{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T07:09:40Z","timestamp":1790579380392,"version":"4.1.0"},"reference-count":22,"publisher":"American Chemical Society (ACS)","issue":"25","license":[{"start":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T00:00:00Z","timestamp":1655596800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T00:00:00Z","timestamp":1655596800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T00:00:00Z","timestamp":1655596800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001823","name":"Ministerstvo ?kolstv?, Ml?de?e a Telov?chovy","doi-asserted-by":"publisher","award":["MSM0021620857"],"award-info":[{"award-number":["MSM0021620857"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001824","name":"Grantov? 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The key synthetic sequence consists of a tandem anionic ketone allylation\/oxy-Cope rearrangement\/\u03b1-oxygenation furnishing an \u03b1-aminoxy ketone and a persistent radical effect-based 5-exo-trig cyclization leading to the trisubstituted cyclopentane core. The relative configuration of applanatumol V has to be revised. Some compounds display significant cytotoxic and antioxidant properties.<\/jats:p>","DOI":"10.1021\/acs.orglett.2c01633","type":"journal-article","created":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T07:43:51Z","timestamp":1655624631000},"page":"4552-4556","source":"Crossref","is-referenced-by-count":24,"title":["Unified Total Synthesis of Diverse Meroterpenoids\nfrom\n                    <i>Ganoderma Applanatum<\/i>"],"prefix":"10.1021","volume":"24","author":[{"given":"Michal","family":"S\u030cimek","sequence":"first","affiliation":[{"name":"Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences , Flemingovo na\u0301me\u030csti\u0301 2 , ,","place":["Prague\n6, Czech Republic, 16610"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kater\u030cina","family":"Ba\u0301rtova\u0301","sequence":"additional","affiliation":[{"name":"Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences , Flemingovo na\u0301me\u030csti\u0301 2 , ,","place":["Prague\n6, Czech Republic, 16610"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samy","family":"Issad","sequence":"additional","affiliation":[{"name":"Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences , Flemingovo na\u0301me\u030csti\u0301 2 , ,","place":["Prague\n6, Czech Republic, 16610"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Ha\u0301jek","sequence":"additional","affiliation":[{"name":"Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences , Flemingovo na\u0301me\u030csti\u0301 2 , ,","place":["Prague\n6, Czech Republic, 16610"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Ci\u0301sar\u030cova\u0301","sequence":"additional","affiliation":[{"name":"Charles University in Prague , , Hlavova 2030\/8 , ,","place":["Prague 2, Czech Republic, 12843"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8386-1348","authenticated-orcid":true,"given":"Ullrich","family":"Jahn","sequence":"additional","affiliation":[{"name":"Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences , Flemingovo na\u0301me\u030csti\u0301 2 , ,","place":["Prague\n6, Czech Republic, 16610"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,6,19]]},"reference":[{"key":"2026081712164760300_cit1","volume-title":"Ganoderma\nand Health: Pharmacology and Clinical Application","author":"Lin","year":"2019"},{"key":"2026081712164760300_cit2","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1016\/j.phytochem.2006.07.004","article-title":"Ganoderma-A therapeutic fungal biofactory","volume":"67","author":"Paterson","year":"2006","journal-title":"Phytochemistry"},{"key":"2026081712164760300_cit3","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.phytochem.2015.03.010","article-title":"Secondary\nmetabolites from Ganoderma","volume":"114","author":"Baby","year":"2015","journal-title":"Phytochemistry"},{"key":"2026081712164760300_cit4","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1021\/np990381y","article-title":"Ganomycins\nA and B, new antimicrobial farnesyl hydroquinones from the basidiomycete Ganoderma pfeifferi","volume":"63","author":"Mothana","year":"2000","journal-title":"J. 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