{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:44:34Z","timestamp":1791333874622,"version":"4.3.1"},"reference-count":67,"publisher":"American Chemical Society (ACS)","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China (973 Program)","doi-asserted-by":"crossref","award":["2021YFC2102300"],"award-info":[{"award-number":["2021YFC2102300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["22375144"],"award-info":[{"award-number":["22375144"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["32071384"],"award-info":[{"award-number":["32071384"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Bio Mater."],"DOI":"10.1021\/acsabm.6c00539","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T17:45:21Z","timestamp":1781027121000},"source":"Crossref","is-referenced-by-count":1,"title":["Oral Cobalt Coordination Microparticles for Targeted Inflammatory Bowel Disease Treatment"],"prefix":"10.1021","author":[{"given":"Kun","family":"Yang","sequence":"first","affiliation":[{"name":"School of Synthetic Biology and Biomanufacturing, State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education)","place":["Tianjin, P. R. China"]},{"name":"Tianjin University","place":["Tianjin, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Ren","sequence":"additional","affiliation":[{"name":"School of Synthetic Biology and Biomanufacturing, State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education)","place":["Tianjin, P. R. China"]},{"name":"Tianjin University","place":["Tianjin, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaying","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Synthetic Biology and Biomanufacturing, State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education)","place":["Tianjin, P. R. China"]},{"name":"Tianjin University","place":["Tianjin, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6166-0470","authenticated-orcid":true,"given":"Yumiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Synthetic Biology and Biomanufacturing, State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education)","place":["Tianjin, P. R. China"]},{"name":"Tianjin University","place":["Tianjin, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-025-08940-0"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)32126-2"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)02586-2"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00966-2"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nature10208"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-025-01163-0"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2019.01.022"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-024-01035-7"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.12.044"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202304023"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2023.10.028"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c05544"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-023-02097-6"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202504802"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02724-w"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02217-7"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.04.016"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20230142"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2025.2544689"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202416122"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-024-01693-9"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v054a07"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b03523"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.08.076"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5c05032"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202000973"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2021.09.016"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c03344"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201210317"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-022-01489-4"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201900761"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.ado8222"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27010048"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110486"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202301585"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1007\/s00396-025-05385-9"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202412783"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.3390\/polym15102317"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2025.160373"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-019-0462-9"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122706"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2021.11.027"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b04436"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abc0441"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103320"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2024.160460"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2020.146041"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202008987"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b12353"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41560-020-00709-1"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202107053"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202012798"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2024.08.010"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2024.11.020"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202504990"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1136\/gut.48.4.571"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b11579"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c16367"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.01.025"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-300370"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2025.103714"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-63110-0"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-56720-1"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28196918"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23063289"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202415041"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c21459"}],"container-title":["ACS Applied Bio Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.6c00539","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.6c00539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T08:43:41Z","timestamp":1783327421000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsabm.6c00539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,9]]},"references-count":67,"alternative-id":["10.1021\/acsabm.6c00539"],"URL":"https:\/\/doi.org\/10.1021\/acsabm.6c00539","relation":{},"ISSN":["2576-6422","2576-6422"],"issn-type":[{"value":"2576-6422","type":"print"},{"value":"2576-6422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,9]]},"article-number":"acsabm.6c00539"}}