{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:28:09Z","timestamp":1789061289793,"version":"build-2803163510"},"reference-count":73,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100016807","name":"Natural Science Foundation of Shenyang Municipality","doi-asserted-by":"publisher","award":["23-503-6-10"],"award-info":[{"award-number":["23-503-6-10"]}],"id":[{"id":"10.13039\/100016807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["2222011"],"award-info":[{"award-number":["2222011"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22077074"],"award-info":[{"award-number":["22077074"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Org. Lett."],"published-print":{"date-parts":[[2026,1,30]]},"DOI":"10.1021\/acs.orglett.5c05246","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T14:48:23Z","timestamp":1768488503000},"page":"1399-1406","source":"Crossref","is-referenced-by-count":3,"title":["Development of Axially Chiral Phosphoramidite Ligands and Their Application in Pd-Catalyzed Asymmetric Synthesis of Spiro-Pyrazolone\u2013Pyrrolidinones via [2 + 3] Cycloaddition"],"prefix":"10.1021","volume":"28","author":[{"given":"Zhengyi","family":"Yi","sequence":"first","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, China"]},{"name":"Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, China"]},{"name":"Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weixin","family":"Xiao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, China"]},{"name":"Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lunyu","family":"Ou","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, China"]},{"name":"Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyun","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, China"]},{"name":"Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijun","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, China"]},{"name":"Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7250-0053","authenticated-orcid":true,"given":"Hua","family":"Fu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, China"]},{"name":"Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,1,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.2174\/1386207043328544"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2445"},{"key":"ref3\/cit3a","doi-asserted-by":"publisher","DOI":"10.1080\/10286020.2011.628316"},{"key":"ref3\/cit3b","doi-asserted-by":"publisher","DOI":"10.2174\/1385272819666140407213209"},{"key":"ref3\/cit3c","doi-asserted-by":"publisher","DOI":"10.1039\/C3OB42181C"},{"key":"ref3\/cit3d","doi-asserted-by":"publisher","DOI":"10.1039\/C6OB01349J"},{"key":"ref3\/cit3e","doi-asserted-by":"publisher","DOI":"10.2174\/0113852728264028230919060328"},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1111\/j.1527-3458.2001.tb00206.x"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2006.02.004"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.11.059"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2010.493558"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/24.12.2161"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa073275"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa073255"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.111006391.x"},{"key":"ref11\/cit11a","doi-asserted-by":"publisher","DOI":"10.1039\/D1RA01170G"},{"key":"ref11\/cit11b","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25081963"},{"key":"ref11\/cit11c","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.0c00829"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/cr020033s"},{"key":"ref13\/cit13a","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2009.02.113"},{"key":"ref13\/cit13b","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2005.09.017"},{"key":"ref13\/cit13c","doi-asserted-by":"publisher","DOI":"10.2174\/138527211795378263"},{"key":"ref13\/cit13d","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.08.057"},{"key":"ref13\/cit13e","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2007.12.009"},{"key":"ref13\/cit13f","doi-asserted-by":"publisher","DOI":"10.1111\/j.1527-3458.2006.00009.x"},{"key":"ref13\/cit13g","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2004.12.001"},{"key":"ref13\/cit13h","doi-asserted-by":"publisher","DOI":"10.2174\/157340707780809554"},{"key":"ref14\/cit14a","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1589030"},{"key":"ref14\/cit14b","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.7b00320"},{"key":"ref14\/cit14c","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.8b02188"},{"key":"ref14\/cit14d","doi-asserted-by":"publisher","DOI":"10.1039\/C8OB02675K"},{"key":"ref14\/cit14e","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.8b02188"},{"key":"ref14\/cit14f","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b02927"},{"key":"ref14\/cit14g","doi-asserted-by":"publisher","DOI":"10.1039\/D0NJ05915C"},{"key":"ref14\/cit14h","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.1c01215"},{"key":"ref14\/cit14i","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.3c02887"},{"key":"ref14\/cit14j","doi-asserted-by":"publisher","DOI":"10.1039\/D4OB00044G"},{"key":"ref14\/cit14k","doi-asserted-by":"publisher","DOI":"10.1039\/D5NJ00814J"},{"key":"ref14\/cit14l","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5c02700"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1039\/D4NJ02670E"},{"key":"ref16\/cit16a","doi-asserted-by":"publisher","DOI":"10.1021\/ar040063c"},{"key":"ref16\/cit16b","doi-asserted-by":"publisher","DOI":"10.1021\/cr400709j"},{"key":"ref16\/cit16c","doi-asserted-by":"publisher","DOI":"10.1021\/cs300771d"},{"key":"ref16\/cit16d","doi-asserted-by":"publisher","DOI":"10.1021\/cr400543u"},{"key":"ref16\/cit16e","doi-asserted-by":"publisher","DOI":"10.1021\/ja00307a059"},{"key":"ref16\/cit16f","doi-asserted-by":"publisher","DOI":"10.1021\/ja061662c"},{"key":"ref16\/cit16g","doi-asserted-by":"publisher","DOI":"10.1021\/ja0753389"},{"key":"ref16\/cit16h","doi-asserted-by":"publisher","DOI":"10.1021\/ja102102d"},{"key":"ref16\/cit16i","doi-asserted-by":"publisher","DOI":"10.1021\/ja073997f"},{"key":"ref16\/cit16j","doi-asserted-by":"publisher","DOI":"10.1021\/ja807662b"},{"key":"ref16\/cit16k","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201409467"},{"key":"ref16\/cit16l","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201711873"},{"key":"ref16\/cit16m","doi-asserted-by":"publisher","DOI":"10.1021\/ja801742h"},{"key":"ref16\/cit16n","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201509731"},{"key":"ref16\/cit16o","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b00462"},{"key":"ref16\/cit16p","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b08310"},{"key":"ref17\/cit17a","doi-asserted-by":"publisher","DOI":"10.1021\/ja309003x"},{"key":"ref17\/cit17b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.3c01883"},{"key":"ref17\/cit17c","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC00112A"},{"key":"ref17\/cit17d","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.3c00707"},{"key":"ref17\/cit17e","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.4c01315"},{"key":"ref17\/cit17f","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.4c01460"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5c01505"},{"key":"ref19\/cit19a","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201603706"},{"key":"ref19\/cit19b","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202500274"},{"key":"ref20\/cit20a","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2023.106344"},{"key":"ref20\/cit20b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5c04101"},{"key":"ref21\/cit21a","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b03230"},{"key":"ref21\/cit21b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b01631"},{"key":"ref21\/cit21c","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2018.11.018"},{"key":"ref21\/cit21d","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b04012"},{"key":"ref21\/cit21e","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b03382"},{"key":"ref21\/cit21f","doi-asserted-by":"publisher","DOI":"10.1039\/C9OB01057B"}],"container-title":["Organic Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.orglett.5c05246","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.orglett.5c05246","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T15:33:52Z","timestamp":1769787232000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.orglett.5c05246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,15]]},"references-count":73,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,1,30]]}},"alternative-id":["10.1021\/acs.orglett.5c05246"],"URL":"https:\/\/doi.org\/10.1021\/acs.orglett.5c05246","relation":{},"ISSN":["1523-7060","1523-7052"],"issn-type":[{"value":"1523-7060","type":"print"},{"value":"1523-7052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,15]]}}}