{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:30:38Z","timestamp":1786995038674,"version":"build-2736575974"},"reference-count":61,"publisher":"American Chemical Society (ACS)","issue":"42","license":[{"start":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T00:00:00Z","timestamp":1601251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T00:00:00Z","timestamp":1601251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T00:00:00Z","timestamp":1601251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of?Hunan Province","doi-asserted-by":"publisher","award":["2018JJ2385"],"award-info":[{"award-number":["2018JJ2385"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009377","name":"Education Department of Hunan Province","doi-asserted-by":"publisher","award":["19A479"],"award-info":[{"award-number":["19A479"]}],"id":[{"id":"10.13039\/100009377","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21775133"],"award-info":[{"award-number":["21775133"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21874114"],"award-info":[{"award-number":["21874114"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hunan Province","award":["2019JGYB113"],"award-info":[{"award-number":["2019JGYB113"]}]},{"name":"Hunan Province","award":["CX20190483"],"award-info":[{"award-number":["CX20190483"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Adenosine triphosphate (ATP) is mainly produced in mitochondria and plays an important role in lots of pathological processes such as colitis. Unfortunately, to date, few suitable fluorescence probes have been developed for monitoring the ATP level in colitis. Herein, a fluorescence nanoprobe named NIR@ZIF-90 is proposed and prepared by encapsulating a rhodamine-based near-infrared (NIR) dye into zeolitic imidazolate frameworks (ZIF-90). The nanoprobe is nonfluorescent because the emission of NIR is suppressed by the encapsulation, while in the presence of ATP, the framework of ZIF-90 is dissembled to release NIR and thus NIR fluorescence at 750 nm is observed. The nanoprobe shows high sensitivity to ATP with a 72-fold increase and excellent selectivity to ATP over other nucleotides. Moreover, with low cytotoxicity and good mitochondria-targeted ability, NIR@ZIF-90 is used to image ATP in colorectal cancer cells (HCT116). In addition, due to the NIR emission, the nanoprobe is further employed to successfully monitor the ATP level in a colitis mouse model. To the best of our knowledge, the nanoprobe is the first example to study colitis in vivo with the guidance of ATP, which will provide an efficient tool for understanding colitis.<\/jats:p>","DOI":"10.1021\/acsami.0c13003","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T03:48:30Z","timestamp":1601264910000},"page":"47840-47847","source":"Crossref","is-referenced-by-count":47,"title":["Near-Infrared\nFluorescence MOF Nanoprobe for Adenosine\nTriphosphate-Guided Imaging in Colitis"],"prefix":"10.1021","volume":"12","author":[{"given":"Yi-Ting","family":"Zhao","sequence":"first","affiliation":[{"name":"Xiangtan University , , ,","place":["Xiangtan, P. R. China, 411105"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi-Xi","family":"Chen","sequence":"additional","affiliation":[{"name":"Xiangtan University , , ,","place":["Xiangtan, P. R. China, 411105"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Li","family":"Jiang","sequence":"additional","affiliation":[{"name":"Xiangtan University , , ,","place":["Xiangtan, P. R. China, 411105"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7206-2564","authenticated-orcid":true,"given":"Yongfei","family":"Li","sequence":"additional","affiliation":[{"name":"Xiangtan University , , ,","place":["Xiangtan, P. R. China, 411105"]},{"name":"Xiangtan University , , ,","place":["Xiangtan, P. R. China, 411105"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Fei","sequence":"additional","affiliation":[{"name":"Xiangtan University , , ,","place":["Xiangtan, P. R. China, 411105"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8382-5264","authenticated-orcid":true,"given":"Chun-Yan","family":"Li","sequence":"additional","affiliation":[{"name":"Xiangtan University , , ,","place":["Xiangtan, P. R. China, 411105"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2020,9,28]]},"reference":[{"key":"2026081714130093600_cit1","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1038\/nprot.2017.052","article-title":"Use of Luciferase Probes to Measure\nATP in Living Cells and Animals","volume":"12","author":"Morciano","year":"2017","journal-title":"Nat. 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Mater."},{"key":"2026081714130093600_cit33","doi-asserted-by":"publisher","first-page":"4291","DOI":"10.1039\/C7NR07949D","article-title":"Early Stage Structural Development of Prototypical\nZeolitic Imidazolate Framework (ZIF) in Solution","volume":"10","author":"Terban","year":"2018","journal-title":"Nanoscale"},{"key":"2026081714130093600_cit34","doi-asserted-by":"publisher","first-page":"10186","DOI":"10.1073\/pnas.0602439103","article-title":"Exceptional\nChemical and Thermal Stability of Zeolitic\nImidazolate Frameworks","volume":"103","author":"Park","year":"2006","journal-title":"Proc. Natl. Acad. Sci.\nU.S.A."},{"key":"2026081714130093600_cit35","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.seppur.2018.03.015","article-title":"Viscosity-Driven In\nSitu Self-Assembly Strategy to Fabricate Cross-Linked ZIF-90\/PVA Hybrid\nMembranes For Ethanol Dehydration Via Pervaporation","volume":"201","author":"Wei","year":"2018","journal-title":"Sep. Purif. 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