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This transformation operates under simple conditions, tolerates a wide range of functional groups, and renders these processes applicable to the late-stage functionalization of drugs. Preliminary mechanistic studies indicated that a single-electron transfer (SET) pathway is likely involved in this chalcogenation reaction.<\/jats:p>","DOI":"10.1021\/acs.orglett.6c02683","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:37:32Z","timestamp":1784306252000},"page":"9778-9782","source":"Crossref","is-referenced-by-count":1,"title":["Silver-Mediated\nRegioselective Pyridyl C(sp2)\u2013H Chalcogenation"],"prefix":"10.1021","volume":"28","author":[{"given":"Junlong","family":"Li","sequence":"first","affiliation":[{"name":"Chengdu University , , ,","place":["Chengdu, People\u2019s Republic of China, 610106"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianli","family":"Zhao","sequence":"additional","affiliation":[{"name":"Chengdu University , , ,","place":["Chengdu, People\u2019s Republic of China, 610106"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongrui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Chengdu University , , ,","place":["Chengdu, People\u2019s Republic of China, 610106"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Xue","sequence":"additional","affiliation":[{"name":"Chengdu University , , ,","place":["Chengdu, People\u2019s Republic of China, 610106"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6786-5947","authenticated-orcid":true,"given":"Linghui","family":"Gu","sequence":"additional","affiliation":[{"name":"Chengdu University , , ,","place":["Chengdu, People\u2019s Republic of China, 610106"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9690-3639","authenticated-orcid":true,"given":"Wenbo","family":"Ma","sequence":"additional","affiliation":[{"name":"Chengdu University , , ,","place":["Chengdu, People\u2019s Republic of China, 610106"]},{"name":"Chengdu University , , ,","place":["Chengdu, People\u2019s Republic of China, 610106"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,7,17]]},"reference":[{"key":"2026073109273219100_cit1a","doi-asserted-by":"publisher","first-page":"7166","DOI":"10.2174\/0929867325666180904125400","article-title":"Pyridine and pyrimidine derivatives as privileged scaffolds\nin biologically active agents","volume":"26","author":"Chiacchio","year":"2020","journal-title":"Curr. 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