{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:48:44Z","timestamp":1790196524843,"version":"4.1.0"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"18","license":[{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81401506"],"award-info":[{"award-number":["81401506"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81873924"],"award-info":[{"award-number":["81873924"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971131"],"award-info":[{"award-number":["81971131"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Changzhou Health Committee","award":["CJ20210068"],"award-info":[{"award-number":["CJ20210068"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2022,5,11]]},"DOI":"10.1021\/acsami.1c23737","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T13:05:03Z","timestamp":1651064703000},"page":"20551-20565","source":"Crossref","is-referenced-by-count":35,"title":["Hypoxia-Responsive Stereocomplex Polymeric Micelles with Improved Drug Loading Inhibit Breast Cancer Metastasis in an Orthotopic Murine Model"],"prefix":"10.1021","volume":"14","author":[{"given":"Min","family":"Lu","sequence":"first","affiliation":[{"name":"Institute of Special Environmental Medicine and Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Huang","sequence":"additional","affiliation":[{"name":"Institute of Special Environmental Medicine and Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohui","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Hematology, Nanjing Medical University, Affiliated Changzhou No. 2 People\u2019s Hospital, Changzhou 213000, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajia","family":"Sun","sequence":"additional","affiliation":[{"name":"Institute of Special Environmental Medicine and Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Special Environmental Medicine and Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyan","family":"Weng","sequence":"additional","affiliation":[{"name":"Institute of Special Environmental Medicine and Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Special Environmental Medicine and Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Luo","sequence":"additional","affiliation":[{"name":"Institute of Special Environmental Medicine and Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3344-1449","authenticated-orcid":true,"given":"Zhongping","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Special Environmental Medicine and Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,4,27]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21590"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2020.101662"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-020-00649-8"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2020.09.009"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00202"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2020.11.029"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-019-03910-6"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.06.012"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2013.02.009"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC03153A"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2016.05.003"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2019.110464"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2020.00688"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.02.017"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b04205"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.7150\/thno.26161"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.11.008"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.07.061"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S158696"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.12.041"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.7150\/thno.38069"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2020.05.032"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.10.029"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1166\/nnl.2020.3247"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2021.04.035"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2019.01.110"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1039\/C5PY00091B"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c09519"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c11265"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c14686"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2021.02.061"},{"key":"ref32\/cit32","volume-title":"Oligo (Lactic Acid)[N] Prodrugs for Poly(Ethylene Glycol)-Block-Poly(D,L-Lactic Acid) Micelles in Drug Delivery","author":"Tam Y. T.","year":"2018"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/ma034734i"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA08699A"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/polym8040165"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/nl048037v"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.102979"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC00462A"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.08.004"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2020.00193"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.01.021"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c14405"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.01.026"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2015.01.011"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1172\/JCI40252"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.1c23737","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.1c23737","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T20:04:05Z","timestamp":1682539445000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.1c23737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,27]]},"references-count":45,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2022,5,11]]}},"alternative-id":["10.1021\/acsami.1c23737"],"URL":"https:\/\/doi.org\/10.1021\/acsami.1c23737","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,27]]}}}