{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:57:31Z","timestamp":1791565051228,"version":"4.3.4"},"reference-count":30,"publisher":"American Chemical Society (ACS)","issue":"40","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 115-2113-M-007-020"],"award-info":[{"award-number":["NSTC 115-2113-M-007-020"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Novel [3+2] annulations between imines and 1,3-diacyl gold carbenes have been developed to provide 2-acyl-3-aminopyrrole derivatives efficiently. Mechanistic studies suggest that the reaction is initiated by nucleophilic addition of the imine to the 1,3-diacyl gold carbene, generating a gold carbene\u2013imine intermediate that undergoes intramolecular carbocyclization involving the three-carbon 1,3-dicarbonyl unit and the C\u2550N bond to furnish the pyrrole framework. A competitive reaction in this gold catalysis is the Wolff reaction of the 1,3-diacyl gold carbenes when ynone substrates comprise bulky ketones. Density functional theory (DFT) calculations for the reaction of species 1a with 2a reveal that the [3+2] annulation pathway is energetically more favorable than the competing Wolff rearrangement.<\/jats:p>","DOI":"10.1021\/acs.orglett.6c03682","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:02:20Z","timestamp":1790650940000},"page":"12687-12692","source":"Crossref","is-referenced-by-count":0,"title":["Controlling\nthe Reactivity of 1,3-Diacyl-2-gold Carbenes:\n[3+2] Annulation with External Imines over Wolff Rearrangement"],"prefix":"10.1021","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0558-1628","authenticated-orcid":true,"given":"Vikas Ashokrao","family":"Sadaphal","sequence":"first","affiliation":[{"name":"National Tsing Hua University , , , ,","place":["Hsinchu, Taiwan, ROC, 300"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satish Bhausaheb","family":"Dawange","sequence":"additional","affiliation":[{"name":"National Tsing Hua University , , , ,","place":["Hsinchu, Taiwan, ROC, 300"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Qin","family":"Liao","sequence":"additional","affiliation":[{"name":"National Tsing Hua University , , , ,","place":["Hsinchu, Taiwan, ROC, 300"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Ru","family":"Wu","sequence":"additional","affiliation":[{"name":"National Tsing Hua University , , , ,","place":["Hsinchu, Taiwan, ROC, 300"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2011-8124","authenticated-orcid":true,"given":"Rai-Shung","family":"Liu","sequence":"additional","affiliation":[{"name":"National Tsing Hua University , , , ,","place":["Hsinchu, Taiwan, ROC, 300"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"2026100910135716200_cit1a","doi-asserted-by":"publisher","first-page":"7226","DOI":"10.1002\/anie.201100148","article-title":"Gold \u03b1-Oxo\nCarbenoids in Catalysis: Catalytic Oxygen-Atom Transfer to Alkynes","volume":"50","author":"Xiao","year":"2011","journal-title":"Angew. 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