{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:56:11Z","timestamp":1792158971873,"version":"4.4.0"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"41","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100010116","name":"Science and Technology Bureau of Nanchang Municipality","doi-asserted-by":"publisher","award":["2025YLWS0010"],"award-info":[{"award-number":["2025YLWS0010"]}],"id":[{"id":"10.13039\/501100010116","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22661030"],"award-info":[{"award-number":["22661030"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004479","name":"Natural Science Foundation of Jiangxi Province","doi-asserted-by":"publisher","award":["20252BAC240035"],"award-info":[{"award-number":["20252BAC240035"]}],"id":[{"id":"10.13039\/501100004479","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013798","name":"Jiangxi Science and Technology Normal University","doi-asserted-by":"publisher","award":["2025BSQD053"],"award-info":[{"award-number":["2025BSQD053"]}],"id":[{"id":"10.13039\/501100013798","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Nanchang Health Commission","award":["2025YLWS0010"],"award-info":[{"award-number":["2025YLWS0010"]}]},{"name":"Third Affiliated Hospital, Nanchang University","award":["BSQD2025072101"],"award-info":[{"award-number":["BSQD2025072101"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Alkoxy radical-mediated hydroetherification offers an atom-economical approach for C\u2013O bond construction. However, the difunctionalization of alkenes driven by alkoxy radicals remains elusive due to the inherent challenges associated with the generation and controlled reactivity of these reactive oxygen-centered radicals. Here we report a homogeneous molecular electrophotochemical LMCT catalysis strategy that enables the difunctionalization of enol derivatives, achieving efficient alkenyletherification to access a diverse array of functionalized ethers. This method features mild conditions, broad substrate scope encompassing both electron-rich and electron-deficient alkenes, and effective suppression of direct alkene oxidation side reactions. Detailed mechanistic studies reveal that a visible-light-induced ligand-to-metal charge transfer (LMCT) process selectively activates the alcohol hydroxyl group, generating a highly electrophilic alkoxy radical in situ to initiate the anti-Markovnikov intramolecular addition to the alkene. Subsequent electrochemical oxidation precisely dictates the fate of the resulting carbon-centered radical, enabling the introduction of an alkenyl group, respectively, to ultimately yield the target products.<\/jats:p>","DOI":"10.1021\/acs.orglett.6c03725","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:01:34Z","timestamp":1791345694000},"page":"12941-12946","source":"Crossref","is-referenced-by-count":0,"title":["Alkoxy Radical-Mediated\nAlkene Difunctionalization\nvia Electrophotochemical LMCT Catalysis for the Synthesis of Functionalized\nEthers"],"prefix":"10.1021","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7447-5821","authenticated-orcid":true,"given":"Caolin","family":"Wang","sequence":"first","affiliation":[{"name":"Nanchang University , , , ,","place":["Nanchang, Jiangxi, China, 330008"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxin","family":"Huang","sequence":"additional","affiliation":[{"name":"Nanchang University , , , ,","place":["Nanchang, Jiangxi, China, 330008"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5034-4467","authenticated-orcid":true,"given":"Jianye","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jiangxi Science & Technology Normal University , , ,","place":["Nanchang, P. 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China, 330013"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[{"name":"Nanchang University , , , ,","place":["Nanchang, Jiangxi, China, 330008"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Cheng","sequence":"additional","affiliation":[{"name":"Nanchang University , , , ,","place":["Nanchang, Jiangxi, China, 330008"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaorong","family":"Yang","sequence":"additional","affiliation":[{"name":"Nanchang University , , , ,","place":["Nanchang, Jiangxi, China, 330006"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"issue":"9","key":"2026101608465005500_cit1","doi-asserted-by":"publisher","first-page":"2127","DOI":"10.1093\/jn\/130.9.2127","article-title":"Phytosterols as Anticancer Dietary Components: Evidence\nand Mechanism of Action","volume":"130","author":"Awad","year":"2000","journal-title":"J. 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