{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T08:50:53Z","timestamp":1782204653717,"version":"3.54.5"},"reference-count":58,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["No. 21705084"],"award-info":[{"award-number":["No. 21705084"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shandong Province Graduate High Quality Professional Degree Teaching Case Library Project","award":["No. SDYAL2025093"],"award-info":[{"award-number":["No. SDYAL2025093"]}]},{"name":"Undergraduate Teaching Reform Research Project of Qilu University of Technology","award":["No. 2025zd0"],"award-info":[{"award-number":["No. 2025zd0"]}]},{"name":"Training Program of Innovation and Entrepreneurship for Undergraduates of Shandong Province","award":["No. S202510431026X"],"award-info":[{"award-number":["No. S202510431026X"]}]},{"name":"Shandong Province Science and Technology based Small and Medium sized Enterprises Innovation Capability Enhancement Project","award":["No. 2024TSGC1000"],"award-info":[{"award-number":["No. 2024TSGC1000"]}]},{"name":"Special Funds for Taishan Scholars Project","award":["No. ts201712060"],"award-info":[{"award-number":["No. ts201712060"]}]},{"name":"Major Innovation Project of Qilu University of Technology (Shandong Academy of Sciences) Technology Industry Integration Pilot Project","award":["No. 2025ZDZX15"],"award-info":[{"award-number":["No. 2025ZDZX15"]}]},{"name":"Key Supporting Regions Introduce Urgently Needed Talent Projects of Shandong Province","award":["No. 2309-371724-89-01-660290"],"award-info":[{"award-number":["No. 2309-371724-89-01-660290"]}]},{"name":"Undergraduate Teaching Reform Research Project of Shandong Province","award":["No. M2023021"],"award-info":[{"award-number":["No. M2023021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Bio Mater."],"published-print":{"date-parts":[[2026,4,20]]},"DOI":"10.1021\/acsabm.6c00225","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T13:00:36Z","timestamp":1775566836000},"page":"3946-3956","source":"Crossref","is-referenced-by-count":0,"title":["Intelligent \u03b1-Cyclodextrin-Based Nanomachines Co-loading Lenalidomide and Au@TPE for NIR-I-Light Programmed Combinatorial Breast Cancer Therapy"],"prefix":"10.1021","volume":"9","author":[{"given":"Ying","family":"Tian","sequence":"first","affiliation":[{"name":"School of Food Science and Engineering, State Key Laboratory of Biobased Material and Green Papermaking, School of Materials Science and Engineering","place":["Jinan, China"]},{"name":"Qilu University of Technology, Shandong Academy of Sciences","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxuan","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Food Science and Engineering, State Key Laboratory of Biobased Material and Green Papermaking, School of Materials Science and Engineering","place":["Jinan, China"]},{"name":"Qilu University of Technology, Shandong Academy of Sciences","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Che","sequence":"additional","affiliation":[{"name":"School of Food Science and Engineering, State Key Laboratory of Biobased Material and Green Papermaking, School of Materials Science and Engineering","place":["Jinan, China"]},{"name":"Qilu University of Technology, Shandong Academy of Sciences","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Food Science and Engineering, State Key Laboratory of Biobased Material and Green Papermaking, School of Materials Science and Engineering","place":["Jinan, China"]},{"name":"Qilu University of Technology, Shandong Academy of Sciences","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Cui","sequence":"additional","affiliation":[{"name":"School of Food Science and Engineering, State Key Laboratory of Biobased Material and Green Papermaking, School of Materials Science and Engineering","place":["Jinan, China"]},{"name":"Qilu University of Technology, Shandong Academy of Sciences","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9575-8997","authenticated-orcid":true,"given":"Yishan","family":"Fang","sequence":"additional","affiliation":[{"name":"School of Food Science and Engineering, State Key Laboratory of Biobased Material and Green Papermaking, School of Materials Science and Engineering","place":["Jinan, China"]},{"name":"Qilu University of Technology, Shandong Academy of Sciences","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.111168"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.06.015"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.101073"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.08.055"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1007\/s10853-018-2668-7"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.3c00159"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-42740-2"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c10453"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.07.022"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.09.024"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2025.118155"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2025.11.010"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202500513"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3390\/polym17091258"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2025.123793"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c09978"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2024.123202"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.2174\/1568026616666161222101104"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.14344)"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/ar000174l"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/s10847-006-9052-y"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/nano8120985"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1039\/C7SC05414A"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201800581"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2021.101118"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70380-2"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2012.119"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2024014655"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2025.106923"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-021-00315-x"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2018.8120"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-020-0209-9"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-023-01721-y"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2020.11.022"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2025.167452"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/D2NR03408E"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfa.2025.138429"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2018.12.004"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2021.130775"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08722-z"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202007525"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC02911D"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37150-3"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.119551"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/srep25613"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c00891"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-011-0670-5"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-019-0403-2"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/nature14610"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2010.11.002"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2022.108692"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/1769374"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/51.5.1409"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.000976"},{"issue":"2","key":"ref55\/cit55","first-page":"584","volume":"45","author":"Osborne C. K.","year":"1985","journal-title":"Cancer Res."},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2010.11.002"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-18-0044"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-16-0114"}],"container-title":["ACS Applied Bio Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.6c00225","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.6c00225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T08:26:09Z","timestamp":1782203169000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsabm.6c00225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,7]]},"references-count":58,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,4,20]]}},"alternative-id":["10.1021\/acsabm.6c00225"],"URL":"https:\/\/doi.org\/10.1021\/acsabm.6c00225","relation":{},"ISSN":["2576-6422","2576-6422"],"issn-type":[{"value":"2576-6422","type":"print"},{"value":"2576-6422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,7]]}}}