family":"Blacker","sequence":"additional","affiliation":[{"name":"School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5647-1771","authenticated-orcid":true,"given":"Gregory","family":"de Boer","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Russell","sequence":"additional","affiliation":[{"name":"School of Design, University of Leeds, Leeds LS2 9JT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Tausif","sequence":"additional","affiliation":[{"name":"School of Design, University of Leeds, Leeds LS2 9JT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3872-7996","authenticated-orcid":true,"given":"David R. J.","family":"Hose","sequence":"additional","affiliation":[{"name":"Chemical Development, Pharmaceutical Technology and Development, Operations, AstraZeneca, Macclesfield SK10 2NA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna R.","family":"Parsons","sequence":"additional","affiliation":[{"name":"Chemical Development, Pharmaceutical Technology and Development, Operations, AstraZeneca, Macclesfield SK10 2NA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Crampton","sequence":"additional","affiliation":[{"name":"Chemical Development, Pharmaceutical Technology and Development, Operations, AstraZeneca, Macclesfield SK10 2NA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1041-8390","authenticated-orcid":true,"given":"Nikil","family":"Kapur","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,5,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00830E"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00183"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/c0sc00381f"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.coche.2019.07.007"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.9b00491"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.0c00079"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/op400294z"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2019.123340"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1126\/science.aax1566"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1126\/science.aat0650"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2009.05.042"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1039\/D1RE00205H"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.6b00234"},{"key":"ref14\/cit14","volume-title":"Industrial Separation Processes: Fundamentals","author":"Andr\u00e9 B. D. H.","year":"2013"},{"key":"ref15\/cit15","volume-title":"Ullmann\u2019s Encyclopedia of Industrial Chemistry","author":"Ullmann F.","year":"1996","edition":"5"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.9b05954"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ces.2017.03.023"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1556\/1846.2016.00024"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.7b01712"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.6b00226"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1556\/jfchem.2011.00017"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/c2ob25912e"},{"key":"ref23\/cit23","unstructured":"Syrris\nAsia FLLEX (Flow Liquid\u2013Liquid EXtraciton) module. https:\/\/syrris.com\/modules\/asia-fllex-flow-liquid-liquid-extraction\/."},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/ie401180t"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2003.10.025"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1515\/gps-2013-0006"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1039\/C9RE00144A"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1039\/D1RE00119A"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2015.08.028"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2016.02.083"},{"key":"ref31\/cit31","unstructured":"Zaiput\nliquid\u2013liquid\u2013gas separator. https:\/\/www.zaiput.com\/product\/liquid-liquid-gas-separators\/."},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/i160032a005"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2011.01.134"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.rineng.2019.100048"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/ie3026967"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/ie4018995"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2011.10.004"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2013.01.001"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/ie404013e"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2014.02.009"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2019.116254"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2016.02.006"},{"key":"ref43\/cit43","volume-title":"Handbook of Nonwovens","author":"Russell S. J.","year":"2007"},{"key":"ref44\/cit44","volume-title":"Handbook of Nonwoven Filter Media","author":"Hutten I. M.","year":"2007","edition":"1"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2021.110840"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.7b00173"},{"key":"ref47\/cit47","unstructured":"Beauregard, B. Improving the beginners PID. http:\/\/brettbeauregard.com\/blog\/2011\/04\/improving-the-beginners-pid-introduction\/ (accessed 14th March 2021)."},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/am502398u"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.6b00225"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.6b03384"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.14.52"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2015.08.028"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.7b00434"},{"key":"ref54\/cit54","author":"M\u00edsek T.","year":"1985","journal-title":"Institution of Chemical Engineers"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.2c00357"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.2118\/7054-PA"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.5b00382"},{"key":"ref58\/cit58","volume-title":"Surfactant Science: Principles and Practice","author":"Abbott S. J.","year":"2017"},{"key":"ref59\/cit59","volume-title":"Handbook of Industrial Mixing","author":"Paul E. L.","year":"2004"},{"key":"ref60\/cit60","unstructured":"HSDB.\nToluene. Hazardous Substances Data Bank, National Library of Medicine. 2010 http:\/\/toxnet.nlm.nih.gov. April 24, 2014."},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-019-06345-x"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.desal.2008.05.006"},{"key":"ref63\/cit63","doi-asserted-by":"crossref","DOI":"10.1201\/9780203021460","volume-title":"Solvent Extraction Principles and Practice, Revised and Expanded","author":"Rydberg J.","year":"2004"},{"key":"ref64\/cit64","unstructured":"Power, L. A. The continuous extraction of carboxylic acids and amines. PhD thesis, University of Leeds. 2022."},{"key":"ref65\/cit65","unstructured":"Sinnott, R.; Towler, G. Chemical Engineering Design: SI ed.; Butterworth-Heinemann: Oxford, 2019; p591."}],"container-title":["Organic Process Research & Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.oprd.4c00012","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.oprd.4c00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T15:23:13Z","timestamp":1716218593000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.oprd.4c00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,6]]},"references-count":65,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,17]]}},"alternative-id":["10.1021\/acs.oprd.4c00012"],"URL":"https:\/\/doi.org\/10.1021\/acs.oprd.4c00012","relation":{},"ISSN":["1083-6160","1520-586X"],"issn-type":[{"value":"1083-6160","type":"print"},{"value":"1520-586X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,6]]}}}