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Key features of the synthesis include the stereoselective construction of \u03b1-1,3-linked galacto-disaccharide motif, the sequential assembly of the \u03b1-1,2-, \u03b1-1,3-, and \u03b1-1,4-alternating rhamno-oligosaccharide fragments, and the regioselective xylosylation at predefined positions. All target molecules were functionalized with an aminopropyl linker to facilitate their conjugation to carrier biomolecules for subsequent immunological studies.<\/jats:p>","DOI":"10.1021\/acs.orglett.6c03890","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:01:54Z","timestamp":1790247714000},"page":"12525-12530","source":"Crossref","is-referenced-by-count":0,"title":["Convergent Synthesis\nof Conjugation-Ready Oligosaccharide\nHaptens Corresponding to Undecasaccharide Repeating Unit of\n                    <i>Burkholderia pseudomallei<\/i>\n                    Lipopolysaccharide Type\nB O-Antigen"],"prefix":"10.1021","volume":"28","author":[{"given":"Longfei","family":"Ren","sequence":"first","affiliation":[{"name":"Shandong University , , 72 Binhai Road , ,","place":["Qingdao, China, 266237"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shandong University , , 72 Binhai Road , ,","place":["Qingdao, China, 266237"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaijie","family":"Jia","sequence":"additional","affiliation":[{"name":"Shandong University , , 72 Binhai Road , ,","place":["Qingdao, China, 266237"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9887-6665","authenticated-orcid":true,"given":"Xiaoyu","family":"Xu","sequence":"additional","affiliation":[{"name":"Shandong University , , 72 Binhai Road , ,","place":["Qingdao, China, 266237"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Liu","sequence":"additional","affiliation":[{"name":"Shandong University , , 72 Binhai Road , ,","place":["Qingdao, China, 266237"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0969-7487","authenticated-orcid":true,"given":"Guofeng","family":"Gu","sequence":"additional","affiliation":[{"name":"Shandong University , , 72 Binhai Road , ,","place":["Qingdao, China, 266237"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"issue":"3","key":"2026100208375365800_cit1","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1038\/s41579-023-00972-5","article-title":"Burkholderia Pseudomallei and Melioidosis","volume":"22","author":"Meumann","year":"2024","journal-title":"Nat. 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Microbiol."},{"issue":"2","key":"2026100208375365800_cit8","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0001-706X(00)00139-X","article-title":"Melioidosis\nResearch in China","volume":"77","author":"Yang","year":"2000","journal-title":"Acta Trop"},{"issue":"11","key":"2026100208375365800_cit9","doi-asserted-by":"publisher","first-page":"000659","DOI":"10.1099\/mgen.0.000659","article-title":"Genetic Diversity and\nTransmission Patterns of Burkholderia Pseudomallei on Hainan Island, China, Revealed by a Population Genomics Analysis","volume":"7","author":"Zheng","year":"2021","journal-title":"Microb. 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