{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T10:46:23Z","timestamp":1782384383830,"version":"3.54.5"},"reference-count":56,"publisher":"American Chemical Society (ACS)","issue":"9","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100015377","name":"Shanghai Key Laboratory of Molecular Imaging","doi-asserted-by":"publisher","award":["18DZ2260400"],"award-info":[{"award-number":["18DZ2260400"]}],"id":[{"id":"10.13039\/501100015377","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32301160"],"award-info":[{"award-number":["32301160"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272057"],"award-info":[{"award-number":["82272057"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82402356"],"award-info":[{"award-number":["82402356"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Bio Mater."],"published-print":{"date-parts":[[2026,5,4]]},"DOI":"10.1021\/acsabm.6c00454","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T10:01:31Z","timestamp":1776160891000},"page":"4297-4313","source":"Crossref","is-referenced-by-count":0,"title":["Relaxation Suppressed Exchange Tuning MRI Integrated with Manganese-Based Nanozyme Probes for Ferroptosis Induction and GPX4 Monitoring"],"prefix":"10.1021","volume":"9","author":[{"given":"Xinyi","family":"Ding","sequence":"first","affiliation":[{"name":"Shanghai Key Laboratory of Molecular Imaging","place":["Shanghai, China"]},{"name":"Shanghai University of Medicine and Health Sciences","place":["Shanghai, China"]},{"name":"Department of Radiology","place":["Shanghai, China"]},{"name":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Radiology","place":["Shanghai, China"]},{"name":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyan","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, College of Engineering","place":["Shantou, China"]},{"name":"Shantou University","place":["Shantou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiali","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Radiology","place":["Shanghai, China"]},{"name":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyi","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Health Science and Engineering","place":["Shanghai, China"]},{"name":"University of Shanghai for Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhu","family":"Mei","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of Pancreatic Diseases, Department of Gastroenterology","place":["Shanghai, China"]},{"name":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiance","family":"Zhao","sequence":"additional","affiliation":[{"name":"Philips Healthcare","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, College of Engineering","place":["Shantou, China"]},{"name":"Shantou University","place":["Shantou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology","place":["Shanghai, China"]},{"name":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5477-1287","authenticated-orcid":true,"given":"Zhongling","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology","place":["Shanghai, China"]},{"name":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,4,14]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2022.09.021"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-01969-z"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2024.03.004"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3390\/biology10030184"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.15212\/AMM-2024-0083"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21763"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2022-071674"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122935"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202500337"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-025-01873-9"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116512"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2015.158"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1007\/s11426-022-1250-5"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2024.05.006"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1039\/d4sc07953a"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.4c00244"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01366-y"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/cbmi.3c00024"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-020-0678-5"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2022.101524"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/s40843-024-3103-x"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202507526"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121502"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202207174"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202510010"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1039\/c7cs00657h"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.5b00038"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2024.08.036"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbaf042"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02502-8"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202400474"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202312316"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202206074"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-020-2839-0"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c02309"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.6c00700"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22761"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1006\/jmre.1999.1956"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10651"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.07.025"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26232"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-019-0503-4"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S454486"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.5b04517"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-025-01672-3"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-42286-3"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21928"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/ja406738y"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.3054"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121620"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-024-01286-4"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202313485"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122633"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2025.165765"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202519194"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-53906-x"}],"container-title":["ACS Applied Bio Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.6c00454","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.6c00454","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T09:49:18Z","timestamp":1782380958000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsabm.6c00454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,14]]},"references-count":56,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,5,4]]}},"alternative-id":["10.1021\/acsabm.6c00454"],"URL":"https:\/\/doi.org\/10.1021\/acsabm.6c00454","relation":{},"ISSN":["2576-6422","2576-6422"],"issn-type":[{"value":"2576-6422","type":"print"},{"value":"2576-6422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,14]]}}}