{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T16:25:12Z","timestamp":1787415912145,"version":"build-2736575974"},"reference-count":74,"publisher":"American Chemical Society (ACS)","issue":"33","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100022955","name":"Fundamental Research Funds for the Provincial Universities of Zhejiang","doi-asserted-by":"publisher","award":["RF-B2023008"],"award-info":[{"award-number":["RF-B2023008"]}],"id":[{"id":"10.13039\/100022955","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","award":["2022C03169"],"award-info":[{"award-number":["2022C03169"]}],"id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","award":["2023C03117"],"award-info":[{"award-number":["2023C03117"]}],"id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22178315"],"award-info":[{"award-number":["22178315"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22378363"],"award-info":[{"award-number":["22378363"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22508112"],"award-info":[{"award-number":["22508112"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22578417"],"award-info":[{"award-number":["22578417"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"Natural Science Foundation of Huzhou City","doi-asserted-by":"publisher","award":["2025YZ01"],"award-info":[{"award-number":["2025YZ01"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"Central Government-Guided Funds for Local Science and Technology Development Projects","doi-asserted-by":"publisher","award":["2025ZY01073"],"award-info":[{"award-number":["2025ZY01073"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Functionalized ketones and alcohols are two privileged scaffolds widely found in natural products and biologically active compounds. They are also key synthetic intermediates in target-oriented synthesis. The divergent synthesis of ketones and alcohols from the same starting materials and catalysts via the borrowing hydrogen (BH) reaction is of great significance. Despite the significant advances in the divergent two-component alcohol transformation, recent catalytic systems show weaknesses in the selective cross-coupling of multicomponent alcohols, which can easily produce highly functionalized molecules. New, inexpensive, and readily available Fe catalysts were synthesized and successfully used for the cross-coupling of multicomponent alcohols. By regulating the reaction conditions, we achieved the divergent synthesis of \u03b2,\u03b2-methylated\/alkylated alcohols and \u03b1,\u03b1-methylated\/alkylated ketones with high selectivity. The use of readily available starting materials, low catalyst loading, broad substrate scope, ease of scale-up, and versatile functionalizations of the products make this approach highly practical and attractive.<\/jats:p>","DOI":"10.1021\/acs.orglett.6c02715","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T07:02:01Z","timestamp":1786431721000},"page":"10463-10468","source":"Crossref","is-referenced-by-count":0,"title":["Divergent Synthesis\nof Ketones and Alcohols via Iron-Catalyzed\nThree-Component Alcohol Cross-Coupling"],"prefix":"10.1021","volume":"28","author":[{"given":"Dingguo","family":"Song","sequence":"first","affiliation":[{"name":"Huzhou University , , ,","place":["Huzhou, P. R. China, 313000"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guan","family":"Wang","sequence":"additional","affiliation":[{"name":"Taizhou Vocational and Technical College , , ,","place":["Taizhou, P. R. China, 318000"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyuan","family":"Hu","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, P. R. China, 310014"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4274-912X","authenticated-orcid":true,"given":"Fei","family":"Ling","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, P. R. China, 310014"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0349-2226","authenticated-orcid":true,"given":"Weihui","family":"Zhong","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, P. R. China, 310014"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"2026082212105838100_cit1","doi-asserted-by":"publisher","first-page":"1722","DOI":"10.1021\/acs.accounts.8b00201","article-title":"The Xanthate\nRoute to Ketones: When the Radical Is Better than the Enolate","volume":"51","author":"Zard","year":"2018","journal-title":"Acc. Chem. Res."},{"key":"2026082212105838100_cit2a","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1021\/ar4002894","article-title":"Catalytic Conversion\nof Nonfood Woody\nBiomass Solids to Organic Liquids","volume":"47","author":"Barta","year":"2014","journal-title":"Acc. Chem.\nRes."},{"key":"2026082212105838100_cit2b","doi-asserted-by":"publisher","first-page":"5447","DOI":"10.1039\/D5GC06095H","article-title":"Mn-catalyzed\nhydroxyalkylation of \u03b1-trifluoromethylstyrenes with cyclopropanols:\nfacile synthesis of \u03b4-trifluoromethyl-\u03b4-hydroxyketones","volume":"28","author":"Deng","year":"2026","journal-title":"Green Chem."},{"key":"2026082212105838100_cit3","doi-asserted-by":"publisher","first-page":"1229712","DOI":"10.1126\/science.1229712","article-title":"Applications of Acceptorless Dehydrogenation and Related\nTransformations in Chemical Synthesis","volume":"341","author":"Gunanathan","year":"2013","journal-title":"Science"},{"key":"2026082212105838100_cit4","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1126\/science.1191843","article-title":"The Give and\nTake of Alcohol Activation","volume":"329","author":"Watson","year":"2010","journal-title":"Science"},{"key":"2026082212105838100_cit5a","doi-asserted-by":"publisher","first-page":"5541","DOI":"10.1039\/D3CS00424D","article-title":"Enantioconvergent transformations\nof secondary alcohols through borrowing hydrogen catalysis","volume":"52","author":"Gao","year":"2023","journal-title":"Chem. Soc. Rev."},{"key":"2026082212105838100_cit5b","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1021\/acscentsci.1c00125","article-title":"Borrowing Hydrogen\nfor Organic Synthesis","volume":"7","author":"Reed-Berendt","year":"2021","journal-title":"ACS Cent. Sci."},{"key":"2026082212105838100_cit5c","doi-asserted-by":"publisher","first-page":"12912","DOI":"10.1002\/chem.202001253","article-title":"Control of Absolute Stereochemistry in Transition-Metal-Catalysed\nHydrogen Borrowing Reactions","volume":"26","author":"Kwok","year":"2020","journal-title":"Chem.\u2500Eur.\nJ."},{"key":"2026082212105838100_cit5d","doi-asserted-by":"publisher","first-page":"2524","DOI":"10.1021\/acs.chemrev.8b00306","article-title":"3d-Metal Catalyzed N- and C-Alkylation Reactions via Borrowing\nHydrogen or Hydrogen Autotransfer","volume":"119","author":"Irrgang","year":"2019","journal-title":"Chem. Rev."},{"key":"2026082212105838100_cit5e","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.1021\/acs.chemrev.7b00340","article-title":"Advances in One-Pot\nSynthesis through Borrowing Hydrogen Catalysis","volume":"118","author":"Corma","year":"2018","journal-title":"Chem. Rev."},{"key":"2026082212105838100_cit5f","doi-asserted-by":"publisher","first-page":"9228","DOI":"10.1021\/acs.chemrev.6b00556","article-title":"Homogeneous Transition\nMetal Catalysis of Acceptorless Dehydrogenative Alcohol Oxidation:\nApplications in Hydrogen Storage and to Heterocycle Synthesis","volume":"117","author":"Crabtree","year":"2017","journal-title":"Chem. Rev."},{"key":"2026082212105838100_cit5g","doi-asserted-by":"publisher","first-page":"2305","DOI":"10.1039\/C4CS00496E","article-title":"Substitution of alcohols by N-nucleophiles via transition metal-catalyzed dehydrogenation","volume":"44","author":"Yang","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"2026082212105838100_cit5h","doi-asserted-by":"publisher","first-page":"11022","DOI":"10.1002\/anie.201503247","article-title":"Transition-Metal-Catalyzed\nHydrogen-Transfer Annulations: Access to Heterocyclic Scaffolds","volume":"54","author":"Nandakumar","year":"2015","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026082212105838100_cit5i","doi-asserted-by":"publisher","first-page":"9142","DOI":"10.1002\/anie.201403873","article-title":"Catalytic Enantioselective\nC-H Functionalization of Alcohols by Redox-Triggered Carbonyl Addition:\nBorrowing Hydrogen, Returning Carbon","volume":"53","author":"Ketcham","year":"2014","journal-title":"Angew.\nChem., Int. Ed."},{"key":"2026082212105838100_cit6a","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1002\/adsc.202101077","article-title":"Nickel-Catalyzed Selective\nSynthesis of \u03b1-Alkylated Ketones via Dehydrogenative Cross-Coupling\nof Primary and Secondary Alcohols","volume":"364","author":"Bains","year":"2022","journal-title":"Adv. Synth.\nCatal."},{"key":"2026082212105838100_cit6b","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1021\/acs.orglett.0c04098","article-title":"Selective Catalytic\nSynthesis of \u03b1-Alkylated Ketones and \u03b2-Disubstituted Ketones\nvia Acceptorless Dehydrogenative Cross-Coupling of Alcohols","volume":"23","author":"Bhattacharyya","year":"2021","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit6c","doi-asserted-by":"publisher","first-page":"2557","DOI":"10.1002\/cssc.202000576","article-title":"Sustainable and Selective Alkylation of Deactivated\nSecondary Alcohols to Ketones by Non-bifunctional Pincer N-heterocyclic\nCarbene Manganese","volume":"13","author":"Lan","year":"2020","journal-title":"ChemSusChem"},{"key":"2026082212105838100_cit6d","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1021\/acs.orglett.5c04659","article-title":"Nickel-Catalyzed Dehydrogenation-Condensation-Rehydrogenation\n(DCR) Approach toward the Synthesis of Branched Primary Alcohols","volume":"28","author":"Ghosh","year":"2026","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit6e","doi-asserted-by":"publisher","first-page":"10300","DOI":"10.1021\/acscatal.8b03720","article-title":"Manganese-Catalyzed \u03b1-Alkylation\nof Ketones, Esters, and Amides Using Alcohols","volume":"8","author":"Chakraborty","year":"2018","journal-title":"ACS Catal."},{"key":"2026082212105838100_cit6f","doi-asserted-by":"publisher","first-page":"14991","DOI":"10.1039\/C4CC06933A","article-title":"Selective ruthenium-catalyzed methylation of 2-arylethanols\nusing methanol as C1 feedstock","volume":"50","author":"Li","year":"2014","journal-title":"Chem. Commun."},{"key":"2026082212105838100_cit6g","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1002\/anie.201912055","article-title":"Manganese-Catalyzed\n\u03b2-Methylation of Alcohols by Methanol","volume":"59","author":"Schlagbauer","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026082212105838100_cit6h","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1007\/s11426-021-1017-0","article-title":"Highly efficient NHC-iridium-catalyzed \u03b2-methylation of alcohols\nwith methanol at low catalyst loadings","volume":"64","author":"Lu","year":"2021","journal-title":"Sci.\nChina: Chem."},{"key":"2026082212105838100_cit6i","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1002\/anie.201909035","article-title":"Manganese(I)-Catalyzed \u03b2-Methylation\nof Alcohols Using Methanol as C1 Source","volume":"59","author":"Kaithal","year":"2020","journal-title":"Angew.\nChem., Int. Ed."},{"key":"2026082212105838100_cit6j","doi-asserted-by":"publisher","first-page":"8575","DOI":"10.1021\/acscatal.9b02461","article-title":"Iron-Catalyzed Borrowing Hydrogen\n\u03b2-C(sp3)-Methylation of Alcohols","volume":"9","author":"Polidano","year":"2019","journal-title":"ACS Catal."},{"key":"2026082212105838100_cit6k","doi-asserted-by":"publisher","first-page":"3069","DOI":"10.1002\/cssc.201802689","article-title":"Manganese-Catalyzed Selective Upgrading of Ethanol with Methanol\ninto Isobutanol","volume":"12","author":"Liu","year":"2019","journal-title":"ChemSusChem"},{"key":"2026082212105838100_cit7a","doi-asserted-by":"publisher","first-page":"4753","DOI":"10.1039\/D2CY00759B","article-title":"Guerbet-type \u03b2-alkylation of\nsecondary alcohols catalyzed by\nchromium chloride and its corresponding NNN pincer complex","volume":"12","author":"Narjinari","year":"2022","journal-title":"Catal. Sci. Technol."},{"key":"2026082212105838100_cit7b","doi-asserted-by":"publisher","first-page":"10737","DOI":"10.1002\/chem.202101360","article-title":"A Proton-Responsive Pyridyl(benzamide)-Functionalized\nNHC Ligand on Ir Complex for Alkylation of Ketones and Secondary Alcohols","volume":"27","author":"Kaur","year":"2021","journal-title":"Chem.\u2500Eur. J."},{"key":"2026082212105838100_cit7c","doi-asserted-by":"publisher","first-page":"3320","DOI":"10.1021\/acs.orglett.1c00782","article-title":"Nickel-Catalyzed\nGuerbet Type Reaction: C-Alkylation of Secondary\nAlcohols via Double (de)Hydrogenation","volume":"23","author":"Babu","year":"2021","journal-title":"Org.\nLett."},{"key":"2026082212105838100_cit7d","doi-asserted-by":"publisher","first-page":"4750","DOI":"10.1021\/acs.orglett.7b02105","article-title":"Utilization of MeOH as a C1 Building\nBlock in Tandem Three-Component Coupling Reaction","volume":"19","author":"Chakrabarti","year":"2017","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit7e","doi-asserted-by":"publisher","first-page":"11408","DOI":"10.1002\/anie.202003104","article-title":"Asymmetric Guerbet\nReaction to Access Chiral Alcohols","volume":"59","author":"Wang","year":"2020","journal-title":"Angew. Chem.,\nInt. Ed."},{"key":"2026082212105838100_cit7f","doi-asserted-by":"publisher","first-page":"11384","DOI":"10.1002\/anie.202004758","article-title":"Room-Temperature Guerbet Reaction\nwith Unprecedented Catalytic Efficiency and Enantioselectivity","volume":"59","author":"Ng","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026082212105838100_cit7g","doi-asserted-by":"publisher","first-page":"3099","DOI":"10.1002\/cssc.201801660","article-title":"C-Alkylation\nof Secondary Alcohols by Primary Alcohols through Manganese-Catalyzed\nDouble Hydrogen Autotransfer","volume":"12","author":"ElSepelgy","year":"2019","journal-title":"ChemSusChem"},{"key":"2026082212105838100_cit7h","doi-asserted-by":"publisher","first-page":"7201","DOI":"10.1021\/acscatal.8b01960","article-title":"Manganese-Catalyzed\n\u03b2-Alkylation of Secondary Alcohols with Primary Alcohols under\nPhosphine-Free Conditions","volume":"8","author":"Liu","year":"2018","journal-title":"ACS Catal."},{"key":"2026082212105838100_cit7i","doi-asserted-by":"publisher","first-page":"12110","DOI":"10.1002\/chem.201701211","article-title":"Cobalt-Catalyzed Alkylation\nof Secondary Alcohols with Primary Alcohols via Borrowing Hydrogen\/Hydrogen\nAutotransfer","volume":"23","author":"Freitag","year":"2017","journal-title":"Chem.\u2500Eur. J."},{"key":"2026082212105838100_cit8a","doi-asserted-by":"publisher","first-page":"2390","DOI":"10.1021\/cr400215u","article-title":"Catalytic C\u2013C\nBond-Forming Multi Component Cascade or Domino Reactions: Pushing\nthe Boundaries of Complexity in Asymmetric Organocatalysis","volume":"114","author":"Volla","year":"2014","journal-title":"Chem. Rev."},{"key":"2026082212105838100_cit8b","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.gresc.2024.10.006","article-title":"Chemo- and diastereoselective four-component reactions with Rh carbynoids","volume":"6","author":"Zhang","year":"2025","journal-title":"Green Synth. Catal."},{"key":"2026082212105838100_cit9","doi-asserted-by":"publisher","first-page":"3057","DOI":"10.1021\/acs.orglett.9b00630","article-title":"Iron-Catalyzed\nTandem Three-Component Alkylation: Access to \u03b1-Methylated Substituted\nKetones","volume":"21","author":"Bettoni","year":"2019","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit10","doi-asserted-by":"publisher","first-page":"e202215882","DOI":"10.1002\/anie.202215882","article-title":"Manganese-Catalyzed Chemoselective\nCoupling of Secondary Alcohols, Primary Alcohols and Methanol","volume":"62","author":"Tang","year":"2023","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026082212105838100_cit11","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1039\/D3NJ05498E","article-title":"One-pot three-component synthesis of \u03b1-methylated\nketones from secondary and primary aryl alcohols","volume":"48","author":"Samser","year":"2024","journal-title":"New J. Chem."},{"key":"2026082212105838100_cit12a","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.1002\/anie.201611318","article-title":"Manganese-Catalyzed\nMulticomponent Synthesis of Pyrimidines from Alcohols and Amidines","volume":"56","author":"Deibl","year":"2017","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026082212105838100_cit12b","doi-asserted-by":"publisher","first-page":"12804","DOI":"10.1021\/jacs.5b09510","article-title":"A Sustainable Multicomponent\nPyrimidine Synthesis","volume":"137","author":"Deibl","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"2026082212105838100_cit13","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1039\/C6CS00247A","article-title":"Switchable\nDivergent Asymmetric Synthesis via Organocatalysis","volume":"46","author":"Zhan","year":"2017","journal-title":"Chem. Soc. Rev."},{"key":"2026082212105838100_cit14","doi-asserted-by":"publisher","first-page":"3567","DOI":"10.1039\/C9OB00418A","article-title":"Reaction\nCondition Controlled Nickel(II)-Catalyzed C\u2013C Cross-Coupling\nof Alcohols","volume":"17","author":"Zhang","year":"2019","journal-title":"Org. Biomol. Chem."},{"key":"2026082212105838100_cit15a","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1021\/acs.organomet.1c00147","article-title":"Switchable\n\u03b2-alkylation of Secondary Alcohols with Primary Alcohols by\na Well-Defined Cobalt Catalyst","volume":"40","author":"Pandey","year":"2021","journal-title":"Organometallics"},{"key":"2026082212105838100_cit15b","doi-asserted-by":"publisher","first-page":"7420","DOI":"10.1021\/acs.orglett.9b02727","article-title":"Selective Ketone Formations\nvia Cobalt-Catalyzed \u03b2-Alkylation of Secondary Alcohols with\nPrimary Alcohols","volume":"21","author":"Pandey","year":"2019","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit16","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1002\/cctc.201901871","article-title":"On the Mecha nism of\nthe Ruthenium-Catalyzed \u03b2-Methylation of Alcohols with Methanol","volume":"12","author":"Kaithal","year":"2020","journal-title":"ChemCatChem"},{"key":"2026082212105838100_cit17a","doi-asserted-by":"publisher","first-page":"2797","DOI":"10.1039\/C8CC10315A","article-title":"Aldehyde effect and ligand discovery in Ru-catalyzed dehydrogenative\ncross-coupling of alcohols to esters","volume":"55","author":"Jiang","year":"2019","journal-title":"Chem.\nCommun."},{"key":"2026082212105838100_cit17b","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1021\/acscatal.8b04585","article-title":"Dehydrogenative Cross-Coupling\nof Primary Alcohols to Form Cross-Esters Catalyzed by a Manganese\nPincer Complex","volume":"9","author":"Das","year":"2019","journal-title":"ACS Catal."},{"key":"2026082212105838100_cit17c","doi-asserted-by":"publisher","first-page":"4478","DOI":"10.1021\/acs.orglett.8b01775","article-title":"Cobalt-Catalyzed Acceptorless Dehydrogenative\nCoupling of Primary Alcohols to Esters","volume":"20","author":"Paudel","year":"2018","journal-title":"Org.\nLett."},{"key":"2026082212105838100_cit17d","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.1021\/acscatal.6b03554","article-title":"Manganese Pincer Complexes for the Base-Free, Acceptorless\nDehydrogenative Coupling of Alcohols to Esters: Development, Scope,\nand Understanding","volume":"7","author":"Nguyen","year":"2017","journal-title":"ACS Catal."},{"key":"2026082212105838100_cit17e","doi-asserted-by":"publisher","first-page":"3994","DOI":"10.1021\/cs5009656","article-title":"Well-Defined Iron Catalysts for the\nAcceptorless Reversible Dehydrogenation-Hydrogenation of Alcohols\nand Ketones","volume":"4","author":"Chakraborty","year":"2014","journal-title":"ACS Catal."},{"key":"2026082212105838100_cit18","doi-asserted-by":"publisher","first-page":"17487","DOI":"10.1021\/jacs.9b08832","article-title":"Direct Synthesis of Cycloalkanes\nfrom Diols and Secondary\nAlcohols or Ketones Using a Homogeneous Manganese Catalyst","volume":"141","author":"Kaithal","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"2026082212105838100_cit19","doi-asserted-by":"publisher","first-page":"9139","DOI":"10.1021\/acs.joc.0c01099","article-title":"Iridium-Catalyzed Alkylation of Secondary Alcohols\nwith Primary Alcohols: A Route to Access Branched Ketones and Alcohols","volume":"85","author":"Genc\u0327","year":"2020","journal-title":"J. Org. Chem."},{"key":"2026082212105838100_cit20a","doi-asserted-by":"publisher","first-page":"2345","DOI":"10.1002\/cssc.201900799","article-title":"Iron-Catalyzed Borrowing Hydrogen\nC-Alkylation of Oxindoles with Alcohols","volume":"12","author":"Dambatta","year":"2019","journal-title":"ChemSusChem"},{"key":"2026082212105838100_cit20b","doi-asserted-by":"publisher","first-page":"6440","DOI":"10.1021\/acscatal.8b02158","article-title":"Iron-Catalyzed\nMethylation Using the Borrowing Hydrogen Approach","volume":"8","author":"Polidano","year":"2018","journal-title":"ACS Catal."},{"key":"2026082212105838100_cit21","doi-asserted-by":"publisher","first-page":"14483","DOI":"10.1002\/anie.201506698","article-title":"Iron-Catalyzed\n\u03b1-Alkylation\nof Ketones with Alcohols","volume":"54","author":"Elangovan","year":"2015","journal-title":"Angew. Chem., Int.\nEd."},{"key":"2026082212105838100_cit22a","doi-asserted-by":"publisher","first-page":"2345","DOI":"10.1002\/cssc.201900799","article-title":"Iron-Catalyzed Borrowing Hydrogen\nC-Alkylation of Oxindoles with Alcohols","volume":"12","author":"Dambatta","year":"2019","journal-title":"ChemSusChem"},{"key":"2026082212105838100_cit22b","doi-asserted-by":"publisher","first-page":"6440","DOI":"10.1021\/acscatal.8b02158","article-title":"Iron-Catalyzed\nMethylation Using the Borrowing Hydrogen Approach","volume":"8","author":"Polidano","year":"2018","journal-title":"ACS Catal."},{"key":"2026082212105838100_cit23a","doi-asserted-by":"publisher","first-page":"4640","DOI":"10.1002\/adsc.201800924","article-title":"Bifunctional Iron Complexes Catalyzed Alkylation of\nIndoles","volume":"360","author":"Seck","year":"2018","journal-title":"Adv. Synth. Catal."},{"key":"2026082212105838100_cit23b","doi-asserted-by":"publisher","first-page":"8404","DOI":"10.1021\/acs.orglett.9b03171","article-title":"Iron-Catalyzed \u03b2-Alkylation\nof Alcohols","volume":"21","author":"Bettoni","year":"2019","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit23c","doi-asserted-by":"publisher","first-page":"2064","DOI":"10.1021\/acs.orglett.0c00549","article-title":"Iron-Catalyzed \u03b1-Alkylation\nof Ketones with Secondary Alcohols: Access to \u03b2-Disubstituted\nCarbonyl Compounds","volume":"22","author":"Bettoni","year":"2020","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit23d","doi-asserted-by":"publisher","first-page":"12909","DOI":"10.1039\/D0CC05840H","article-title":"A phosphine-free\niron complex-catalyzed synthesis of cycloalkanes via the borrowing\nhydrogen strategy","volume":"56","author":"Bettoni","year":"2020","journal-title":"Chem. Commun."},{"key":"2026082212105838100_cit23e","doi-asserted-by":"publisher","first-page":"5584","DOI":"10.1021\/acs.orglett.2c02233","article-title":"Blue-Light-Induced Iron-Catalyzed \u03b1-Alkylation\nof Ketones","volume":"24","author":"Abdallah","year":"2022","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit24","doi-asserted-by":"publisher","first-page":"6219","DOI":"10.1021\/acs.orglett.2c02545","article-title":"Iron-Catalyzed\n\u03b1-Methylation of Ketones Using Methanol as the C1 Source under\nPhotoirradiation","volume":"24","author":"Emayavaramban","year":"2022","journal-title":"Org. Lett."},{"key":"2026082212105838100_cit25","doi-asserted-by":"publisher","first-page":"16378","DOI":"10.1021\/acs.joc.2c02050","article-title":"Chemoselective\n\u03b1-Alkylation\nand \u03b1-Olefination of Arylacetonitriles with Alcohols via Iron-Catalyzed\nBorrowing Hydrogen and Dehydrogenative Coupling","volume":"87","author":"Putta","year":"2022","journal-title":"J. Org. Chem."},{"key":"2026082212105838100_cit26a","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1039\/D0QO01171A","article-title":"Ruthenium\ncatalyzed \u03b1-methylation of sulfones with methanol as a sustainable\nC1 source","volume":"8","author":"Song","year":"2021","journal-title":"Org. Chem. Front."},{"key":"2026082212105838100_cit26b","doi-asserted-by":"publisher","first-page":"6830","DOI":"10.1039\/D1QO01443A","article-title":"Design of chiral ferrocenylphosphine-spiro\nphosphonamidite ligands for ruthenium-catalyzed highly enantioselective\ncoupling of 1,2-diols with amines","volume":"8","author":"Yi","year":"2021","journal-title":"Org. Chem.\nFront."},{"key":"2026082212105838100_cit26c","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1039\/D2GC03679G","article-title":"Manganese catalyzed cross-coupling\nof allylic alcohols and nitriles: an elegant route for access to \u03b4-hydroxynitriles","volume":"25","author":"Wang","year":"2023","journal-title":"Green Chem."},{"key":"2026082212105838100_cit26d","doi-asserted-by":"publisher","first-page":"5908","DOI":"10.1039\/D3QO01220D","article-title":"Blue light\ninduced iron-catalyzed chemoselective \u03b1-alkylation and \u03b1-olefination\nof arylacetonitriles with alcohols","volume":"10","author":"Song","year":"2023","journal-title":"Org. Chem.\nFront."},{"key":"2026082212105838100_cit26e","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.1002\/adsc.202301219","article-title":"Room-temperature synthesis of \u03b1-alkylated indolin-2-ones via\na photo assisted iron catalyzed borrowing hydrogen reaction","volume":"366","author":"Song","year":"2024","journal-title":"Adv. Synth. Catal."},{"key":"2026082212105838100_cit27","doi-asserted-by":"publisher","first-page":"5976","DOI":"10.1021\/jacs.2c00638","article-title":"Methane Monooxygenase Mimic Asymmetric\nOxidation: Self-Assembling \u03bc-Hydroxo, Carboxylate-Bridged Diiron(III)-Catalyzed\nEnantioselective Dehydrogenation","volume":"144","author":"Guan","year":"2022","journal-title":"J. Am. Chem.\nSoc."},{"key":"2026082212105838100_cit28","doi-asserted-by":"publisher","first-page":"e202214633","DOI":"10.1002\/anie.202214633","article-title":"Trifluoromethylation\nof Carbonyl and Unactivated Olefin Derivatives by C(sp3)\u2013C Bond Cleavage","volume":"62","author":"Cong","year":"2023","journal-title":"Angew. Chem., Int.\nEd."},{"key":"2026082212105838100_cit29","doi-asserted-by":"publisher","first-page":"9316","DOI":"10.1002\/anie.201403983","article-title":"N-Trifluoromethylthiosaccharin: An\nEasily Accessible, Shelf-Stable, Broadly Applicable Trifluoromethylthiolating\nReagent","volume":"53","author":"Xu","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026082212105838100_cit30","doi-asserted-by":"publisher","first-page":"5028","DOI":"10.1021\/acs.orglett.1c01553","article-title":"Switchable\nCobalt-Catalyzed \u03b1-Olefination and\n\u03b1-Alkylation of Nitriles with Primary Alcohols","volume":"23","author":"Paudel","year":"2021","journal-title":"Org. Lett."}],"container-title":["Organic Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.orglett.6c02715","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/orlef7\/article-pdf\/28\/33\/10463\/66483464\/acs.orglett.6c02715.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/orlef7\/article-pdf\/28\/33\/10463\/66483464\/acs.orglett.6c02715.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T16:11:04Z","timestamp":1787415064000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/orlef7\/article\/28\/33\/10463\/5251860\/Divergent-Synthesis-of-Ketones-and-Alcohols-via"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,11]]},"references-count":74,"journal-issue":{"issue":"33","published-online":{"date-parts":[[2026,8,11]]},"published-print":{"date-parts":[[2026,8,21]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.orglett.6c02715","relation":{},"ISSN":["1523-7060","1523-7052"],"issn-type":[{"value":"1523-7060","type":"print"},{"value":"1523-7052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,11]]}}}