{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:08:55Z","timestamp":1791378535138,"version":"4.3.2"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"25","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000010","name":"Ford Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["75N93019C00052"],"award-info":[{"award-number":["75N93019C00052"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI147497"],"award-info":[{"award-number":["R01AI147497"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000082","name":"Division of Graduate Education","doi-asserted-by":"publisher","award":["DGE-1650116"],"award-info":[{"award-number":["DGE-1650116"]}],"id":[{"id":"10.13039\/100000082","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2022,6,29]]},"DOI":"10.1021\/acsami.2c04671","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T16:30:36Z","timestamp":1655310636000},"page":"28548-28558","source":"Crossref","is-referenced-by-count":33,"title":["Metal\u2013Organic Coordination Polymer for Delivery of a Subunit Broadly Acting Influenza Vaccine"],"prefix":"10.1021","volume":"14","author":[{"given":"Meital","family":"Eckshtain-Levi","sequence":"first","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5631-2623","authenticated-orcid":true,"given":"Cole J.","family":"Batty","sequence":"additional","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liubov M.","family":"Lifshits","sequence":"additional","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"McCammitt","sequence":"additional","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn M.","family":"Moore","sequence":"additional","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva A.","family":"Amouzougan","sequence":"additional","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebeca T.","family":"Stiepel","sequence":"additional","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"Duggan","sequence":"additional","affiliation":[{"name":"North Carolina School of Science and Mathematics, Durham, North Carolina 27705, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ted M.","family":"Ross","sequence":"additional","affiliation":[{"name":"Center for Vaccines and Immunology, University of Georgia, Athens, Georgia 30602, United States"},{"name":"Department of Infectious Diseases, University of Georgia, Athens, Georgia 30602, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8572-888X","authenticated-orcid":true,"given":"Eric M.","family":"Bachelder","sequence":"additional","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1820-8382","authenticated-orcid":true,"given":"Kristy M.","family":"Ainslie","sequence":"additional","affiliation":[{"name":"Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"},{"name":"Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"},{"name":"Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, North Carolina 27514, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,6,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b20504"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.212643999"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00188"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0901592106"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.11.030"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/mp800068x"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201307074"},{"key":"ref8\/cit8","volume-title":"Biomolecule Encapsulation in Biocompatible Metal-Organic Frameworks","author":"Pullin T. M.","year":"2019"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201600642"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/cg801381p"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c01089"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b05974"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2021.213977"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3201\/eid1201.051254"},{"key":"ref15\/cit15","unstructured":"CDC, 2009\nH1n1 Pandemic (H1n1pdm09\nVirus). Centers for Disease Control and Prevention, N. C. f. I. a.\nR. D. N., Ed. cdc.gov, 2019."},{"key":"ref16\/cit16","volume-title":"Immunobiology.","author":"Janeway C.","year":"2001","edition":"5"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03152-15"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRev.56.978"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2016.04.010"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889813013113"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1039\/C9CE00757A"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c00706"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.119983"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.02.035"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201504998"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c03092"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.11.4942"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.09.020"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/anbr.202000041"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.03.011"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00152-06"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b01680"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201600650"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/b807085g"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03152-15"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204284"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01349-18"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1900379"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8240"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.08.031"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.144627"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.202000100"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-14-0019-T"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.11.063"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.03018"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2020.03.026"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.10.054"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012279"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.26.15553"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c10276"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.8b00579"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1759(98)00170-7"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c04671","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c04671","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T03:29:47Z","timestamp":1682479787000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.2c04671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,15]]},"references-count":52,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2022,6,29]]}},"alternative-id":["10.1021\/acsami.2c04671"],"URL":"https:\/\/doi.org\/10.1021\/acsami.2c04671","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,15]]}}}