{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T04:49:21Z","timestamp":1793076561320,"version":"4.5.0"},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"49","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["2232015"],"award-info":[{"award-number":["2232015"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22471011"],"award-info":[{"award-number":["22471011"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["20230484447"],"award-info":[{"award-number":["20230484447"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]},{"name":"School of Chemistry and Chemical Engineering, Henan Normal University","award":["2024Z02"],"award-info":[{"award-number":["2024Z02"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Org. Lett."],"published-print":{"date-parts":[[2025,12,12]]},"DOI":"10.1021\/acs.orglett.5c04479","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T06:42:08Z","timestamp":1764225728000},"page":"13585-13590","source":"Crossref","is-referenced-by-count":3,"title":["Pd-Catalyzed Asymmetric Allylic Alkylation of Carboxylic Acids for the Synthesis of Chiral Butenolidyl Ester Prodrugs and Peptide\u2013Drug Conjugates"],"prefix":"10.1021","volume":"27","author":[{"given":"Yue","family":"Ma","sequence":"first","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering","place":["Beijing, China"]},{"name":"Beijing University of Chemical Technology","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfei","family":"Ren","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering","place":["Beijing, China"]},{"name":"Beijing University of Chemical Technology","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Congman","family":"Song","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering","place":["Xinxiang, China"]},{"name":"Henan Normal University","place":["Xinxiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiqing","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering","place":["Xinxiang, China"]},{"name":"Henan Normal University","place":["Xinxiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1856-6323","authenticated-orcid":true,"given":"Duanyang","family":"Kong","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering","place":["Beijing, China"]},{"name":"Beijing University of Chemical Technology","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"ref1\/cit1a","doi-asserted-by":"publisher","DOI":"10.1039\/9781849731102-00099"},{"key":"ref1\/cit1b","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-17841-1"},{"key":"ref1\/cit1c","doi-asserted-by":"publisher","DOI":"10.2174\/0929867328666210820112126"},{"key":"ref2\/cit2a","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2016.10.061"},{"key":"ref2\/cit2b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b01963"},{"key":"ref3\/cit3a","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c01444"},{"key":"ref3\/cit3b","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2004.02.006"},{"key":"ref3\/cit3c","first-page":"657","volume-title":"The practice of medicinal chemistry","author":"Wermuth C. G.","year":"2015","edition":"2"},{"key":"ref3\/cit3d","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/B978-0-12-374194-3.00036-6","volume-title":"The practice of medicinal chemistry","author":"Wermuth C. G.","year":"2008","edition":"2"},{"key":"ref3\/cit3e","doi-asserted-by":"publisher","DOI":"10.1208\/ps020106"},{"key":"ref3\/cit3f","doi-asserted-by":"publisher","DOI":"10.1038\/182421a0"},{"key":"ref3\/cit3g","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-52793-6"},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2018.46"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2468"},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514859"},{"key":"ref5\/cit5b","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)92785-1"},{"key":"ref5\/cit5c","doi-asserted-by":"publisher","DOI":"10.1007\/BF03261917"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/chir.530040513"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/S1734-1140(13)70959-9"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09445-x"},{"key":"ref9\/cit9a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201912926"},{"key":"ref9\/cit9b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202012445"},{"key":"ref9\/cit9c","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.3c01915"},{"key":"ref9\/cit9d","doi-asserted-by":"publisher","DOI":"10.1002\/cjoc.202400382"},{"key":"ref9\/cit9e","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202402909"},{"key":"ref10\/cit10a","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.04.025"},{"key":"ref10\/cit10b","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-00904-4"},{"key":"ref11\/cit11a","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24010829"},{"key":"ref11\/cit11b","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-025-03277-2"},{"key":"ref11\/cit11c","doi-asserted-by":"publisher","DOI":"10.1071\/CH22252"},{"key":"ref11\/cit11d","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2015.116"},{"key":"ref11\/cit11e","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.27419"},{"key":"ref11\/cit11f","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2022.09.016"},{"key":"ref11\/cit11g","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26102943"},{"key":"ref11\/cit11h","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.4c00106"},{"key":"ref11\/cit11i","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering12050481"},{"key":"ref11\/cit11j","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.0c01530"},{"key":"ref11\/cit11k","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.07.020"},{"key":"ref11\/cit11l","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-023-00850-2"},{"key":"ref12\/cit12a","doi-asserted-by":"publisher","DOI":"10.1039\/D3CC00568B"},{"key":"ref12\/cit12b","doi-asserted-by":"publisher","DOI":"10.1021\/ja020988s"},{"key":"ref12\/cit12c","doi-asserted-by":"publisher","DOI":"10.1021\/ja806278e"},{"key":"ref12\/cit12d","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200602169"},{"key":"ref12\/cit12e","doi-asserted-by":"publisher","DOI":"10.1021\/cs3007878"},{"key":"ref12\/cit12f","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.4c04209"},{"key":"ref12\/cit12g","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.1c04546"}],"container-title":["Organic Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.orglett.5c04479","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.orglett.5c04479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T09:16:03Z","timestamp":1765530963000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.orglett.5c04479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,27]]},"references-count":46,"journal-issue":{"issue":"49","published-print":{"date-parts":[[2025,12,12]]}},"alternative-id":["10.1021\/acs.orglett.5c04479"],"URL":"https:\/\/doi.org\/10.1021\/acs.orglett.5c04479","relation":{},"ISSN":["1523-7060","1523-7052"],"issn-type":[{"value":"1523-7060","type":"print"},{"value":"1523-7052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,27]]}}}