{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:56:24Z","timestamp":1787000184105,"version":"build-2736575974"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T00:00:00Z","timestamp":1615161600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T00:00:00Z","timestamp":1615161600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T00:00:00Z","timestamp":1615161600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["2U54GM104942-02"],"award-info":[{"award-number":["2U54GM104942-02"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["P20GM103434"],"award-info":[{"award-number":["P20GM103434"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["P20GM109098"],"award-info":[{"award-number":["P20GM109098"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["P30GM103488"],"award-info":[{"award-number":["P30GM103488"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["U57GM104942"],"award-info":[{"award-number":["U57GM104942"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Office of the Assistant Secretary of Defense for Health Affairs","award":["W81XWH1710603"],"award-info":[{"award-number":["W81XWH1710603"]}]},{"name":"Office of the Assistant Secretary of Defense for Health Affairs","award":["W81XWH1810203"],"award-info":[{"award-number":["W81XWH1810203"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2021,3,17]]},"DOI":"10.1021\/acsami.0c20332","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T12:13:35Z","timestamp":1615205615000},"page":"12454-12462","source":"Crossref","is-referenced-by-count":19,"title":["Programmed Multidrug Delivery Based on Bio-Inspired Capsule-Integrated Nanocoatings for Infected Bone Defect Treatment"],"prefix":"10.1021","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2778-1751","authenticated-orcid":true,"given":"Shichao","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Vaida","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josh","family":"Parenti","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brock A.","family":"Lindsey","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3547-0462","authenticated-orcid":true,"given":"Malcolm","family":"Xing","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, University of Manitoba, and the Children\u2019s Hospital Research Institute of Manitoba, Winnipeg, Manitoba R3E 3P4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5766-5666","authenticated-orcid":true,"given":"Bingyun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,3,8]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1097\/bot.0000000000001397"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.5435\/jaaos-22-01-57"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1097\/ta.0b013e318250bfb4"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1097\/ta.0b013e318163b875"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200600001-00008"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-019-01217-y"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2016.34"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.5435\/jaaos-d-18-00193"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0019-y"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3653"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1097\/ta.0b013e318241f534"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1097\/bot.0b013e31819dfa04"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1097\/ta.0b013e318163c40b"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201801106"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201603197"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201807915"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201203370"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202002434"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b17264"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa2491"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-060418-052350"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200600113"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19061641"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cis.2020.102200"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200906266"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200901327"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b02121"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/app.43563"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201502660"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2366"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1126\/science.8097337"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1126\/science.8097338"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2012.06.036"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2012.04.004"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.11.004"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3895"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2009.01.042"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/adem.201180020"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1039\/b927207k"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3390\/polym12071469"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-011-4397-1"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/mame.201100309"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3351"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2319"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/s41558-018-0161-6"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-019-0503-9"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1177\/003335491112600309"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.memsci.2011.11.045"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1039\/c5ra04439a"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1086\/605630"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.7205\/milmed-d-03-8008"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0212-9"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1097\/ta.0b013e318163cd14"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.3390\/ijms11030789"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.0c20332","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T18:19:55Z","timestamp":1682446795000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.0c20332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,8]]},"references-count":54,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,3,17]]}},"alternative-id":["10.1021\/acsami.0c20332"],"URL":"https:\/\/doi.org\/10.1021\/acsami.0c20332","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,8]]}}}