{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:50:49Z","timestamp":1791082249738,"version":"4.1.0"},"reference-count":70,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T00:00:00Z","timestamp":1719878400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T00:00:00Z","timestamp":1719878400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T00:00:00Z","timestamp":1719878400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100005303","name":"Boston College","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005303","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006770","name":"American Chemical Society Petroleum Research Fund","doi-asserted-by":"publisher","award":["66299-DNI10"],"award-info":[{"award-number":["66299-DNI10"]}],"id":[{"id":"10.13039\/100006770","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2211334"],"award-info":[{"award-number":["2211334"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Bio Mater."],"published-print":{"date-parts":[[2024,7,15]]},"DOI":"10.1021\/acsabm.4c00484","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T12:06:06Z","timestamp":1719921966000},"page":"4622-4632","source":"Crossref","is-referenced-by-count":10,"title":["Graphene Multiplexed Sensor for Point-of-Need Viral Wastewater-Based Epidemiology"],"prefix":"10.1021","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7197-9381","authenticated-orcid":true,"given":"Michael","family":"Geiwitz","sequence":"first","affiliation":[{"name":"Department of Physics, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owen Rivers","family":"Page","sequence":"additional","affiliation":[{"name":"Department of Biology, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tio","family":"Marello","sequence":"additional","affiliation":[{"name":"Department of Physics, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4355-809X","authenticated-orcid":true,"given":"Marina E.","family":"Nichols","sequence":"additional","affiliation":[{"name":"Department of Physics, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narendra","family":"Kumar","sequence":"additional","affiliation":[{"name":"GRIP Molecular Technologies, Inc., 1000 Westgate Drive, Saint Paul, Minnesota 55114, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Hummel","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Life Science, United States Military Academy, West Point, New York 10996, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vsevolod","family":"Belosevich","sequence":"additional","affiliation":[{"name":"Department of Physics, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5103-6973","authenticated-orcid":true,"given":"Qiong","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Physics, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"van Opijnen","sequence":"additional","affiliation":[{"name":"Department of Biology, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Batten","sequence":"additional","affiliation":[{"name":"GRIP Molecular Technologies, Inc., 1000 Westgate Drive, Saint Paul, Minnesota 55114, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle M.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of Biology, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7541-0245","authenticated-orcid":true,"given":"Kenneth S.","family":"Burch","sequence":"additional","affiliation":[{"name":"Department of Physics, Boston College, Chestnut Hill, Massachusetts 02467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,7,2]]},"reference":[{"key":"ref1\/cit1","unstructured":"World Health Organization. Top 10 causes of death. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/the-top-10-causes-of-death (accessed Jan 10, 2024)."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1908380"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06323-9"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1371\/JOURNAL.PMED.1003550"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.138875"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1328452"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-020-0684-z"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1128\/msystems.00793-21"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.140719"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.140680"},{"key":"ref11\/cit11","unstructured":"CDC. Update on RSV and New Vaccine Recommendation\n| CDC. https:\/\/www.cdc.gov\/respiratory-viruses\/whats-new\/rsv-update-2023-09-22.html (accessed Nov 06, 2023)."},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-023-02960-4"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.2166\/wh.2023.057"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.coesh.2019.05.007"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-021-00535-6"},{"key":"ref16\/cit16","unstructured":"Biobot. FAQ\u2500Variant Sequencing\u2500Biobot\nAnalytics. https:\/\/support.biobot.io\/hc\/en-us\/articles\/14910772709527-FAQ-Variant-Sequencing (accessed Nov 06, 2023)."},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1042\/BIO20200034"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","DOI":"10.1002\/9781118671276","volume-title":"Handbook of LC-MS Bioanalysis: Best Practices, Experimental Protocols, and and Regulations","author":"Li W.","year":"2013"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11092356"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2023.463896"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0284370"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1101\/2020.03.28.20043059"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2196-x"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2022.113307"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/mds3.10121"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2021.113605"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c07094"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1039\/D2NA00416J"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1103\/RevModPhys.81.109"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c02823"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2013.05.022"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3390\/s21041335"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/nl201332c"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b04110"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2020.112123"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1515\/bnm-2016-0012"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1039\/C3AN02117C"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/29.4.943"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2022.339511"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2016.199"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2013.11.041"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1038\/srep42794"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2022.07.012"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-023-04760-1"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2017.07.048"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1063\/5.0006462"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.desal.2010.05.037"},{"key":"ref48\/cit48","unstructured":"Stern, E. Label-Free Sensing with Semiconducting Nanowires, 2007. http:\/\/entity.eng.yale.edu\/reedlab\/publications\/Stern_PhDthesis_FINAL.pdf (accessed Dec 28, 2023)."},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.7b09301"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s42005-021-00518-2"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-8206.2008.00633.x"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2014.05.018"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2022.118985"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c04349"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2665-2"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.05.004"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-6535(98)00090-3"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.0c00664"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.0c00412"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.2c00280"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.3390\/v14050872"},{"key":"ref62\/cit62","unstructured":"Biobot. FAQ\u2500Technical Questions: Results\u2500Biobot\nAnalytics. https:\/\/support.biobot.io\/hc\/en-us\/articles\/360052012934-FAQ-Technical-Questions-Results (accessed Nov 06, 2023)."},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-019-10077-w"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.141364"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30113-4"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1038\/s44222-022-00007-3"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.00140-22"},{"key":"ref68\/cit68","unstructured":"Biobot Launches COVID-19 Detection, Modeling\nvia Wastewater Analysis\n| BioSpace. https:\/\/www.biospace.com\/article\/releases\/biobot-launches-covid-19-detection-modeling-via-wastewater-analysis\/ (accessed June 05, 2024)."},{"key":"ref69\/cit69","volume-title":"Guide to Achieving Reliable Quantitative LC-MS Measurements","author":"Sargent M.","year":"2013","edition":"1"},{"key":"ref70\/cit70","unstructured":"Rates\n| Harvard Center for\nMass Spectrometry. https:\/\/massspec.fas.harvard.edu\/pages\/rates (accessed June 05, 2024)"}],"container-title":["ACS Applied Bio Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.4c00484","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.4c00484","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T04:52:32Z","timestamp":1721019152000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsabm.4c00484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,2]]},"references-count":70,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7,15]]}},"alternative-id":["10.1021\/acsabm.4c00484"],"URL":"https:\/\/doi.org\/10.1021\/acsabm.4c00484","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.03.18.24304492","asserted-by":"object"}]},"ISSN":["2576-6422","2576-6422"],"issn-type":[{"value":"2576-6422","type":"print"},{"value":"2576-6422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,2]]}}}