{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:44:54Z","timestamp":1790790294937,"version":"4.1.0"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFA1200104"],"award-info":[{"award-number":["2021YFA1200104"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22304171"],"award-info":[{"award-number":["22304171"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273314"],"award-info":[{"award-number":["82273314"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDB36000000"],"award-info":[{"award-number":["XDB36000000"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Bio Mater."],"published-print":{"date-parts":[[2025,8,18]]},"DOI":"10.1021\/acsabm.5c00882","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T05:08:03Z","timestamp":1754284083000},"page":"7113-7125","source":"Crossref","is-referenced-by-count":1,"title":["Tumor Microenvironment-Responsive Nanocluster for Time-Resolved Hyperthermic Intraperitoneal Chemo\/Thermal-Therapy against Colorectal Peritoneal Metastasis"],"prefix":"10.1021","volume":"8","author":[{"given":"Qiping","family":"Wu","sequence":"first","affiliation":[{"name":"Institute of Biomedical Engineering, College of Life Sciences","place":["Qingdao, China"]},{"name":"Qingdao University","place":["Qingdao, China"]},{"name":"Center for Bioanalytical Chemistry, Hefei National Laboratory of Physical Science at Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanzhou","family":"Wang","sequence":"additional","affiliation":[{"name":"Departments of Colorectal Surgery","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University Cancer Center","place":["Guangzhou, China"]},{"name":"State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University Cancer Center","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiwen","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Bioanalytical Chemistry, Hefei National Laboratory of Physical Science at Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]},{"name":"School of Biomedical Sciences","place":["Changsha, China"]},{"name":"Hunan University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zichao","family":"Wang","sequence":"additional","affiliation":[{"name":"Departments of Colorectal Surgery","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University Cancer Center","place":["Guangzhou, China"]},{"name":"State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University Cancer Center","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9828-4560","authenticated-orcid":true,"given":"Yujie","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs, College of Life Science and Technology","place":["Guangzhou, China"]},{"name":"Jinan University","place":["Guangzhou, China"]},{"name":"Center for Bioanalytical Chemistry, Hefei National Laboratory of Physical Science at Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1549-9820","authenticated-orcid":true,"given":"Yuanhong","family":"Xu","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, College of Life Sciences","place":["Qingdao, China"]},{"name":"Qingdao University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Shen","sequence":"additional","affiliation":[{"name":"Departments of Colorectal Surgery","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University Cancer Center","place":["Guangzhou, China"]},{"name":"State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University Cancer Center","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,8,4]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21763"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviscsurg.2020.12.012"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2004.01.029"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(04)01425-1"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1515\/pp-2017-0003"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1456"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2024.102183"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15235641"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol31070269"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1159\/000528609"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2021.0580"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1200\/jco.22.01690"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2003.04.187"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1136\/egastro-2023-100016"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.2165\/11598890-000000000-00000"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.18.01688"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2020.6363"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2009.23.9285"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30599-4"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2022.0143"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-023-01790-2"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1159\/000538373"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2020.503252"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v11.i4.190"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.bulcan.2023.01.011"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.4103\/ijpvm.IJPVM_40_17"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b03375"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.2147\/dddt.s150201"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2784-6"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2018.8508"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2022.02.022"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkae001"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b04763"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201813702"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201910815"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1186\/s40104-019-0408-8"}],"container-title":["ACS Applied Bio Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.5c00882","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.5c00882","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T08:11:49Z","timestamp":1755504709000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsabm.5c00882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,4]]},"references-count":36,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,18]]}},"alternative-id":["10.1021\/acsabm.5c00882"],"URL":"https:\/\/doi.org\/10.1021\/acsabm.5c00882","relation":{},"ISSN":["2576-6422","2576-6422"],"issn-type":[{"value":"2576-6422","type":"print"},{"value":"2576-6422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,4]]}}}