{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:34:51Z","timestamp":1790418891704,"version":"4.1.0"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T00:00:00Z","timestamp":1615766400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T00:00:00Z","timestamp":1615766400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T00:00:00Z","timestamp":1615766400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100017330","name":"Foundation of Jiangsu Collaborative Innovation Center of Biomedical Functional Materials","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100017330","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2021,3,24]]},"DOI":"10.1021\/acsami.1c02011","type":"journal-article","created":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T13:51:32Z","timestamp":1615816292000},"page":"12960-12971","source":"Crossref","is-referenced-by-count":56,"title":["Tumor Microenvironment-Activatable Cyclic Cascade Reaction to Reinforce Multimodal Combination Therapy by Destroying the Extracellular Matrix"],"prefix":"10.1021","volume":"13","author":[{"given":"Yutian","family":"Su","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Qixia District, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xichen","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Qixia District, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liling","family":"Lei","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Qixia District, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baolei","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Qixia District, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8918-8991","authenticated-orcid":true,"given":"Shishan","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Qixia District, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9009-6151","authenticated-orcid":true,"given":"Jian","family":"Shen","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Qixia District, Nanjing 210023, China"},{"name":"National and Local Joint Engineering Research Center of Biomedical Functional Materials, Nanjing Normal University, Nanjing 210046, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,3,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2016.25"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.100851"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b18427"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201910085"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001223"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201903512"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201907568"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00029.2006"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b09871"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.7b01290"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b00495"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b04236"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.03.046"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b04847"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08670-8"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2015.09.019"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201610682"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b05042"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201808325"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1126\/science.123.3191.309"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119568"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b02188"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.7150\/thno.40439"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.5b05030"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202000897"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b13598"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201601902"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201803804"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201808306"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201800510"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16513-0"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202003338"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.119770"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202003382"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201502902"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/c8sc04844d"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b01818"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2009.04.003"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b05559"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201504532"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2020.125949"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.4065\/82.7.864"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.7150\/thno.42661"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201902885"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201906985"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b06175"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.10.030"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b08737"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2011.09.007"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1126\/science.1067100"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1821"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202002439"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.1c02011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T12:29:30Z","timestamp":1682598570000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.1c02011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,15]]},"references-count":52,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,3,24]]}},"alternative-id":["10.1021\/acsami.1c02011"],"URL":"https:\/\/doi.org\/10.1021\/acsami.1c02011","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,15]]}}}