{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T17:16:24Z","timestamp":1778865384080,"version":"3.51.4"},"reference-count":69,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T00:00:00Z","timestamp":1642723200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T00:00:00Z","timestamp":1642723200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T00:00:00Z","timestamp":1642723200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100008875","name":"University of Akron","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008875","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2022,2,2]]},"DOI":"10.1021\/acsami.1c19962","type":"journal-article","created":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T16:48:42Z","timestamp":1642783722000},"page":"4899-4913","source":"Crossref","is-referenced-by-count":14,"title":["Generation of Oxygenating Fluorinated Methacrylamide Chitosan Microparticles to Increase Cell Survival and Function in Large Liver Spheroids"],"prefix":"10.1021","volume":"14","author":[{"given":"Mona","family":"Mansouri","sequence":"first","affiliation":[{"name":"Department of Chemical, Biomolecular, and Corrosion Engineering, University of Akron, 200 E Buchtel Avenue, Akron, Ohio 44325, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha","family":"Beemer","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Akron, 235 Carroll Street, Akron, Ohio 44325, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8450-0640","authenticated-orcid":true,"given":"Chandrasekhar R.","family":"Kothapalli","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biomedical Engineering, Cleveland State University, 2121 Euclid Avenue, Cleveland, Ohio 44115, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyler","family":"Rhoades","sequence":"additional","affiliation":[{"name":"Department of Physics, Cleveland State University, 2121 Euclid Avenue, Cleveland, Ohio 44115, Unied States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petru S.","family":"Fodor","sequence":"additional","affiliation":[{"name":"Department of Physics, Cleveland State University, 2121 Euclid Avenue, Cleveland, Ohio 44115, Unied States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dola","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9620 Carnegie Avenue, Cleveland, Ohio 44106, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6356-7691","authenticated-orcid":true,"given":"Nic D.","family":"Leipzig","sequence":"additional","affiliation":[{"name":"Department of Chemical, Biomolecular, and Corrosion Engineering, University of Akron, 200 E Buchtel Avenue, Akron, Ohio 44325, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2022,1,21]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0048837"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/bit.20086"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2018.0256"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21029-2"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","unstructured":"Altschuler, S. J.; Wu, L. F. Cellular Heterogeneity: Do Differences Make a Difference? Cell; Elsevier B.V., 2010; pp 559\u2013563.","DOI":"10.1016\/j.cell.2010.04.033"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2009.0042"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2019.00221"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2017.08.003"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3390\/cells8060525"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/srep02863"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2019.00265"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1159\/000091096"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.47162\/RJME.61.3.01"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.00709"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering6030059"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3390\/gels3030027"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.0c00338"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2012.10.034"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2016.03.022"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0203371"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.201900250"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-013-0925-0"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1142\/s0219519418500021"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2005.04.007"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.3390\/ani10010030"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-2074-7_27"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1242\/dev.166884"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201004275"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200702663"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2016.11.092"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-23064-4"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2015.07.023"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1186\/s11671-018-2457-x"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3390\/toxics8040112"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1039\/c5ib00170f"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.00911"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.07.028"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.11.026"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/srep25329"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-021-01853-8"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2013.153"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-019-1283-0"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/srep36750"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20071629"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-63621-4"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2007.0434"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.3390\/mi11010036"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0138655"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0086365"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1113560109"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-41273-3"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-1598"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/srep25187"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201801825"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2008.0403"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1039\/c8lc00333e"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0229106"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2013.03.008"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2016.0877"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2011.0478"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.m113.544494"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-6788-9_2"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.3390\/md15040105"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-27686-6"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1172\/jci66369"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00013.2007"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12412-1"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3319-0"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201600644"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.1c19962","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T14:30:54Z","timestamp":1682260254000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.1c19962"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,21]]},"references-count":69,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,2,2]]}},"alternative-id":["10.1021\/acsami.1c19962"],"URL":"https:\/\/doi.org\/10.1021\/acsami.1c19962","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,21]]}}}