{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:16:32Z","timestamp":1790946992633,"version":"4.1.0"},"reference-count":70,"publisher":"American Chemical Society (ACS)","issue":"17","license":[{"start":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T00:00:00Z","timestamp":1650326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T00:00:00Z","timestamp":1650326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T00:00:00Z","timestamp":1650326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["20-14-00155"],"award-info":[{"award-number":["20-14-00155"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2022,5,4]]},"DOI":"10.1021\/acsami.2c03210","type":"journal-article","created":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:40:55Z","timestamp":1650415255000},"page":"19241-19252","source":"Crossref","is-referenced-by-count":26,"title":["Enzyme Nanoreactor for <i>In Vivo<\/i> Detoxification of Organophosphates"],"prefix":"10.1021","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2001-1570","authenticated-orcid":true,"given":"Tatiana","family":"Pashirova","sequence":"first","affiliation":[{"name":"Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zukhra","family":"Shaihutdinova","sequence":"additional","affiliation":[{"name":"Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russian Federation"},{"name":"Biochemical Neuropharmacology Laboratory, Kazan Federal University, Kremlevskaya Str., 18, Kazan 420111, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milana","family":"Mansurova","sequence":"additional","affiliation":[{"name":"Biochemical Neuropharmacology Laboratory, Kazan Federal University, Kremlevskaya Str., 18, Kazan 420111, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Kazakova","sequence":"additional","affiliation":[{"name":"Biochemical Neuropharmacology Laboratory, Kazan Federal University, Kremlevskaya Str., 18, Kazan 420111, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinara","family":"Shambazova","sequence":"additional","affiliation":[{"name":"Biochemical Neuropharmacology Laboratory, Kazan Federal University, Kremlevskaya Str., 18, Kazan 420111, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Bogdanov","sequence":"additional","affiliation":[{"name":"Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9960-7499","authenticated-orcid":true,"given":"Dmitry","family":"Tatarinov","sequence":"additional","affiliation":[{"name":"Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Daud\u00e9","sequence":"additional","affiliation":[{"name":"Gene&GreenTK, 19\u221221 Boulevard Jean Moulin, Marseille 13005, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Jacquet","sequence":"additional","affiliation":[{"name":"Gene&GreenTK, 19\u221221 Boulevard Jean Moulin, Marseille 13005, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Chabri\u00e8re","sequence":"additional","affiliation":[{"name":"Gene&GreenTK, 19\u221221 Boulevard Jean Moulin, Marseille 13005, France"},{"name":"Aix Marseille University, IRD, APHM, MEPHI, IHU-M\u00e9diterran\u00e9e Infection, 19-21 Boulevard Jean Moulin, Marseille 13005, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Masson","sequence":"additional","affiliation":[{"name":"Biochemical Neuropharmacology Laboratory, Kazan Federal University, Kremlevskaya Str., 18, Kazan 420111, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,4,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-010818-021842"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2020.108298"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X11311030006"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14026"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201503320"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1039\/c9nr09015k"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201870049"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2012.264"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.1c01201"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2015.05.005"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3008736"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.03.035"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b04163"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2020.152578"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.10.010"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2018.07.049"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.1c00361"},{"key":"ref18\/cit18","unstructured":"Jacquet, P. Am\u00e9lioration d\u2019une Enzyme Hyperthermostable Pour La D\u00e9gradation Des Organophosphor\u00e9s. Ph.D. Thesis, Aix-Marseille University (France), 2017."},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(91)90444-G"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1006\/taap.1993.1154"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/0009-2797(93)90055-4"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfg185"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aau7091"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2021.109577"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1126\/science.284.5417.1143"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/la990951u"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/la025897n"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1039\/C9MH01669D"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2021.101096"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1126\/science.1074972"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/bit.1045"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.9b01754"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22137134"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/C5BM00360A"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.101008"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1678"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.36376"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2021.110387"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03001-9"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20184583"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.05.006"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.10.026"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-018-2069-x"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1039\/D1NR02188E"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(98)00035-5"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2019.04.013"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/srep37780"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-16841-0"},{"key":"ref49\/cit49","unstructured":"Davis, F.; Van\nEs, T.; Palczuk, N. Non-Immunogenic Polypeptides. U.S. Patent 4,179,337 A, 1979."},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3390\/polym4010561"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/ma0108057"},{"key":"ref52\/cit52","first-page":"37","volume-title":"Current Protocols in Mouse Biology","volume":"2","author":"Brooks S. P.","year":"2012"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22147742"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/la900779t"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/ma051176u"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/bm070085x"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.04.060"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/mp7001297"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/la0357054"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.02.024"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.07.026"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b09906"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.202100062"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-018-2465-5"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2013.11.001"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1039\/D0CC00925C"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1007\/s11051-013-2101-8"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1115\/1.4037124"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10040784"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.0c01196"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c03210","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c03210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T18:33:49Z","timestamp":1682447629000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.2c03210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,19]]},"references-count":70,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2022,5,4]]}},"alternative-id":["10.1021\/acsami.2c03210"],"URL":"https:\/\/doi.org\/10.1021\/acsami.2c03210","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,19]]}}}