{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T15:21:11Z","timestamp":1788448871011,"version":"build-2803163510"},"reference-count":68,"publisher":"American Chemical Society (ACS)","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013276","name":"Interreg","doi-asserted-by":"publisher","award":["0072_IBEROS_MAIS_1_E"],"award-info":[{"award-number":["0072_IBEROS_MAIS_1_E"]}],"id":[{"id":"10.13039\/100013276","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031478","name":"NextGenerationEU","doi-asserted-by":"publisher","award":["02\/C12-i01.01\/2022"],"award-info":[{"award-number":["02\/C12-i01.01\/2022"]}],"id":[{"id":"10.13039\/100031478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031478","name":"NextGenerationEU","doi-asserted-by":"publisher","award":["TC-C12-i01"],"award-info":[{"award-number":["TC-C12-i01"]}],"id":[{"id":"10.13039\/100031478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["02\/C12-i01.01\/2022"],"award-info":[{"award-number":["02\/C12-i01.01\/2022"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2022.08713.PTDC"],"award-info":[{"award-number":["2022.08713.PTDC"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2023.07374.CEECIND\/CP2855\/CT0006"],"award-info":[{"award-number":["2023.07374.CEECIND\/CP2855\/CT0006"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2025.04247.BDANA"],"award-info":[{"award-number":["2025.04247.BDANA"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UID\/50016\/2025"],"award-info":[{"award-number":["UID\/50016\/2025"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["22520711900"],"award-info":[{"award-number":["22520711900"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["TC-C12-i01"],"award-info":[{"award-number":["TC-C12-i01"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Burn wound treatments remain a clinical challenge due to the complexity of skin regeneration and the need for advanced biomaterials that recapitulate the native extracellular matrix (ECM). In this study, a multilayer hybrid dressing is developed by integrating a silk fibroin (SF)-based textile with a decellularized porcine small intestine (dPSI) matrix, embedded within an enzymatically crosslinked silk sericin (SS) hydrogel. This composite construct combines mechanical reinforcement, bioactivity, and bioadhesion, offering a multifunctional platform with potential for wound dressing applications. The decellularization process effectively reduced cellular content while preserving essential ECM components. The incorporation of dPSI into SS-based hydrogel results in a stable and bioactive layer, reinforced by the SF-based textile for structural integrity. The hybrid dressings exhibit favorable swelling capacity for absorbing wound exudate and demonstrate a stable degradation profile across wound-relevant pH conditions in simulated wound fluid (SWF). Tunable mechanical properties are observed depending on the orientation of the dPSI (tunica serosa or mucosa) relative to the SF-based textile. In vitro studies with human dermal fibroblasts (hDFs) confirm high cell viability, adhesion, and metabolic activity over 10 days, with enhanced proliferation in the hybrid constructs compared to dPSI alone, indicating the positive contribution of SS hydrogel in supporting cell response. These findings demonstrate that the developed multilayer hybrid construct possesses promising structural, chemical, and biological properties for application as a dressing in wound treatment.<\/jats:p>","DOI":"10.1021\/acsabm.6c00846","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:29:40Z","timestamp":1788316180000},"source":"Crossref","is-referenced-by-count":0,"title":["Engineering Biohybrid Fibrous Materials: Silk Fibroin Textiles Combined with Decellularized Porcine Small Intestine for Wound-Healing Applications"],"prefix":"10.1021","author":[{"given":"Teresa","family":"Sousa","sequence":"first","affiliation":[{"name":"Escola Superior de Biotecnologia , , Rua Diogo Botelho 1327 , ,","place":["Porto, Portugal, 4169-005"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Rosadas","sequence":"additional","affiliation":[{"name":"Escola Superior de Biotecnologia , , Rua Diogo Botelho 1327 , ,","place":["Porto, Portugal, 4169-005"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00eas","family":"Vale","sequence":"additional","affiliation":[{"name":"Escola Superior de Biotecnologia , , Rua Diogo Botelho 1327 , ,","place":["Porto, Portugal, 4169-005"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilda","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"University of Porto , , Alameda Prof. Hern\u00e2ni Monteiro , ,","place":["Porto, Portugal, 4200-319"]},{"name":"Universidade do Porto , , R. Alfredo Allen 208 , ,","place":["Porto, Portugal, 4200-135"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Soares","sequence":"additional","affiliation":[{"name":"University of Porto , , Alameda Prof. Hern\u00e2ni Monteiro , ,","place":["Porto, Portugal, 4200-319"]},{"name":"Universidade do Porto , , R. Alfredo Allen 208 , ,","place":["Porto, Portugal, 4200-135"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7255-3400","authenticated-orcid":true,"given":"R\u00faben F.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Universidade do Porto , , R. Alfredo Allen 208 , ,","place":["Porto, Portugal, 4200-135"]},{"name":"Universidade do Porto , , Rua Jorge de Viterbo Ferreira, 228 , ,","place":["Porto, Portugal, 4050-313"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0152-9550","authenticated-orcid":true,"given":"Xiang","family":"Yao","sequence":"additional","affiliation":[{"name":"Donghua University , , ,","place":["Shanghai, People\u2019s Republic of China, 201620"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7175-6150","authenticated-orcid":true,"given":"Yaopeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Donghua University , , ,","place":["Shanghai, People\u2019s Republic of China, 201620"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3679-0759","authenticated-orcid":true,"given":"Viviana P.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Escola Superior de Biotecnologia , , Rua Diogo Botelho 1327 , ,","place":["Porto, Portugal, 4169-005"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8012-4203","authenticated-orcid":true,"given":"Ana L.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Escola Superior de Biotecnologia , , Rua Diogo Botelho 1327 , ,","place":["Porto, Portugal, 4169-005"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"issue":"3","key":"2026090310265715600_cit1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19031338","article-title":"Burn wound healing: clinical complications, medical care, treatment, and dressing types: the current state of knowledge for clinical practice","volume":"19","author":"Markiewicz-Gospodarek","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"3","key":"2026090310265715600_cit2","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1007\/s12013-024-01402-w","article-title":"Smart dressings and their applications in chronic wound management","volume":"82","author":"Li","year":"2024","journal-title":"Cell Biochem. Biophys."},{"issue":"22","key":"2026090310265715600_cit3","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242216357","article-title":"An overview of recent developments in the management of burn injuries","volume":"24","author":"Radzikowska-B\u00fcchner","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"18","key":"2026090310265715600_cit4","doi-asserted-by":"publisher","DOI":"10.3390\/polym14183806","article-title":"Hybrid-based wound dressings: Combination of synthetic and biopolymers","volume":"14","author":"Aderibigbe","year":"2022","journal-title":"Polymers"},{"issue":"7","key":"2026090310265715600_cit5","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25073702","article-title":"Bioengineering skin substitutes for wound management\u2014perspectives and challenges","volume":"25","author":"Kondej","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"14","key":"2026090310265715600_cit6","doi-asserted-by":"publisher","DOI":"10.3390\/cells14141076","article-title":"Design and applications of extracellular matrix scaffolds in tissue engineering and regeneration","volume":"14","author":"Mangani","year":"2025","journal-title":"Cells"},{"issue":"7","key":"2026090310265715600_cit7","doi-asserted-by":"publisher","DOI":"10.3390\/gels10070439","article-title":"Streamlining skin regeneration: a ready-to-use silk bilayer wound dressing","volume":"10","author":"Veiga","year":"2024","journal-title":"Gels"},{"key":"2026090310265715600_cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2025.114916","article-title":"Biofunctional Silk Sericin Hydrogels: a Versatile Platform with Potential for Tissue Healing and Regeneration","volume":"255","author":"Veiga","year":"2025","journal-title":"Colloids Surf. B"},{"issue":"1","key":"2026090310265715600_cit9","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9069924","article-title":"Silk fibroin: a promising tool for wound healing and skin regeneration","volume":"2021","author":"Vidya","year":"2021","journal-title":"Int. J. Polym. Sci."},{"issue":"4","key":"2026090310265715600_cit10","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1021\/acsbiomaterials.0c01745","article-title":"In situ forming silk sericin-based hydrogel: A novel wound healing biomaterial","volume":"7","author":"Baptista-Silva","year":"2021","journal-title":"ACS Biomater. Sci. Eng."},{"key":"2026090310265715600_cit11","doi-asserted-by":"publisher","DOI":"10.3389\/fmats.2023.1285948","article-title":"Decellularized dermal matrices: unleashing the potential in tissue engineering and regenerative medicine","volume":"10","author":"Rosadas","year":"2024","journal-title":"Front. Mater."},{"key":"2026090310265715600_cit12","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.821852","article-title":"Decellularized tissues for wound healing: towards closing the gap between scaffold design and effective extracellular matrix remodeling","volume":"10","author":"Solarte David","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"12","key":"2026090310265715600_cit13","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8122083","article-title":"Bioengineered skin substitutes: the role of extracellular matrix and vascularization in the healing of deep wounds","volume":"8","author":"Urciuolo","year":"2019","journal-title":"J. Clin. Med."},{"key":"2026090310265715600_cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.127810","article-title":"Multicomponent decellularized extracellular matrix of caprine small intestine submucosa based bioactive hydrogel promoting full-thickness burn wound healing in rabbits","volume":"255","author":"Singh","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"4","key":"2026090310265715600_cit15","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering7040140","article-title":"Biomechanical force prediction for lengthening of small intestine during distraction enterogenesis","volume":"7","author":"Hosseini","year":"2020","journal-title":"Bioengineering"},{"issue":"7","key":"2026090310265715600_cit16","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1002\/adhm.201500517","article-title":"Textile technologies and tissue engineering: a path toward organ weaving","volume":"5","author":"Akbari","year":"2016","journal-title":"Adv. Healthc. Mater."},{"key":"2026090310265715600_cit17","doi-asserted-by":"publisher","DOI":"10.64898\/2026.02.10.704815","article-title":"Decellularized Small Intestine for Full Thickness Burn Wound Treatment","volume":"11","author":"Silva","year":"2026","journal-title":"bioRxiv"},{"issue":"5","key":"2026090310265715600_cit18","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14861","article-title":"The importance of the simulated wound fluid composition and properties in the determination of the fluid handling performance of wound dressings","volume":"21","author":"Svensby","year":"2024","journal-title":"Int. Wound J."},{"issue":"11","key":"2026090310265715600_cit19","doi-asserted-by":"publisher","first-page":"7073","DOI":"10.1021\/acsbiomaterials.4c00976","article-title":"An in vitro macrophage response study of silk fibroin and silk fibroin\/nano-hydroxyapatite scaffolds for tissue regeneration application","volume":"10","author":"Wong","year":"2024","journal-title":"ACS Biomater. Sci. Eng."},{"issue":"6","key":"2026090310265715600_cit20","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1002\/term.2071","article-title":"Decellularization of bovine small intestinal submucosa and its use for the healing of a critical-sized full-thickness skin defect, alone and in combination with stem cells, in a small rodent model","volume":"11","author":"Parmaksiz","year":"2017","journal-title":"J. Tissue Eng. Regen. Med."},{"key":"2026090310265715600_cit21","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.biomaterials.2017.01.027","article-title":"Silk-based anisotropical 3D biotextiles for bone regeneration","volume":"123","author":"Ribeiro","year":"2017","journal-title":"Biomaterials"},{"issue":"11","key":"2026090310265715600_cit22","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10112870","article-title":"Human acellular dermal matrix in reconstructive surgery\u2014a review","volume":"10","author":"Gierek","year":"2022","journal-title":"Biomedicines"},{"issue":"10","key":"2026090310265715600_cit23","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.202400145","article-title":"Silk sericin and its effect on skin wound healing: A state of the art","volume":"24","author":"Mazurek","year":"2024","journal-title":"Macromol. Biosci."},{"issue":"6","key":"2026090310265715600_cit24","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1007\/s10029-019-01954-4","article-title":"Evaluation of decellularization protocols for production of porcine small intestine submucosa for use in abdominal wall reconstruction","volume":"24","author":"Chai","year":"2020","journal-title":"Hernia"},{"issue":"12","key":"2026090310265715600_cit25","doi-asserted-by":"publisher","first-page":"3233","DOI":"10.1016\/j.biomaterials.2011.01.057","article-title":"An overview of tissue and whole organ decellularization processes","volume":"32","author":"Crapo","year":"2011","journal-title":"Biomaterials"},{"issue":"6","key":"2026090310265715600_cit26","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1111\/iep.12492","article-title":"Optimization of decellularization methods using human small intestinal submucosa for scaffold generation in regenerative medicine","volume":"104","author":"Mineta","year":"2023","journal-title":"Int. J. Exp. Pathol."},{"issue":"1","key":"2026090310265715600_cit27","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-49575-2","article-title":"The impact of decellularization methods on extracellular matrix derived hydrogels","volume":"9","author":"Fern\u00e1ndez-P\u00e9rez","year":"2019","journal-title":"Sci. Rep."},{"key":"2026090310265715600_cit28","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.805299","article-title":"Decellularization in tissue engineering and regenerative medicine: evaluation, modification, and application methods","volume":"10","author":"Neishabouri","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"2026090310265715600_cit29","doi-asserted-by":"publisher","DOI":"10.1088\/1742-6596\/1697\/1\/012053","article-title":"Molecular and fibrillar structure collagen analysis by FTIR spectroscopy","volume-title":"J. Phys. Conf. Ser.","author":"Nashchekina","year":"2020"},{"issue":"5","key":"2026090310265715600_cit30","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23052826","article-title":"Porcine small intestinal submucosa (SIS) as a suitable scaffold for the creation of a tissue-engineered urinary conduit: decellularization, biomechanical and biocompatibility characterization using new approaches","volume":"23","author":"Casarin","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"2026090310265715600_cit31","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.bioactmat.2021.09.014","article-title":"Decellularized extracellular matrix scaffolds: Recent trends and emerging strategies in tissue engineering","volume":"10","author":"Zhang","year":"2022","journal-title":"Bioact. Mater."},{"issue":"1","key":"2026090310265715600_cit32","doi-asserted-by":"publisher","DOI":"10.3390\/md22010009","article-title":"Chondroitin sulfate\/dermatan sulfate hybrid chains from swim bladder: Isolation, structural analysis, and anticoagulant activity","volume":"22","author":"Yao","year":"2023","journal-title":"Mar. Drugs"},{"key":"2026090310265715600_cit33","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.actbio.2018.03.047","article-title":"Combinatory approach for developing silk fibroin scaffolds for cartilage regeneration","volume":"72","author":"Ribeiro","year":"2018","journal-title":"Acta Biomater."},{"issue":"4","key":"2026090310265715600_cit34","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14040697","article-title":"Bioinspired silk fibroin-based composite grafts as bone tunnel fillers for anterior cruciate ligament reconstruction","volume":"14","author":"Ribeiro","year":"2022","journal-title":"Pharmaceutics"},{"issue":"6","key":"2026090310265715600_cit35","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/s40257-013-0046-4","article-title":"Wound dressings: selecting the most appropriate type","volume":"14","author":"Broussard","year":"2013","journal-title":"Am. J. Clin. Dermatol."},{"issue":"3","key":"2026090310265715600_cit36","doi-asserted-by":"publisher","DOI":"10.3390\/molecules30030715","article-title":"Silk Sericin-Based Electrospun Nanofibers Forming Films for Cosmetic Applications: Preparation, Characterization, and Efficacy Evaluation","volume":"30","author":"Dragojlov","year":"2025","journal-title":"Molecules"},{"issue":"8","key":"2026090310265715600_cit37","doi-asserted-by":"publisher","first-page":"5509","DOI":"10.1039\/D2RA07673J","article-title":"Biomedical materials for wound dressing: recent advances and applications","volume":"13","author":"Nguyen","year":"2023","journal-title":"RSC Adv."},{"issue":"29","key":"2026090310265715600_cit38","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202515854","article-title":"Self-adaptive wound dressings for wound healing and repair","volume":"38","author":"Zhao","year":"2026","journal-title":"Adv. Mater."},{"issue":"5","key":"2026090310265715600_cit39","doi-asserted-by":"publisher","DOI":"10.3390\/biom10050710","article-title":"Zinc oxide nanoparticles functionalized on hydrogel grafted silk fibroin fabrics as efficient composite dressing","volume":"10","author":"Majumder","year":"2020","journal-title":"Biomolecules"},{"issue":"26","key":"2026090310265715600_cit40","doi-asserted-by":"publisher","first-page":"6351","DOI":"10.1039\/D4TB00112E","article-title":"Dry and wet wrinkling of a silk fibroin biopolymer by a shape-memory material with insight into mechanical effects on secondary structures in the silk network","volume":"12","author":"Oguntade","year":"2024","journal-title":"J. Mater. Chem. B"},{"issue":"4","key":"2026090310265715600_cit41","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1177\/0954411918759801","article-title":"Skin mechanical properties and modeling: A review","volume":"232","author":"Joodaki","year":"2018","journal-title":"Proc. Inst. Mech. Eng. H"},{"issue":"4","key":"2026090310265715600_cit42","doi-asserted-by":"publisher","DOI":"10.1080\/21688370.2023.2290940","article-title":"Decellularized small intestine scaffolds: a potential xenograft for restoration of intestinal perforation","volume":"12","author":"Tardalkar","year":"2024","journal-title":"Tissue Barriers"},{"issue":"2","key":"2026090310265715600_cit43","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1007\/s10561-024-10131-6","article-title":"Development and validation of cryopreserved or freeze-dried decellularized human dermis for transplantation","volume":"25","author":"Montagner","year":"2024","journal-title":"Cell Tissue Bank."},{"issue":"1","key":"2026090310265715600_cit44","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1002\/jbm.a.30268","article-title":"Physical characteristics of small intestinal submucosa scaffolds are location-dependent","volume":"73","author":"Raghavan","year":"2005","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"9","key":"2026090310265715600_cit45","doi-asserted-by":"publisher","first-page":"6902","DOI":"10.1039\/D4RA08014A","article-title":"A hybrid scaffold of modified human amniotic membrane with gelatine\/dendrimer-protected silver nanoparticles for skin wound healing applications","volume":"15","author":"Khalili","year":"2025","journal-title":"RSC Adv."},{"issue":"1","key":"2026090310265715600_cit46","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-024-03013-3","article-title":"Mupirocin-doped \u03b1-cellulose nanopaper for wound dressing: development, in vitro characterization and antimicrobial studies","volume":"26","author":"Pant","year":"2024","journal-title":"AAPS PharmSciTech"},{"issue":"2","key":"2026090310265715600_cit47","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s42114-025-01295-0","article-title":"DNA-collagen dressing for promoting scarless healing in early burn wound management","volume":"8","author":"Song","year":"2025","journal-title":"Adv. Compos. Hybrid Mater."},{"issue":"4","key":"2026090310265715600_cit48","doi-asserted-by":"publisher","DOI":"10.4172\/2169-0022.1000254","article-title":"Mechanical behaviour of skin: a review","volume":"5","author":"Kalra","year":"2016","journal-title":"J. Mater. Sci. Eng"},{"issue":"6","key":"2026090310265715600_cit49","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1111\/iwj.13733","article-title":"The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review","volume":"19","author":"Derwin","year":"2022","journal-title":"Int. Wound J."},{"issue":"31","key":"2026090310265715600_cit50","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202400827","article-title":"An environmentally stable, biocompatible, and multilayered wound dressing film with reversible and strong adhesion","volume":"13","author":"Chen","year":"2024","journal-title":"Adv. Healthc. Mater."},{"key":"2026090310265715600_cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.143127","article-title":"Scalable nanofibrous silk fibroin textile with excellent Mie scattering and high sweat evaporation ability for highly efficient passive personal thermal management","volume":"466","author":"He","year":"2023","journal-title":"Chem. Eng. J."},{"issue":"12","key":"2026090310265715600_cit52","doi-asserted-by":"publisher","first-page":"6536","DOI":"10.1007\/s10853-022-07056-4","article-title":"Dressings for burn wound: a review","volume":"57","author":"Noor","year":"2022","journal-title":"J. Mater. Sci."},{"issue":"3","key":"2026090310265715600_cit53","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/0305-4179(77)90004-3","article-title":"The evaporative water loss from burns and the water-vapour permeability of grafts and artificial membranes used in the treatment of burns","volume":"3","author":"Lamke","year":"1977","journal-title":"Burns"},{"issue":"2","key":"2026090310265715600_cit54","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/s12221-011-0207-0","article-title":"Electrospun in-situ hybrid polyurethane\/nano-TiO2 as wound dressings","volume":"12","author":"Yan","year":"2011","journal-title":"Fibers Polym."},{"key":"2026090310265715600_cit55","doi-asserted-by":"publisher","DOI":"10.1093\/burnst\/tkac024","article-title":"Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study","volume":"10","author":"Minsart","year":"2022","journal-title":"Burns Trauma"},{"issue":"12","key":"2026090310265715600_cit56","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1089\/wound.2020.1232","article-title":"Moist wound healing with commonly available dressings","volume":"10","author":"Nuutila","year":"2021","journal-title":"Adv. Wound Care"},{"issue":"4","key":"2026090310265715600_cit57","doi-asserted-by":"publisher","first-page":"3781","DOI":"10.1021\/acsami.8b21259","article-title":"Enzymatically cross-linked silk fibroin-based hierarchical scaffolds for osteochondral regeneration","volume":"11","author":"Ribeiro","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"11","key":"2026090310265715600_cit58","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0049215","article-title":"Effects of hydrogen peroxide on wound healing in mice in relation to oxidative damage","volume":"7","author":"Loo","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"2026090310265715600_cit59","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1111\/wrr.12125","article-title":"The effects of pH on wound healing, biofilms, and antimicrobial efficacy","volume":"22","author":"Percival","year":"2014","journal-title":"Wound Repair Regen."},{"issue":"2","key":"2026090310265715600_cit60","doi-asserted-by":"publisher","first-page":"53","DOI":"10.12968\/jowc.2014.23.2.53","article-title":"The influence of different dressings on the pH of the wound environment","volume":"23","author":"Milne","year":"2014","journal-title":"J. Wound Care"},{"issue":"21","key":"2026090310265715600_cit61","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232113655","article-title":"Influence of acidic pH on wound healing in vivo: a novel perspective for wound treatment","volume":"23","author":"Sim","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"2026090310265715600_cit62","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.actbio.2019.11.050","article-title":"Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside","volume":"103","author":"Chouhan","year":"2020","journal-title":"Acta Biomater."},{"issue":"24-25","key":"2026090310265715600_cit63","doi-asserted-by":"publisher","first-page":"3415","DOI":"10.1016\/j.biomaterials.2008.05.002","article-title":"In vivo degradation of three-dimensional silk fibroin scaffolds","volume":"29","author":"Wang","year":"2008","journal-title":"Biomaterials"},{"key":"2026090310265715600_cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111752","article-title":"Fabrication of 3D hybrid scaffold by combination technique of electrospinning-like and freeze-drying to create mechanotransduction signals and mimic extracellular matrix function of skin","volume":"120","author":"Aghmiuni","year":"2021","journal-title":"Mater. Sci. Eng. C"},{"issue":"24","key":"2026090310265715600_cit65","doi-asserted-by":"publisher","DOI":"10.3390\/ijms262411764","article-title":"Anti-Fibrotic Properties of a Decellularized Extracellular Matrix Scaffold from Porcine Small Intestinal Submucosa in Normal Human and Keloid Fibroblasts","volume":"26","author":"Banerjee","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"2026090310265715600_cit66","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-024-09465-x","article-title":"Reinforcing decellularized small intestine submucosa with cellulose acetate nanofibrous and silver nanoparticles as a scaffold for wound healing applications","volume":"51","author":"Zavareh","year":"2024","journal-title":"Mol. Biol. Rep."},{"issue":"9","key":"2026090310265715600_cit67","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10092213","article-title":"Porcine small intestinal submucosa alters the biochemical properties of wound healing: a narrative review","volume":"10","author":"Fujii","year":"2022","journal-title":"Biomedicines"},{"issue":"22","key":"2026090310265715600_cit68","doi-asserted-by":"publisher","first-page":"16748","DOI":"10.1039\/C4RA16146G","article-title":"Tough and VEGF-releasing scaffolds composed of artificial silk fibroin mats and a natural acellular matrix","volume":"5","author":"Li","year":"2015","journal-title":"RSC Adv."}],"container-title":["ACS Applied Bio Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsabm.6c00846","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/aabmcb\/article-pdf\/doi\/10.1021\/acsabm.6c00846\/67587483\/mt-2026-00846f.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/aabmcb\/article-pdf\/doi\/10.1021\/acsabm.6c00846\/67587483\/mt-2026-00846f.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:50:42Z","timestamp":1788447042000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/aabmcb\/article\/doi\/10.1021\/acsabm.6c00846\/5347616\/Engineering-Biohybrid-Fibrous-Materials-Silk"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,28]]},"references-count":68,"URL":"https:\/\/doi.org\/10.1021\/acsabm.6c00846","relation":{},"ISSN":["2576-6422"],"issn-type":[{"value":"2576-6422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,28]]}}}