{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:07:17Z","timestamp":1789751237374,"version":"4.0.1"},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"37","license":[{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100031918","name":"State Key Laboratory of Natural and Biomimetic Drugs","doi-asserted-by":"publisher","award":["KF2026009"],"award-info":[{"award-number":["KF2026009"]}],"id":[{"id":"10.13039\/100031918","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22371176"],"award-info":[{"award-number":["22371176"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Using the key intermediate previously established in our group\u2019s synthetic investigations of monoterpenoid indole alkaloids, concise and efficient total synthetic routes toward the 17-nor-excelsinidine and geissoschizoline were developed. The synthesis of 17-nor-excelsinidine relied on oxidative cyclization and intramolecular N-alkylation as the pivotal transformations. Following this strategy, a concise total synthesis of this alkaloid was accomplished. For geissoschizoline, we developed a biomimetic synthetic route featuring a cascade reaction sequence: Mn(OAc)3-mediated oxidative cyclization and skeletal reorganization. The target molecule was secured in a seven-step longest linear sequence, alongside a formal synthesis of dehydrogeissoschizoline.<\/jats:p>","DOI":"10.1021\/acs.orglett.6c03383","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:02:02Z","timestamp":1788775322000},"page":"11720-11725","source":"Crossref","is-referenced-by-count":0,"title":["Divergent Total\nSynthesis of 17-\n                    <i>nor<\/i>\n                    -Excelsinidine and Geissoschizoline"],"prefix":"10.1021","volume":"28","author":[{"given":"Zhi-Qi","family":"Cao","sequence":"first","affiliation":[{"name":"Shaanxi Normal University , , ,","place":["Xi\u2019an, China, 710119"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Kui","family":"Sun","sequence":"additional","affiliation":[{"name":"Shaanxi Normal University , , ,","place":["Xi\u2019an, China, 710119"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Shao","sequence":"additional","affiliation":[{"name":"Shaanxi Normal University , , ,","place":["Xi\u2019an, China, 710119"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0337-2558","authenticated-orcid":true,"given":"Yu-Ming","family":"Zhao","sequence":"additional","affiliation":[{"name":"Shaanxi Normal University , , ,","place":["Xi\u2019an, China, 710119"]},{"name":"Peking University , , ,","place":["Beijing, China, 100191"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"2026091809422551500_cit1a","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1039\/b512615k","article-title":"Chemistry and biology\nof monoterpene indole alkaloid biosynthesis","volume":"23","author":"O\u2019Connor","year":"2006","journal-title":"Nat. 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