{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:31:40Z","timestamp":1790829100240,"version":"4.1.0"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012359","name":"Promotion and Mutual Aid Corporation for Private Schools of Japan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012359","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Chuo Univeristy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Bio Mater."],"published-print":{"date-parts":[[2025,3,17]]},"DOI":"10.1021\/acsabm.4c01901","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T07:25:37Z","timestamp":1739431537000},"page":"2397-2407","source":"Crossref","is-referenced-by-count":8,"title":["Nanoparticle O\n                    <sub>2<\/sub>\n                    Carrier Composed of a Polymerized Stroma-Free Hemoglobin Core and Serum Albumin Shell as a Red Blood Cell Alternative in Hemorrhagic Shock Therapy"],"prefix":"10.1021","volume":"8","author":[{"given":"Natsumi","family":"Kohyama","sequence":"first","affiliation":[{"name":"Department of Applied Chemistry, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koki","family":"Takamine","sequence":"additional","affiliation":[{"name":"Department of Applied Chemistry, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wataru","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Applied Chemistry, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4118-5828","authenticated-orcid":true,"given":"Taiga","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Applied Chemistry, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoshi","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Saitama 350-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsutomo","family":"Kohno","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Saitama 350-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6720-9970","authenticated-orcid":true,"given":"Ryota","family":"Tochinai","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathophysiology and Animal Health, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7622-3433","authenticated-orcid":true,"given":"Teruyuki","family":"Komatsu","sequence":"additional","affiliation":[{"name":"Department of Applied Chemistry, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13780"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.19.233361"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3343\/alm.2022.42.3.306"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.8b00093"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000001009"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.118.254664"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000003957"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.partic.2021.08.010"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/s40005-022-00590-y"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/0955-3886(95)93436-A"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/ac050064y"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2009.04.008"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/nn402073n"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13726"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.3c00611"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2003.00341.x"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/bc0200733"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/bc900170e"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12934"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.1c00061"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.3c00392"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/bm400204y"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.8b03474"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.35040"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.1c00424"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15427"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2022007977"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.19.jrv80007"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2008.00697.x"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2004.6.967"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3109\/10731199.2011.581052"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.2c00813"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/ja300893t"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/bi00707a027"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/bip.20044"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/bi300347x"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2016.05.005"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.15.8607"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/bc0340619"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1039\/c3dt51418h"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/ja050339r"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c14822"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110541"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2023.148592"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000412"}],"container-title":["ACS Applied Bio Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.4c01901","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.4c01901","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T04:11:39Z","timestamp":1742184699000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsabm.4c01901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,13]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3,17]]}},"alternative-id":["10.1021\/acsabm.4c01901"],"URL":"https:\/\/doi.org\/10.1021\/acsabm.4c01901","relation":{},"ISSN":["2576-6422","2576-6422"],"issn-type":[{"value":"2576-6422","type":"print"},{"value":"2576-6422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,13]]}}}