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Based on this synergistic concept, the first 1,3-diazidation and 1,3-dichlorination of \u03b2,\u03b3-unsaturated ketones via 1,2-carbonyl migration have been developed, providing a versatile means to access various 1,3-diazides and 1,3-dichlorides. These reactions feature a broad substrate scope, high regioselectivity, and good functional group tolerance. The late-stage derivatization of complex molecules, large-scale synthesis, and facile postmodification of products demonstrate their significant application potential.<\/jats:p>","DOI":"10.1021\/acs.orglett.6c03008","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T01:01:36Z","timestamp":1786496496000},"page":"10589-10595","source":"Crossref","is-referenced-by-count":0,"title":["Radical 1,3-Difunctionalization\nof \u03b2,\u03b3-Unsaturated\nKetones via Synergistic LMCT and RLT Photocatalysis"],"prefix":"10.1021","volume":"28","author":[{"given":"Jingguo","family":"Liu","sequence":"first","affiliation":[{"name":"China Pharmaceutical University , , ,","place":["Nanjing, China, 210009"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Wang","sequence":"additional","affiliation":[{"name":"China Pharmaceutical University , , ,","place":["Nanjing, China, 210009"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Dong","sequence":"additional","affiliation":[{"name":"China Pharmaceutical University , , ,","place":["Nanjing, China, 210009"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7042-2397","authenticated-orcid":true,"given":"Bo","family":"Zhang","sequence":"additional","affiliation":[{"name":"China Pharmaceutical University , , ,","place":["Nanjing, China, 210009"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"2026082212103949800_cit1a","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1039\/C9CS00692C","article-title":"Intermolecular Radical Carboamination of Alkenes","volume":"49","author":"Jiang","year":"2020","journal-title":"Chem. 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