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The nucleoside 3\u2032-O-phosphoramidites were successfully incorporated into oligonucleotides on a solid support, whereas the nucleoside triphosphates served as good substrates for polymerase synthesis of modified DNA, which underwent fast and efficient copper-catalyzed alkyne\u2013azide 1,3-dipolar cycloaddition (CuAAC) reactions.<\/jats:p>","DOI":"10.1021\/acs.orglett.8b01533","type":"journal-article","created":{"date-parts":[[2018,6,13]],"date-time":"2018-06-13T12:18:17Z","timestamp":1528892297000},"page":"3962-3965","source":"Crossref","is-referenced-by-count":33,"title":["Flexible Alkyne-Linked Thymidine Phosphoramidites\nand Triphosphates for Chemical or Polymerase Synthesis and Fast Postsynthetic\nDNA Functionalization through Copper-Catalyzed Alkyne\u2013Azide\n1,3-Dipolar Cycloaddition"],"prefix":"10.1021","volume":"20","author":[{"given":"Alessandro","family":"Panattoni","sequence":"first","affiliation":[{"name":"Czech Academy of Sciences , , Flemingovo namesti 2 , ,","place":["Prague 6, Czech Republic, CZ-16610"]},{"name":"Charles University in Prague , , Hlavova 8 , ,","place":["Prague 2, Czech Republic, CZ-12843"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radek","family":"Pohl","sequence":"additional","affiliation":[{"name":"Czech Academy of Sciences , , Flemingovo namesti 2 , ,","place":["Prague 6, Czech Republic, CZ-16610"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1113-2047","authenticated-orcid":true,"given":"Michal","family":"Hocek","sequence":"additional","affiliation":[{"name":"Czech Academy of Sciences , , Flemingovo namesti 2 , ,","place":["Prague 6, Czech Republic, CZ-16610"]},{"name":"Charles University in Prague , , Hlavova 8 , ,","place":["Prague 2, Czech Republic, CZ-12843"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2018,6,13]]},"reference":[{"key":"2026090121573870200_cit1a","doi-asserted-by":"publisher","first-page":"2054","DOI":"10.1039\/b911431a","volume":"39","author":"Singh","year":"2010","journal-title":"Chem. 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