{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:56:39Z","timestamp":1791564999491,"version":"4.3.4"},"reference-count":35,"publisher":"American Chemical Society (ACS)","issue":"40","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100009103","name":"Education Department of Shaanxi Province","doi-asserted-by":"publisher","award":["25JP203"],"award-info":[{"award-number":["25JP203"]}],"id":[{"id":"10.13039\/501100009103","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22661055"],"award-info":[{"award-number":["22661055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Herein, we report a practical metal- and additive-free method for transfer hydrogenation of nitrones, employing a readily available PhSiH3 as the hydrogen donor. The findings demonstrated the effective conversion of a wide range of ketone- and aldehyde-derived nitrones into their corresponding hydroxylamine derivatives in good to excellent yields under mild conditions. The reaction is readily scalable and demonstrates broad functional group tolerance, accommodating bromo, chloro, fluoro, trifluoromethyl, thioether, thiophene, and furan substituents. Hence, the proposed operationally simple protocol provides a practical and sustainable strategy, facilitating the synthesis of structurally diverse hydroxylamine derivatives.<\/jats:p>","DOI":"10.1021\/acs.orglett.6c03328","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:01:47Z","timestamp":1790625707000},"page":"12570-12574","source":"Crossref","is-referenced-by-count":0,"title":["Transfer Hydrogenation\nof Nitrones to Hydroxylamine\nDerivatives with PhSiH3"],"prefix":"10.1021","volume":"28","author":[{"given":"Wanzhen","family":"Guo","sequence":"first","affiliation":[{"name":"Yan\u2019an University , , ,","place":["Yan\u2019an, P. R. China, 716000"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Liu","sequence":"additional","affiliation":[{"name":"Yan\u2019an University , , ,","place":["Yan\u2019an, P. R. China, 716000"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Lu","sequence":"additional","affiliation":[{"name":"Yan\u2019an University , , ,","place":["Yan\u2019an, P. R. China, 716000"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4773-2443","authenticated-orcid":true,"given":"Zhiqiang","family":"Ren","sequence":"additional","affiliation":[{"name":"Yan\u2019an University , , ,","place":["Yan\u2019an, P. R. China, 716000"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9577-3150","authenticated-orcid":true,"given":"Yuqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Yan\u2019an University , , ,","place":["Yan\u2019an, P. R. 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Rev."},{"key":"2026100910142011100_cit8b","doi-asserted-by":"publisher","first-page":"16628","DOI":"10.1002\/anie.202105093","article-title":"Rhodium-Catalyzed C\u2013H Activation-Based Construction of Axially\nand Centrally Chiral Indenes","volume":"60","author":"Wang","year":"2021","journal-title":"Angew. Chem.,\nInt. Ed."},{"key":"2026100910142011100_cit8c","unstructured":"(c)\n          \n            \n              Guo, W.; Liu, X.; Lu, X.; Ren, Z.; Zhang, Y.; Han, B.\n          Metal- and Additive-Free Transfer\nHydrogenation of Nitrones to Hydroxylamine Derivatives with PhSiH3.\n          ChemRxiv preprint, 2026. 10.26434\/chemrxiv.15006109\/v1."},{"key":"2026100910142011100_cit9","doi-asserted-by":"publisher","first-page":"8471","DOI":"10.1021\/acs.orglett.1c03176","article-title":"Enantioselective\nSynthesis of C\u03b1-Tetrasubstituted N-Hydroxyl-\u03b1-amino\nNitriles via Cyanation of Ketonitrones Using Me2(CH2Cl)SiCN","volume":"23","author":"Xu","year":"2021","journal-title":"Org. Lett."},{"key":"2026100910142011100_cit10","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1002\/adsc.201900718","article-title":"C\u2013H\nReactivity of the \u03b1-Position in Nitrones and Nitronates","volume":"362","author":"Sukhorukov","year":"2020","journal-title":"Adv. Synth. 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Commun."},{"key":"2026100910142011100_cit25","doi-asserted-by":"publisher","first-page":"2916","DOI":"10.1039\/D6OB00293E","article-title":"Catalyst- and additive-free\nreduction of carboxylic acids and amides\nusing ammonia borane as a hydrogen source","volume":"24","author":"Guo","year":"2026","journal-title":"Org.\nBiomol. Chem."},{"key":"2026100910142011100_cit26","doi-asserted-by":"publisher","first-page":"8338","DOI":"10.1021\/acs.orglett.5c02611","article-title":"Unexpected Reactivity of Nitrones:\nCatalytic Insertion of CS","volume":"27","author":"Lopez-Aguilar","year":"2025","journal-title":"Org. 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