{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T08:56:24Z","timestamp":1773651384670,"version":"3.50.1"},"reference-count":69,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100031478","name":"NextGenerationEU","doi-asserted-by":"publisher","award":["CN00000022"],"award-info":[{"award-number":["CN00000022"]}],"id":[{"id":"10.13039\/100031478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Agric. Sci. Technol."],"published-print":{"date-parts":[[2026,3,16]]},"DOI":"10.1021\/acsagscitech.5c01031","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T17:14:13Z","timestamp":1770311653000},"page":"539-550","source":"Crossref","is-referenced-by-count":0,"title":["Animal Dietary Exposure to Methylxanthines through the Inclusion of Former Food Products (FFPs) in Feed"],"prefix":"10.1021","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1785-0437","authenticated-orcid":true,"given":"Francesca","family":"Mercogliano","sequence":"first","affiliation":[{"name":"Department of Pharmacological and Biomolecular Sciences, Universit\u00e0 degli Studi di Milano, via Balzaretti 9, Milano 20133, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Di Lorenzo","sequence":"additional","affiliation":[{"name":"Department of Pharmacological and Biomolecular Sciences, Universit\u00e0 degli Studi di Milano, via Balzaretti 9, Milano 20133, Italy"},{"name":"Coordinated Research Center (CRC) \u201cInnovation for Well-Being and Environment\u201d","place":["Milan, Italy"]},{"name":"Universit\u00e0 degli Studi di Milano","place":["Milan, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3317-4384","authenticated-orcid":true,"given":"Marco","family":"Tretola","sequence":"additional","affiliation":[{"name":"Institute for Livestock Sciences, Agroscope, La Tioleyre 4, Posieux 1725, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9736-8746","authenticated-orcid":true,"given":"Corinne","family":"Bani","sequence":"additional","affiliation":[{"name":"Department of Pharmacological and Biomolecular Sciences, Universit\u00e0 degli Studi di Milano, via Balzaretti 9, Milano 20133, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Manoni","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Animal Sciences, Universit\u00e0 degli Studi di Milano, via dell\u2019Universit\u00e0 6, Lodi 26900, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0337-9426","authenticated-orcid":true,"given":"Luciano","family":"Pinotti","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Animal Sciences, Universit\u00e0 degli Studi di Milano, via dell\u2019Universit\u00e0 6, Lodi 26900, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fochx.2025.102604"},{"key":"ref2\/cit2","author":"Food and Agriculture Organization of the United Nations (FAO)","year":"2024","journal-title":"Evaluation of FAO\u2019s Work on Reducing Food Loss and Waste under Programme Priority Area \u201cBetter Nutrition 4.\u201d"},{"key":"ref3\/cit3","first-page":"1","volume":"29","author":"European Commission","year":"2013","journal-title":"Off. J. Eur. Union"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclepro.2021.126290"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3390\/su142113911"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3390\/foods13203273"},{"key":"ref7\/cit7","volume":"133","author":"European Commission","year":"2018","journal-title":"Off. J. Eur. Union"},{"key":"ref8\/cit8","volume":"150","author":"European Parliament and Council","year":"2018","journal-title":"Off. J. Eur. Union"},{"key":"ref9\/cit9","author":"European Commission","year":"2021","journal-title":"Publ. Off. J. Eur. Union"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21080974"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.13469"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-13443-2_7"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3109\/10408448209037495"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.2527\/1997.752423x"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/fes3.70003"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3390\/nu12041123"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(99)00533-6"},{"key":"ref18\/cit18","volume":"140","author":"European Parliament and Council of the European Union","year":"2019","journal-title":"Off. J. Eur. Union"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2008.725"},{"key":"ref20\/cit20","volume":"308","author":"European Commission","year":"2009","journal-title":"Off. J. Eur. Union"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.32854\/agrop.v15i9.2171"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.22456\/1679-9216.98955"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1080\/1828051X.2019.1607784"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.23751\/pn.v23i3.10347"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.101019"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjnut.2024.07.032"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.14087"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-70310-z"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2025.101477"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.13830"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2025.101512"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.resconrec.2025.108536"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.resconrec.2014.03.008"},{"key":"ref34\/cit34","volume":"35","author":"European Parliament and Council of the European Union","year":"2005","journal-title":"Off. J. Eur. Union"},{"key":"ref35\/cit35","volume":"229","author":"European Parliament and Council of the European Union","year":"2009","journal-title":"Off. J. Eur. Union"},{"key":"ref36\/cit36","unstructured":"European Former\nFoodstuff Processors\nAssociation.\n                      Feed safety\n                      . https:\/\/effpa.eu\/our-focuses\/feed-safety\/."},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1111\/aab.12676"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclepro.2018.02.030"},{"key":"ref39\/cit39","volume-title":"Official methods of analysis","author":"Association of Official Analytical Chemists","year":"2005","edition":"18"},{"key":"ref40\/cit40","author":"European Commission","year":"2009","journal-title":"Off. J. Eur. Union"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1080\/19440049.2017.1306884"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1080\/1828051X.2019.1596758"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.4103\/2229-4708.84436"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/toxins17090441"},{"key":"ref45\/cit45","unstructured":"Food and Drug Administration.\n                      Bioanalytical Method Validation: Guidance\nfor Industry\n                      ; U.S. Department of Health and\nHuman Services: Silver Spring, MD, 2018, pp 44 https:\/\/www.fda.gov\/files\/drugs\/published\/Bioanalytical-Method-Validation-Guidance-for-Industry.pdf"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2017.5021"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2024.8858"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2020-18425"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2020-19998"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3390\/ani10010125"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.100918"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.3390\/ani11113315"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-024-32695-2"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2018.11.072"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e24544"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.3390\/nu5104159"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2018-16176"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2019.5896"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.2903\/sp.efsa.2024.EN-9036"},{"key":"ref60\/cit60","volume-title":"Bulletin\/Vermont Agricultural Experiment Station; 272","author":"Aplin R. D.","year":"1927"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1002\/jctb.5000560202"},{"issue":"10","key":"ref62\/cit62","first-page":"313","volume":"90","author":"Curtis P. E.","year":"1972","journal-title":"Vet. Rec."},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015638903740"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.848452"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2021.100243"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2019-17550"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1016\/S0372-5545(17)33002-X"},{"issue":"1","key":"ref68\/cit68","first-page":"18","volume":"29","author":"Ogunsipe M. H.","year":"2017","journal-title":"Livest. Res. Rural Dev."},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.5b05732"}],"container-title":["ACS Agricultural Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsagscitech.5c01031","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsagscitech.5c01031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T08:10:22Z","timestamp":1773648622000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsagscitech.5c01031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,5]]},"references-count":69,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3,16]]}},"alternative-id":["10.1021\/acsagscitech.5c01031"],"URL":"https:\/\/doi.org\/10.1021\/acsagscitech.5c01031","relation":{},"ISSN":["2692-1952","2692-1952"],"issn-type":[{"value":"2692-1952","type":"print"},{"value":"2692-1952","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,5]]}}}