{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:18:02Z","timestamp":1778822282975,"version":"3.51.4"},"reference-count":110,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100008790","name":"National Institute of Technology Rourkela","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008790","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["SRG\/2021\/000859"],"award-info":[{"award-number":["SRG\/2021\/000859"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Bio Mater."],"published-print":{"date-parts":[[2024,12,16]]},"DOI":"10.1021\/acsabm.4c00813","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T16:04:44Z","timestamp":1732118684000},"page":"8107-8125","source":"Crossref","is-referenced-by-count":3,"title":["A Review on Microengineering of Epithelial Barriers for Biomedical and Pharmaceutical Research"],"prefix":"10.1021","volume":"7","author":[{"given":"Ruchira","family":"Chakraborty","sequence":"first","affiliation":[{"name":"Biodesign and Medical Devices Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela 769008, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pragyan","family":"Ray","sequence":"additional","affiliation":[{"name":"Biodesign and Medical Devices Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela 769008, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swagatika","family":"Barik","sequence":"additional","affiliation":[{"name":"Biodesign and Medical Devices Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela 769008, Odisha, India"},{"name":"Opto-Biomedical Microsystem Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Sector-1, Rourkela 769008, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oindrila","family":"Banik","sequence":"additional","affiliation":[{"name":"Biodesign and Medical Devices Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela 769008, Odisha, India"},{"name":"Opto-Biomedical Microsystem Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Sector-1, Rourkela 769008, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8819-6682","authenticated-orcid":true,"given":"Chinmaya","family":"Mahapatra","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, National Institute of Technology, Raipur-492010 Chhattisgarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Earu","family":"Banoth","sequence":"additional","affiliation":[{"name":"Opto-Biomedical Microsystem Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Sector-1, Rourkela 769008, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0854-3889","authenticated-orcid":true,"given":"Prasoon","family":"Kumar","sequence":"additional","affiliation":[{"name":"Biodesign and Medical Devices Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela 769008, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2024,11,20]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.2741\/3180"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.11.023"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202200154R"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izaa354"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izac217"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(06)00040-6"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3390\/cells11020307"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2015111285"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00538-7"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering10050517"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X18788769"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1126\/science.1188302"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-34390-y"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1177\/1535370217710638"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4835(03)00033-2"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1038518"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2020.101372"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0197101"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-1693-2_4"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/c2lc40074j"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-019-0397-0"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202001600RR"},{"key":"ref115\/cit115","doi-asserted-by":"publisher","DOI":"10.1039\/C6LC00229C"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1039\/C6LC00259E"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c21573"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3390\/bios11090314"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1039\/C5LC00530B"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1039\/D1RA03410C"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.0c01741"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1186\/1478-811X-9-29"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2018.06.068"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1111\/jopr.13017"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.09.020"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.2c00202"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2007.10.004"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1089\/biores.2015.0037"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.5772\/21634"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines9060631"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1007\/164_2020_429"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcb.2004.10.005"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9050417"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.797491"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2012.07.007"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2012.0603"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2009.0277"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/jps.24315"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics12100988"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2017.08.002"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116502"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1023\/B:PHAM.0000003380.44755.5a"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2019.02.035"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.200709849"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2015.07.028"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2016.08.041"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2017.12.025"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-1108-9"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.3311\/PPch.15601"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1186\/s12987-022-00379-z"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1007\/s13577-024-01115-5"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c07195"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.3390\/cells12162067"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-022-03026-3"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2013.02.005"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1601306113"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1021\/mp5001422"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2017.0276"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2015.06.023"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1039\/D1NA00280E"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1039\/C4AN01276C"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-27300-w"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-006-0256-z"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1002\/cpns.25"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.3390\/mps5010017"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1039\/D1LC01046H"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1007\/s10544-017-0251-7"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-012110-142150"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.8b03842"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21030742"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13378"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13374"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.2c00931"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1021\/la504269t"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.9b00390"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0178966"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-46497-x"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.12147"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2017.00421"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201908-1513OC"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00740-18"},{"key":"ref95\/cit95","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000002348"},{"key":"ref96\/cit96","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics11030129"},{"key":"ref97\/cit97","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2014.08.003"},{"key":"ref98\/cit98","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2018.01.042"},{"key":"ref99\/cit99","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.18-23944"},{"key":"ref100\/cit100","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2021.120211"},{"key":"ref101\/cit101","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.0c00390"},{"key":"ref102\/cit102","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2017.05.038"},{"key":"ref103\/cit103","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2010.01910.x"},{"key":"ref104\/cit104","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00074.2017"},{"key":"ref105\/cit105","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.6.9908135"},{"key":"ref106\/cit106","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2006.08.015"},{"key":"ref107\/cit107","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.1999.5786"},{"key":"ref108\/cit108","doi-asserted-by":"publisher","DOI":"10.1002\/gch2.201800112"},{"key":"ref109\/cit109","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2020.105775"},{"key":"ref116\/cit116","doi-asserted-by":"publisher","DOI":"10.1177\/4.6.531"},{"key":"ref110\/cit110","doi-asserted-by":"publisher","DOI":"10.1007\/s12015-021-10205-y"},{"key":"ref111\/cit111","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202002590RRR"},{"key":"ref112\/cit112","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2023.100910"},{"key":"ref113\/cit113","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-809880-6.00044-8"},{"key":"ref114\/cit114","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2019.00474"}],"container-title":["ACS Applied Bio Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.4c00813","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.4c00813","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T09:10:51Z","timestamp":1734340251000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsabm.4c00813"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,20]]},"references-count":110,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12,16]]}},"alternative-id":["10.1021\/acsabm.4c00813"],"URL":"https:\/\/doi.org\/10.1021\/acsabm.4c00813","relation":{},"ISSN":["2576-6422","2576-6422"],"issn-type":[{"value":"2576-6422","type":"print"},{"value":"2576-6422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,20]]}}}