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In this study, we developed a visualized multifunctional injectable sericin hydrogel wound dressing with excellent bioactivity via the crosslinking of sericin (SS) with protocatechuic aldehyde (PA). The sericin hydrogel not only features a simple fabrication process and low production cost but also demonstrates exceptional moisturizing capacity, breathability, elasticity, absorbency, and biodegradability with weakly acidic degradation byproducts. Additionally, it exhibits robust antibacterial and antioxidant capacities, high biocompatibility, and remarkable promotion of cell migration. Given its superior performance, we employed it to repair full-thickness skin wounds in a mouse model. The sericin hydrogel effectively promoted wound healing, demonstrating its potential as a multifunctional dressing for cutaneous wound management.<\/jats:p>","DOI":"10.1021\/acsabm.6c01247","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T13:13:42Z","timestamp":1785849222000},"page":"7725-7738","source":"Crossref","is-referenced-by-count":0,"title":["A Visualizable Injectable Multifunctional Sericin Hydrogel with Facile Fabrication for Versatile Wound Care"],"prefix":"10.1021","volume":"9","author":[{"given":"Zhanyan","family":"Du","sequence":"first","affiliation":[{"name":"Jiangsu University of Science and Technology , , , ,","place":["Zhenjiang, Jiangsu, China, 212100"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongkang","family":"Wei","sequence":"additional","affiliation":[{"name":"Jiangsu University of Science and Technology , , , ,","place":["Zhenjiang, Jiangsu, China, 212100"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyu","family":"Wu","sequence":"additional","affiliation":[{"name":"Changsha Medical University , , ,","place":["Changsha, China, 410219"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingfei","family":"Li","sequence":"additional","affiliation":[{"name":"Jiangsu University of Science and Technology , , , ,","place":["Zhenjiang, Jiangsu, China, 212100"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guozheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jiangsu University of Science and Technology , , , ,","place":["Zhenjiang, Jiangsu, China, 212100"]},{"name":"Chinese Academy of Agricultural Sciences , , ,","place":["Zhenjiang, China, 212100"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8166-8448","authenticated-orcid":true,"given":"Yeshun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jiangsu University of Science and Technology , , , ,","place":["Zhenjiang, Jiangsu, China, 212100"]},{"name":"Chinese Academy of Agricultural Sciences , , ,","place":["Zhenjiang, China, 212100"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"key":"2026081707172151300_cit1","doi-asserted-by":"crossref","first-page":"1154301","DOI":"10.3389\/fbioe.2023.1154301","article-title":"Applications of MXene and its modified materials in skin wound repair","volume":"11","author":"Zhang","year":"2023","journal-title":"Front. 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